RS50057B - Komopzicije oksikodona sa kontrolisanim oslobađanjem - Google Patents

Komopzicije oksikodona sa kontrolisanim oslobađanjem

Info

Publication number
RS50057B
RS50057B YUP-2005/0411A YU41105A RS50057B RS 50057 B RS50057 B RS 50057B YU 41105 A YU41105 A YU 41105A RS 50057 B RS50057 B RS 50057B
Authority
RS
Serbia
Prior art keywords
controlled release
oxycodone
oxycodon
compositions
water
Prior art date
Application number
YUP-2005/0411A
Other languages
English (en)
Inventor
Benjamin OSHLACK
John Joseph Minogue
Robert Francis Kaiko
Mark Chasin
Original Assignee
Euro-Celtique S.A.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro-Celtique S.A., filed Critical Euro-Celtique S.A.,
Publication of YU20050411A publication Critical patent/YU20050411A/sh
Publication of RS50057B publication Critical patent/RS50057B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Postupak proizvodnje formulacije sa kontrolisanim oslobađanj em koja .sadrži. so oksikodona inkorporisanu u matrici za kontrolisano oslobađanje, naznačen time, što se (a) formiraj u granule koj e sadrže bar jednu vodorastvornu hidroksialkil celulozu i so oksikodona, vlažnom granulacijom sa vodom; (b) mešanju granula koje sadrže hidroksialkil celulozu sa bar jednim C12-C36alifatskim alkoholom; gde pomenuta formulacija sadržr 10 do 160 mg oksikodon hidrohlorida; pomenuta formulacij a sa kontrolisanim oslobađanjem se koristi da prihvatljivo kontroliše bol kod suštinski svih humanih pacijenata, pri ravnotežnom stanju posle ponovljenog davanja 10 do 160 mg oksikodon hidrohlorida u 12-časovnim intervalima. Prijava sadrži još 22 zahteva.
YUP-2005/0411A 1992-11-25 1993-05-21 Komopzicije oksikodona sa kontrolisanim oslobađanjem RS50057B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1014692A 1992-11-25 1992-11-25

Publications (2)

Publication Number Publication Date
YU20050411A YU20050411A (sh) 2006-08-17
RS50057B true RS50057B (sr) 2008-11-28

Family

ID=37616752

Family Applications (2)

Application Number Title Priority Date Filing Date
YUP-2005/0411A RS50057B (sr) 1992-11-25 1993-05-21 Komopzicije oksikodona sa kontrolisanim oslobađanjem
YUP-2005/0413A RS50058B (sr) 1992-11-25 1993-05-21 Kompozicije oksikodona sa kontrolisanim oslobađanjem

Family Applications After (1)

Application Number Title Priority Date Filing Date
YUP-2005/0413A RS50058B (sr) 1992-11-25 1993-05-21 Kompozicije oksikodona sa kontrolisanim oslobađanjem

Country Status (2)

Country Link
ME (6) MEP47508A (sr)
RS (2) RS50057B (sr)

Also Published As

Publication number Publication date
RS50058B (sr) 2008-11-28
MEP47508A (en) 2011-02-10
MEP48008A (en) 2011-02-10
MEP47608A (en) 2011-02-10
MEP47708A (en) 2011-02-10
MEP47908A (en) 2011-02-10
MEP47808A (en) 2011-02-10
YU20050411A (sh) 2006-08-17
YU20050413A (sh) 2006-08-17

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