RS50891B - Postupak za pripremanje rastvora albumina - Google Patents

Postupak za pripremanje rastvora albumina

Info

Publication number
RS50891B
RS50891B YUP-2005/0624A YUP20050624A RS50891B RS 50891 B RS50891 B RS 50891B YU P20050624 A YUP20050624 A YU P20050624A RS 50891 B RS50891 B RS 50891B
Authority
RS
Serbia
Prior art keywords
albumin solution
stabilizer
optionally
groups
hydrophobic
Prior art date
Application number
YUP-2005/0624A
Other languages
English (en)
Inventor
Werner Gehringer
Katharina Pock
Jürgen Römisch
Tor-Einar Svae
Christoph Kannicht
Original Assignee
Octapharma Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octapharma Ag. filed Critical Octapharma Ag.
Publication of RS20050624A publication Critical patent/RS20050624A/sr
Publication of RS50891B publication Critical patent/RS50891B/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Abstract

Postupak pripremanja albumina, naznačen time, što se sastoji od kombinacije sledećih koraka:(a) podvrgavanje prvog vodenog rastvora albumina tretmanu za virus-dezaktiviranje putem SD postupka njegovim kontaktiranjem sa SD reagensima na temperaturi ispod 45°C;(b) uklanjanje, bar suštinski, SD reagensa putem ekstrakcije ulja praćene hromatografijom hidrofobične interakcije, pri čemu je hidrofobična matrica, posebno matrica za koju hidrofobične grupe mogu opciono biti vezane, upotrebljene za navedenu hromatografiju, pod uslovom da su navedene grupe alifatične grupe sa više od 24 atoma ugljenika, da se dobije drugi rastvor albumina za koji se(c) dodaju opciono jedan ili više stabilizatora odabranih iz grupe šećera, amino kiselina i šećernih alkohola, pod uslovom da se ne upošljavaju kao navedeni stabilizator indol stabilizator i C6-C10 masna kiselina, nakon čega(d) se navedeni drugi rastvor albumina kome je stabilizator opciono dodat podvrgne konačnom pakovanju i sterilnom filtriranju i opciono puni u konačne kontejnere.Prijava sadrži još 17 zavisnih patentnih zahteva.
YUP-2005/0624A 2003-02-13 2004-02-13 Postupak za pripremanje rastvora albumina RS50891B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT2182003 2003-02-13
PCT/EP2004/001397 WO2004071524A1 (de) 2003-02-13 2004-02-13 Albuminlösung und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
RS20050624A RS20050624A (en) 2007-06-04
RS50891B true RS50891B (sr) 2010-08-31

Family

ID=32854882

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2005/0624A RS50891B (sr) 2003-02-13 2004-02-13 Postupak za pripremanje rastvora albumina

Country Status (22)

Country Link
EP (1) EP1592439B1 (sr)
JP (1) JP2006517938A (sr)
KR (1) KR20050103292A (sr)
CN (1) CN100384471C (sr)
AT (1) ATE362376T1 (sr)
AU (1) AU2004212324B2 (sr)
BR (1) BRPI0407458A (sr)
CA (1) CA2514163A1 (sr)
CY (1) CY1106793T1 (sr)
DE (1) DE502004003834D1 (sr)
DK (1) DK1592439T3 (sr)
ES (1) ES2285427T3 (sr)
IL (1) IL169828A0 (sr)
MX (1) MXPA05008276A (sr)
NO (1) NO20053677L (sr)
PL (1) PL376644A1 (sr)
PT (1) PT1592439E (sr)
RS (1) RS50891B (sr)
RU (1) RU2305556C2 (sr)
UA (1) UA80469C2 (sr)
WO (1) WO2004071524A1 (sr)
ZA (1) ZA200506452B (sr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005023155A1 (de) * 2005-05-13 2006-11-16 Albutec Gmbh Albuminlösung
US20100168000A1 (en) 2005-12-22 2010-07-01 Peter Kiessling Octanoate-Reduced Human Albumin
ES2332846B1 (es) 2007-10-26 2010-07-08 Grifols, S.A. Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos.
ES2294976B1 (es) 2007-11-12 2008-12-16 Grifols, S.A. "procedimiento de obtencion de albumina humana de alta eficacia para su uso en terapia de detoxificacion".
EP2382993A1 (en) 2010-04-19 2011-11-02 KTB Tumorforschungsgesellschaft mbH Combination of drugs with protein-binding prodrugs
CN111195351A (zh) * 2020-01-20 2020-05-26 华兰生物工程重庆有限公司 5%低浓度人血白蛋白的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0669961B2 (ja) * 1984-09-25 1994-09-07 株式会社ミドリ十字 免疫グロブリンの加熱処理方法
US5094960A (en) * 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5250662A (en) * 1989-10-05 1993-10-05 Alpha Therapeutic Corporation Albumin purification
DE19729778A1 (de) * 1997-07-11 1999-01-21 Blutspendedienst Der Drk Lande Verfahren zur Herstellung von virusinaktivierten biologischen Flüssigkeiten
US5919907A (en) * 1997-12-22 1999-07-06 Shanbrom Technologies Llc Preparation and utilization of a novel sterile albumin
IL136552A (en) * 2000-06-05 2005-05-17 Omrix Biopharmaceuticals Ltd Method for the inactivation of viruses by a solvent - detergent combination and by nanofiltration

Also Published As

Publication number Publication date
EP1592439A1 (de) 2005-11-09
JP2006517938A (ja) 2006-08-03
CN1798573A (zh) 2006-07-05
BRPI0407458A (pt) 2006-01-31
AU2004212324B2 (en) 2009-05-07
RU2005128507A (ru) 2006-01-20
WO2004071524A1 (de) 2004-08-26
CY1106793T1 (el) 2012-05-23
KR20050103292A (ko) 2005-10-28
DE502004003834D1 (de) 2007-06-28
RS20050624A (en) 2007-06-04
NO20053677L (no) 2005-10-31
ATE362376T1 (de) 2007-06-15
RU2305556C2 (ru) 2007-09-10
CN100384471C (zh) 2008-04-30
AU2004212324A1 (en) 2004-08-26
PT1592439E (pt) 2007-06-22
DK1592439T3 (da) 2007-09-10
ES2285427T3 (es) 2007-11-16
PL376644A1 (pl) 2006-01-09
ZA200506452B (en) 2007-01-31
CA2514163A1 (en) 2004-08-26
MXPA05008276A (es) 2006-03-21
NO20053677D0 (no) 2005-07-29
IL169828A0 (en) 2011-08-01
UA80469C2 (en) 2007-09-25
EP1592439B1 (de) 2007-05-16

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