RS20050561A - HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONjUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS - Google Patents

HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONjUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS

Info

Publication number
RS20050561A
RS20050561A YUP-2005/0561A YUP20050561A RS20050561A RS 20050561 A RS20050561 A RS 20050561A YU P20050561 A YUP20050561 A YU P20050561A RS 20050561 A RS20050561 A RS 20050561A
Authority
RS
Serbia
Prior art keywords
biomolecules
conjugates
thiol
hydrophilic
dyes
Prior art date
Application number
YUP-2005/0561A
Other languages
English (en)
Inventor
Kai Licha
Christin Perlitz
Original Assignee
Schering Ag.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag., filed Critical Schering Ag.,
Priority claimed from PCT/EP2003/012735 external-priority patent/WO2004065491A1/en
Publication of RS20050561A publication Critical patent/RS20050561A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Pronalazak se odnosi na nove fluorescentne boje iz klase cijanin boja, posebno indotrikarbocijanine sa maksimumom absorbcije i fluorescencije u rasponu spektra od 700 do 900 nm, tiol-specifičnu reaktivnu grupu, i tri, pretpostavljeno četiri, sulfonat grupe, da se poveća rastvorljivost u vodi kao i proizvodnja boja. Ovaj pronalazak se takođe odnosi na konjugate ovih boja sa biomolekulima i njihove upotrebe
YUP-2005/0561A 2003-01-24 2003-11-14 HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONjUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS RS20050561A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2003102787 DE10302787A1 (de) 2003-01-24 2003-01-24 Hydrophile, Thiol-reaktive Cyaninfarbstoffe und deren Konjugate mit Biomolekülen für die Fluoreszenzdiagnostik
US44319703P 2003-01-29 2003-01-29
PCT/EP2003/012735 WO2004065491A1 (en) 2003-01-24 2003-11-14 Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis

Publications (1)

Publication Number Publication Date
RS20050561A true RS20050561A (en) 2007-09-21

Family

ID=32694952

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2005/0561A RS20050561A (en) 2003-01-24 2003-11-14 HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONjUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS

Country Status (6)

Country Link
CN (1) CN1742057A (sr)
DE (1) DE10302787A1 (sr)
NO (1) NO20053919L (sr)
RS (1) RS20050561A (sr)
UA (1) UA82684C2 (sr)
ZA (1) ZA200506759B (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012001043A2 (pt) * 2009-07-16 2016-03-15 Beckman Coulter Inc tinturas fluorescentes e uso das mesmas
EP3001197A1 (en) * 2014-09-23 2016-03-30 Universität Heidelberg Fluorescent protein stains
CN107488657A (zh) * 2017-08-15 2017-12-19 苏州泽科生物科技有限公司 核酸的活性染料偶联标记、检测及提纯方法
CN108192376A (zh) * 2018-01-09 2018-06-22 深圳大学 一种五甲川菁染料及制备方法
US10968386B2 (en) 2018-01-09 2021-04-06 Shenzhen University Pentamethine cyanine dye and preparation method therefor
CN108727245B (zh) * 2018-07-02 2021-09-28 广州中医药大学(广州中医药研究院) 一种水杨酸类化合物及其制备方法和应用
CN110201189B (zh) * 2019-06-03 2021-12-07 沈阳药科大学 白蛋白结合型近红外荧光染料-马来酰亚胺共轭物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225050B1 (en) * 1986-04-18 2001-05-01 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US6002503A (en) * 1997-10-23 1999-12-14 Ciena Corporation Optical add/drop multiplexer
US6217848B1 (en) * 1999-05-20 2001-04-17 Mallinckrodt Inc. Cyanine and indocyanine dye bioconjugates for biomedical applications
US6180085B1 (en) * 2000-01-18 2001-01-30 Mallinckrodt Inc. Dyes

Also Published As

Publication number Publication date
DE10302787A1 (de) 2004-08-12
NO20053919D0 (no) 2005-08-23
ZA200506759B (en) 2007-01-31
NO20053919L (no) 2005-10-24
CN1742057A (zh) 2006-03-01
UA82684C2 (uk) 2008-05-12

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