RS54072B1 - Kompozicije za primenu u lečenju virusnih infekcija - Google Patents
Kompozicije za primenu u lečenju virusnih infekcijaInfo
- Publication number
- RS54072B1 RS54072B1 RS20150369A RSP20150369A RS54072B1 RS 54072 B1 RS54072 B1 RS 54072B1 RS 20150369 A RS20150369 A RS 20150369A RS P20150369 A RSP20150369 A RS P20150369A RS 54072 B1 RS54072 B1 RS 54072B1
- Authority
- RS
- Serbia
- Prior art keywords
- virus
- compound
- influenza
- viral
- group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/06—Heterocyclic radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39352210P | 2010-10-15 | 2010-10-15 | |
| US201161492054P | 2011-06-01 | 2011-06-01 | |
| PCT/US2011/056421 WO2012051570A1 (en) | 2010-10-15 | 2011-10-14 | Methods and compositions for inhibition of polymerase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS54072B1 true RS54072B1 (sr) | 2015-10-30 |
Family
ID=45938737
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20150369A RS54072B1 (sr) | 2010-10-15 | 2011-10-14 | Kompozicije za primenu u lečenju virusnih infekcija |
| RS20180135A RS56870B1 (sr) | 2010-10-15 | 2011-10-14 | Pirolopirimidinski derivati za primenu u lečenju virusnih infekcija |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20180135A RS56870B1 (sr) | 2010-10-15 | 2011-10-14 | Pirolopirimidinski derivati za primenu u lečenju virusnih infekcija |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US20130331404A1 (https=) |
| EP (3) | EP3345605B1 (https=) |
| JP (2) | JP5902698B2 (https=) |
| KR (1) | KR101850925B1 (https=) |
| CN (1) | CN103429245B (https=) |
| AU (2) | AU2011315902B2 (https=) |
| BR (1) | BR112013009029B1 (https=) |
| CA (1) | CA2813783C (https=) |
| CY (1) | CY1119880T1 (https=) |
| DK (2) | DK2627334T3 (https=) |
| ES (2) | ES2657687T3 (https=) |
| HR (2) | HRP20150487T1 (https=) |
| HU (1) | HUE036387T2 (https=) |
| IL (1) | IL225672B (https=) |
| LT (1) | LT2898885T (https=) |
| MX (1) | MX348759B (https=) |
| PL (2) | PL2898885T3 (https=) |
| PT (2) | PT2627334E (https=) |
| RS (2) | RS54072B1 (https=) |
| RU (3) | RU2718690C2 (https=) |
| SI (2) | SI2627334T1 (https=) |
| SM (2) | SMT201800064T1 (https=) |
| WO (1) | WO2012051570A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2398684T3 (es) | 2008-04-23 | 2013-03-21 | Gilead Sciences, Inc. | Análogos de carbanucleósido para el tratamiento antiviral |
| TWI483950B (zh) | 2009-09-21 | 2015-05-11 | Gilead Sciences Inc | 用於製備１’－取代碳核苷類似物之方法及中間物 |
| KR101995598B1 (ko) | 2010-07-19 | 2019-07-02 | 길리애드 사이언시즈, 인코포레이티드 | 부분입체 이성질성으로 순수한 포스포라미데이트 전구약물의 제조 방법 |
| BR122020020745B8 (pt) | 2010-07-22 | 2023-10-31 | Gilead Sciences Inc | Composto antiviral para o tratamento de infecções por paramyxoviridae e composição farmacêutica que o compreende |
| PL2898885T3 (pl) * | 2010-10-15 | 2018-04-30 | Biocryst Pharmaceuticals, Inc. | Pochodne pirolopirymidynowe do zastosowania w leczeniu zakażeń wirusowych |
| AR090699A1 (es) * | 2012-04-18 | 2014-12-03 | Biocryst Pharm Inc | Compuestos inhibidores de la actividad de la arn polimerasa viral |
| WO2014078778A2 (en) * | 2012-11-16 | 2014-05-22 | Biocryst Pharmaceuticals, Inc. | Antiviral azasugar-containing nucleosides |
| US9499554B2 (en) | 2013-05-14 | 2016-11-22 | Biocryst Pharmaceuticals, Inc. | Anti-influenza compositions and methods |
| TWI678369B (zh) * | 2014-07-28 | 2019-12-01 | 美商基利科學股份有限公司 | 用於治療呼吸道合胞病毒感染之噻吩並［３,２-ｄ］嘧啶、呋喃並［３,２-ｄ］嘧啶及吡咯並［３,２-ｄ］嘧啶化合物類 |
| TWI767201B (zh) | 2014-10-29 | 2022-06-11 | 美商基利科學股份有限公司 | 絲狀病毒科病毒感染之治療 |
| CN104513249B (zh) * | 2014-12-26 | 2016-08-31 | 苏州明锐医药科技有限公司 | 抗埃博拉病毒药物bcx4430的制备方法 |
| SI3349758T1 (sl) | 2015-09-16 | 2022-08-31 | Gilead Sciences, Inc. | Postopki za zdravljenje okužb z virusom arenaviridae |
| WO2017155886A1 (en) | 2016-03-06 | 2017-09-14 | Biocryst Pharmaceuticals, Inc. | Methods and compositions for treatment of zika virus infection |
| DE102016002873A1 (de) | 2016-03-09 | 2016-05-25 | Heinz Kiefer | Zellnachweisverfahren und Screeningverfahren von Stoffbibliotheken zur Identifizierung von Einzelstoffen, die im Falle einer bioterroristischen Bedrohung gegen Mischungen synthetischer Viren wirksam sind |
| US10682368B2 (en) | 2017-03-14 | 2020-06-16 | Gilead Sciences, Inc. | Methods of treating feline coronavirus infections |
| AU2018262501B2 (en) | 2017-05-01 | 2020-12-10 | Gilead Sciences, Inc. | Crystalline forms of (S) 2 ethylbutyl 2 (((S) (((2R,3S,4R,5R) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate |
| WO2019014247A1 (en) | 2017-07-11 | 2019-01-17 | Gilead Sciences, Inc. | COMPOSITIONS COMPRISING POLYMERASE RNA INHIBITOR AND CYCLODEXTRIN FOR THE TREATMENT OF VIRAL INFECTIONS |
| WO2021007283A1 (en) * | 2019-07-09 | 2021-01-14 | Regents Of The University Of Minnesota | Potentiation of antiviral nucleobases as rna virus therapy |
| US11660307B2 (en) | 2020-01-27 | 2023-05-30 | Gilead Sciences, Inc. | Methods for treating SARS CoV-2 infections |
| JP7554841B2 (ja) | 2020-03-12 | 2024-09-20 | ギリアード サイエンシーズ， インコーポレイテッド | １’－シアノヌクレオシドを調製する方法 |
| WO2021207049A1 (en) | 2020-04-06 | 2021-10-14 | Gilead Sciences, Inc. | Inhalation formulations of 1'-cyano substituted carbanucleoside analogs |
| WO2021207386A1 (en) * | 2020-04-07 | 2021-10-14 | Biocryst Pharmaceuticals, Inc. | Methods, compositions, and dosing regimens for treatment of sars-cov-2 infections |
| CA3179226A1 (en) | 2020-05-29 | 2021-12-02 | Tomas Cihlar | Remdesivir treatment methods |
| AU2021296841B2 (en) | 2020-06-24 | 2025-01-23 | Gilead Sciences, Inc. | 1'-cyano nucleoside analogs and uses thereof |
| SI4204421T1 (sl) | 2020-08-27 | 2024-07-31 | Gilead Sciences, Inc., | Spojine in postopki za zdravljenje virusnih okužb |
| KR102871928B1 (ko) * | 2021-06-25 | 2025-10-20 | 전남대학교 산학협력단 | 지방분해효소 억제제를 포함하는 rna 바이러스 감염증 예방 또는 치료용 약제학적 조성물 |
| EP4360629A4 (en) * | 2021-06-25 | 2024-11-06 | Industry Foundation of Chonnam National University | PHARMACEUTICAL COMPOSITION COMPRISING A LIPASE INHIBITOR FOR THE TREATMENT OF RNA VIRAL INFECTIONS |
| JP2024531898A (ja) * | 2021-08-17 | 2024-09-03 | サウスウエスト リサーチ インスティテュート | コロナウイルスに対する阻害剤 |
| CN115925640B (zh) * | 2021-08-23 | 2025-03-28 | 中国人民解放军军事科学院军事医学研究院 | ((3-氨甲酰-5-氟吡嗪-2-基)氧基)甲基异丁酸酯及其制备方法和应用 |
| US12552827B2 (en) | 2022-01-21 | 2026-02-17 | Biocryst Pharmaceuticals, Inc. | Synthesis of an antiviral azasugar triphosphate |
| IL315102A (en) | 2022-03-02 | 2024-10-01 | Gilead Sciences Inc | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS |
| US12357577B1 (en) | 2024-02-02 | 2025-07-15 | Gilead Sciences, Inc. | Pharmaceutical formulations and uses thereof |
| CN118359621B (zh) * | 2024-04-16 | 2025-05-16 | 上海陶术生物科技股份有限公司 | 加利司伟及加利司伟中间体的制备方法和相应的加利司伟中间体 |
| CN118359622B (zh) * | 2024-04-16 | 2025-08-26 | 上海陶术生物科技股份有限公司 | 加利司伟中间体的制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9520364D0 (en) * | 1995-10-05 | 1995-12-06 | Chiroscience Ltd | Compouundds |
| US5985848A (en) * | 1997-10-14 | 1999-11-16 | Albert Einstein College Of Medicine Of Yeshiva University | Inhibitors of nucleoside metabolism |
| US6228741B1 (en) | 1998-01-13 | 2001-05-08 | Texas Instruments Incorporated | Method for trench isolation of semiconductor devices |
| US7388002B2 (en) | 2001-11-14 | 2008-06-17 | Biocryst Pharmaceuticals, Inc. | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases |
| US7098334B2 (en) * | 2002-03-25 | 2006-08-29 | Industrial Research Limited | 4-amino-5H-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases |
| US20050250728A1 (en) * | 2002-05-23 | 2005-11-10 | Shanta Bantia | Enhancing the efficacy of reverse transcriptase and dna polymerase inhibitors (nucleoside analogs) using pnp inhibitors and/or 2'-deoxyguanosine and/or prodrug thereof |
| US7560434B2 (en) * | 2004-06-22 | 2009-07-14 | Biocryst Pharmaceuticals, Inc. | AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases |
| EP1863500A2 (en) * | 2005-03-29 | 2007-12-12 | Biocryst Pharmaceuticals, Inc. | Hepatitis c therapies |
| US20090227637A1 (en) * | 2005-12-15 | 2009-09-10 | Olaf Weber | Diaryl ureas for treating virus infections |
| NZ575365A (en) | 2006-09-07 | 2012-02-24 | Ind Res Ltd | Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases |
| CA2663618A1 (en) | 2006-09-11 | 2008-06-05 | Southern Research Institute | Azole nucleosides and use as inhibitors of rna and dna viral polymerases |
| TW200942243A (en) | 2008-03-05 | 2009-10-16 | Biocryst Pharm Inc | Antiviral therapeutic agents |
| PL2898885T3 (pl) * | 2010-10-15 | 2018-04-30 | Biocryst Pharmaceuticals, Inc. | Pochodne pirolopirymidynowe do zastosowania w leczeniu zakażeń wirusowych |
| PH12013500954A1 (en) * | 2010-11-11 | 2017-05-19 | Redx Pharma Plc | Drug derivatives |
| AR090699A1 (es) * | 2012-04-18 | 2014-12-03 | Biocryst Pharm Inc | Compuestos inhibidores de la actividad de la arn polimerasa viral |
-
2011
- 2011-10-14 PL PL14198125T patent/PL2898885T3/pl unknown
- 2011-10-14 SI SI201130489T patent/SI2627334T1/sl unknown
- 2011-10-14 RS RS20150369A patent/RS54072B1/sr unknown
- 2011-10-14 US US13/879,110 patent/US20130331404A1/en not_active Abandoned
- 2011-10-14 LT LTEP14198125.8T patent/LT2898885T/lt unknown
- 2011-10-14 JP JP2013534046A patent/JP5902698B2/ja active Active
- 2011-10-14 CA CA2813783A patent/CA2813783C/en active Active
- 2011-10-14 PT PT118335157T patent/PT2627334E/pt unknown
- 2011-10-14 SI SI201131383T patent/SI2898885T1/en unknown
- 2011-10-14 EP EP17196354.9A patent/EP3345605B1/en active Active
- 2011-10-14 BR BR112013009029-4A patent/BR112013009029B1/pt active IP Right Grant
- 2011-10-14 DK DK11833515.7T patent/DK2627334T3/en active
- 2011-10-14 EP EP14198125.8A patent/EP2898885B1/en active Active
- 2011-10-14 ES ES14198125.8T patent/ES2657687T3/es active Active
- 2011-10-14 KR KR1020137012318A patent/KR101850925B1/ko active Active
- 2011-10-14 CN CN201180059786.9A patent/CN103429245B/zh active Active
- 2011-10-14 HU HUE14198125A patent/HUE036387T2/hu unknown
- 2011-10-14 MX MX2013003938A patent/MX348759B/es active IP Right Grant
- 2011-10-14 RS RS20180135A patent/RS56870B1/sr unknown
- 2011-10-14 SM SM20180064T patent/SMT201800064T1/it unknown
- 2011-10-14 DK DK14198125.8T patent/DK2898885T3/en active
- 2011-10-14 ES ES11833515.7T patent/ES2536831T3/es active Active
- 2011-10-14 AU AU2011315902A patent/AU2011315902B2/en active Active
- 2011-10-14 HR HRP20150487TT patent/HRP20150487T1/hr unknown
- 2011-10-14 PT PT141981258T patent/PT2898885T/pt unknown
- 2011-10-14 EP EP11833515.7A patent/EP2627334B1/en active Active
- 2011-10-14 WO PCT/US2011/056421 patent/WO2012051570A1/en not_active Ceased
- 2011-10-14 RU RU2016134401A patent/RU2718690C2/ru active
- 2011-10-14 PL PL11833515T patent/PL2627334T3/pl unknown
- 2011-10-14 RU RU2013121794/15A patent/RU2599013C2/ru active
-
2013
- 2013-04-10 IL IL225672A patent/IL225672B/en active IP Right Grant
-
2014
- 2014-11-03 US US14/531,471 patent/US9492452B2/en active Active
-
2015
- 2015-06-25 SM SM201500148T patent/SMT201500148B/xx unknown
-
2016
- 2016-03-10 JP JP2016046875A patent/JP2016135790A/ja not_active Withdrawn
- 2016-10-28 US US15/337,320 patent/US10022375B2/en active Active
-
2017
- 2017-01-24 AU AU2017200471A patent/AU2017200471B2/en active Active
-
2018
- 2018-02-02 CY CY20181100131T patent/CY1119880T1/el unknown
- 2018-02-06 HR HRP20180220TT patent/HRP20180220T1/hr unknown
- 2018-06-20 US US16/013,059 patent/US10420769B2/en active Active
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2019
- 2019-08-16 US US16/543,079 patent/US11173159B2/en active Active
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2020
- 2020-03-17 RU RU2020111042A patent/RU2020111042A/ru unknown
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2021
- 2021-10-21 US US17/506,836 patent/US12508266B2/en active Active
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