RS51068B - Derivati-5-piridinil-1-azabiciklo[3.2.1]oktana, njihovo dobijanje i njihova terapeutska primena - Google Patents
Derivati-5-piridinil-1-azabiciklo[3.2.1]oktana, njihovo dobijanje i njihova terapeutska primenaInfo
- Publication number
- RS51068B RS51068B RSP-2009/0576A RSP20090576A RS51068B RS 51068 B RS51068 B RS 51068B RS P20090576 A RSP20090576 A RS P20090576A RS 51068 B RS51068 B RS 51068B
- Authority
- RS
- Serbia
- Prior art keywords
- therapeutics
- same
- azabicyclo
- pyridinyl
- octane
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Jedinjenja koja odgovaraju formuli (I)u kojoj:R predstavlja grupu odabranu od pirazolila, imidazolila, triazolila, oksazolila, oksadiazolila, tiazolila, izo-tiazolila, tiadiazolila, tetrazolila. Ova grupa može eventualno biti supstituisana jednom ili više grupa odabranih od atoma halogena, grupa (C1-C6)alkil, (C1-C6)alkoksi, trifluorometoksi, trifluorometil, nitro, cijano, hidroksi, amino, (C1-C6)alkilamino ili di(C1-C6)alkilamino; veza između ugljenika na položajima 3 i 4 prstena azabiciklo oktana je jednoguba ili dvogubau vidu baze ili adicione soli kiseline, kao i u stanju hidrata ili solvata.Prijava sadrži još 20 zavisnih patentnih zahteva.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0508528A FR2889701B1 (fr) | 2005-08-12 | 2005-08-12 | Derives de 5-pyridinyl-1-azabicyclo[3.2.1]octane, leur preparation en therapeutique. |
PCT/FR2006/001912 WO2007020344A1 (fr) | 2005-08-12 | 2006-08-07 | DÉRIVÉS DE δ-PYRIDINYL-i-AZABICYCLO[3.2.1]OCTANE, A LEUR PRÉPARATION ET LEUR APPLICATION EN THÉRAPEUTIQUE |
Publications (1)
Publication Number | Publication Date |
---|---|
RS51068B true RS51068B (sr) | 2010-10-31 |
Family
ID=36273387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RSP-2009/0576A RS51068B (sr) | 2005-08-12 | 2006-08-07 | Derivati-5-piridinil-1-azabiciklo[3.2.1]oktana, njihovo dobijanje i njihova terapeutska primena |
Country Status (41)
Country | Link |
---|---|
US (2) | US7863290B2 (sr) |
EP (1) | EP1915375B1 (sr) |
JP (1) | JP5164841B2 (sr) |
KR (1) | KR101299339B1 (sr) |
CN (1) | CN101238125B (sr) |
AT (1) | ATE444964T1 (sr) |
AU (1) | AU2006281341B2 (sr) |
BR (1) | BRPI0614623A2 (sr) |
CA (1) | CA2617828C (sr) |
CR (1) | CR9625A (sr) |
CY (1) | CY1109717T1 (sr) |
DE (1) | DE602006009668D1 (sr) |
DK (1) | DK1915375T3 (sr) |
DO (1) | DOP2006000180A (sr) |
EA (1) | EA014023B1 (sr) |
EC (1) | ECSP088170A (sr) |
ES (1) | ES2332472T3 (sr) |
FR (1) | FR2889701B1 (sr) |
GT (1) | GT200600368A (sr) |
HK (1) | HK1120788A1 (sr) |
HN (1) | HN2008000090A (sr) |
HR (1) | HRP20090677T1 (sr) |
IL (1) | IL188796A (sr) |
JO (1) | JO2583B1 (sr) |
MA (1) | MA30200B1 (sr) |
ME (1) | ME01750B (sr) |
MX (1) | MX2008001968A (sr) |
MY (1) | MY147846A (sr) |
NO (1) | NO20081151L (sr) |
NZ (1) | NZ565149A (sr) |
PE (1) | PE20070339A1 (sr) |
PL (1) | PL1915375T3 (sr) |
PT (1) | PT1915375E (sr) |
RS (1) | RS51068B (sr) |
SI (1) | SI1915375T1 (sr) |
TN (1) | TNSN07472A1 (sr) |
TW (1) | TWI324158B (sr) |
UA (1) | UA92917C2 (sr) |
UY (1) | UY29744A1 (sr) |
WO (1) | WO2007020344A1 (sr) |
ZA (1) | ZA200800958B (sr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2912404B1 (fr) * | 2007-02-09 | 2009-04-10 | Sanofi Aventis Sa | Derives d'azabicycloalkane,leur preparation et leur application en therapeutique. |
GB0817424D0 (en) | 2008-09-24 | 2008-10-29 | Medivir Ab | Protease inhibitors |
JP2017114765A (ja) * | 2014-04-25 | 2017-06-29 | 大正製薬株式会社 | トリアゾリルで置換されたヘテロアリール化合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5817679A (en) * | 1993-04-01 | 1998-10-06 | University Of Virginia | 7-Azabicyclo 2.2.1!-heptane and -heptene derivatives as cholinergic receptor ligands |
EP0664293A1 (en) * | 1993-12-24 | 1995-07-26 | Duphar International Research B.V | 2-Phenyl-7-azabicycloheptanes and 6-phenyl-8-azabicyclo |
KR100589872B1 (ko) * | 1997-05-30 | 2006-06-15 | 뉴로서치 에이/에스 | 8-아자비사이클로(3,2,1)옥트-2-엔 유도체 및 이의 제조방법 |
FR2834511B1 (fr) | 2002-01-07 | 2004-02-13 | Sanofi Synthelabo | Derives de 5-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, leur preparation et leur application en therapeutique |
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2005
- 2005-08-12 FR FR0508528A patent/FR2889701B1/fr active Active
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2006
- 2006-07-08 UA UAA200802988A patent/UA92917C2/uk unknown
- 2006-07-26 JO JO2006252A patent/JO2583B1/en active
- 2006-08-02 DO DO2006000180A patent/DOP2006000180A/es unknown
- 2006-08-07 DE DE602006009668T patent/DE602006009668D1/de active Active
- 2006-08-07 EA EA200800575A patent/EA014023B1/ru not_active IP Right Cessation
- 2006-08-07 CA CA2617828A patent/CA2617828C/fr not_active Expired - Fee Related
- 2006-08-07 PT PT06794298T patent/PT1915375E/pt unknown
- 2006-08-07 ES ES06794298T patent/ES2332472T3/es active Active
- 2006-08-07 SI SI200630515T patent/SI1915375T1/sl unknown
- 2006-08-07 WO PCT/FR2006/001912 patent/WO2007020344A1/fr active Application Filing
- 2006-08-07 DK DK06794298.7T patent/DK1915375T3/da active
- 2006-08-07 CN CN2006800291833A patent/CN101238125B/zh not_active Expired - Fee Related
- 2006-08-07 AT AT06794298T patent/ATE444964T1/de active
- 2006-08-07 PL PL06794298T patent/PL1915375T3/pl unknown
- 2006-08-07 NZ NZ565149A patent/NZ565149A/en not_active IP Right Cessation
- 2006-08-07 RS RSP-2009/0576A patent/RS51068B/sr unknown
- 2006-08-07 MX MX2008001968A patent/MX2008001968A/es active IP Right Grant
- 2006-08-07 AU AU2006281341A patent/AU2006281341B2/en not_active Ceased
- 2006-08-07 BR BRPI0614623-6A patent/BRPI0614623A2/pt not_active IP Right Cessation
- 2006-08-07 ME MEP-2009-576A patent/ME01750B/me unknown
- 2006-08-07 ZA ZA200800958A patent/ZA200800958B/xx unknown
- 2006-08-07 KR KR1020087003271A patent/KR101299339B1/ko not_active IP Right Cessation
- 2006-08-07 EP EP06794298A patent/EP1915375B1/fr active Active
- 2006-08-07 JP JP2008525599A patent/JP5164841B2/ja not_active Expired - Fee Related
- 2006-08-10 GT GT200600368A patent/GT200600368A/es unknown
- 2006-08-10 PE PE2006000974A patent/PE20070339A1/es not_active Application Discontinuation
- 2006-08-10 MY MYPI20063888A patent/MY147846A/en unknown
- 2006-08-11 TW TW095129651A patent/TWI324158B/zh not_active IP Right Cessation
- 2006-08-11 UY UY29744A patent/UY29744A1/es not_active Application Discontinuation
-
2007
- 2007-12-14 TN TNP2007000472A patent/TNSN07472A1/en unknown
- 2007-12-20 CR CR9625A patent/CR9625A/es unknown
-
2008
- 2008-01-15 IL IL188796A patent/IL188796A/en not_active IP Right Cessation
- 2008-01-22 HN HN2008000090A patent/HN2008000090A/es unknown
- 2008-02-11 EC EC2008008170A patent/ECSP088170A/es unknown
- 2008-02-11 US US12/028,999 patent/US7863290B2/en not_active Expired - Fee Related
- 2008-03-04 NO NO20081151A patent/NO20081151L/no not_active Application Discontinuation
- 2008-03-07 MA MA30724A patent/MA30200B1/fr unknown
- 2008-11-11 HK HK08112365.4A patent/HK1120788A1/xx not_active IP Right Cessation
-
2009
- 2009-12-17 HR HR20090677T patent/HRP20090677T1/hr unknown
-
2010
- 2010-01-05 CY CY20101100013T patent/CY1109717T1/el unknown
- 2010-11-29 US US12/955,389 patent/US8541440B2/en not_active Expired - Fee Related
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