NO20053919L - Hydrofile tiol-reaktive cyaninfargestoffer og konjugater av disse med biomolekyler for fluorisensdiagnostikk. - Google Patents

Hydrofile tiol-reaktive cyaninfargestoffer og konjugater av disse med biomolekyler for fluorisensdiagnostikk.

Info

Publication number
NO20053919L
NO20053919L NO20053919A NO20053919A NO20053919L NO 20053919 L NO20053919 L NO 20053919L NO 20053919 A NO20053919 A NO 20053919A NO 20053919 A NO20053919 A NO 20053919A NO 20053919 L NO20053919 L NO 20053919L
Authority
NO
Norway
Prior art keywords
biomolecules
conjugates
dyes
cyanine dyes
fluorescence diagnostics
Prior art date
Application number
NO20053919A
Other languages
English (en)
Other versions
NO20053919D0 (no
Inventor
Kai Licha
Christin Perlitz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2003/012735 external-priority patent/WO2004065491A1/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20053919D0 publication Critical patent/NO20053919D0/no
Publication of NO20053919L publication Critical patent/NO20053919L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/0066—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of a carbocyclic ring,(e.g. benzene, naphtalene, cyclohexene, cyclobutenene-quadratic acid)
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
    • C09B23/08—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines
    • C09B23/086—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups more than three >CH- groups, e.g. polycarbocyanines more than five >CH- groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Denne oppfinnelsen vedrører nye fiuor-escensfargestoffer fra klassen av cyaninfarge-stoffer, spesielt indotrikarbocyaniner med et absorpsjons- og fluorescensmaksimum i spektral-området 700-900 nm, en tiolspesifikk reaktiv gruppe og tre, fortrinnsvis fire, sulfonatgrupper, for en økning av vannoppløselighet, samt fremstillingen av fargestoffer. Denne oppfinnelsen vedrører også konjugatene av disse fargestoffene med biomolekyler, og anvendelser derav.
NO20053919A 2003-01-24 2005-08-23 Hydrofile tiol-reaktive cyaninfargestoffer og konjugater av disse med biomolekyler for fluorisensdiagnostikk. NO20053919L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2003102787 DE10302787A1 (de) 2003-01-24 2003-01-24 Hydrophile, Thiol-reaktive Cyaninfarbstoffe und deren Konjugate mit Biomolekülen für die Fluoreszenzdiagnostik
PCT/EP2003/012735 WO2004065491A1 (en) 2003-01-24 2003-11-14 Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis

Publications (2)

Publication Number Publication Date
NO20053919D0 NO20053919D0 (no) 2005-08-23
NO20053919L true NO20053919L (no) 2005-10-24

Family

ID=32694952

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053919A NO20053919L (no) 2003-01-24 2005-08-23 Hydrofile tiol-reaktive cyaninfargestoffer og konjugater av disse med biomolekyler for fluorisensdiagnostikk.

Country Status (6)

Country Link
CN (1) CN1742057A (no)
DE (1) DE10302787A1 (no)
NO (1) NO20053919L (no)
RS (1) RS20050561A (no)
UA (1) UA82684C2 (no)
ZA (1) ZA200506759B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8367842B2 (en) * 2009-07-16 2013-02-05 Beckman Coulter, Inc. Fluorescent dyes and uses thereof
EP3001197A1 (en) * 2014-09-23 2016-03-30 Universität Heidelberg Fluorescent protein stains
CN107488657A (zh) * 2017-08-15 2017-12-19 苏州泽科生物科技有限公司 核酸的活性染料偶联标记、检测及提纯方法
US10968386B2 (en) 2018-01-09 2021-04-06 Shenzhen University Pentamethine cyanine dye and preparation method therefor
CN108192376A (zh) * 2018-01-09 2018-06-22 深圳大学 一种五甲川菁染料及制备方法
CN108727245B (zh) * 2018-07-02 2021-09-28 广州中医药大学(广州中医药研究院) 一种水杨酸类化合物及其制备方法和应用
CN110201189B (zh) * 2019-06-03 2021-12-07 沈阳药科大学 白蛋白结合型近红外荧光染料-马来酰亚胺共轭物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225050B1 (en) * 1986-04-18 2001-05-01 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US6002503A (en) * 1997-10-23 1999-12-14 Ciena Corporation Optical add/drop multiplexer
US6217848B1 (en) * 1999-05-20 2001-04-17 Mallinckrodt Inc. Cyanine and indocyanine dye bioconjugates for biomedical applications
US6180085B1 (en) * 2000-01-18 2001-01-30 Mallinckrodt Inc. Dyes

Also Published As

Publication number Publication date
DE10302787A1 (de) 2004-08-12
RS20050561A (en) 2007-09-21
ZA200506759B (en) 2007-01-31
UA82684C2 (uk) 2008-05-12
CN1742057A (zh) 2006-03-01
NO20053919D0 (no) 2005-08-23

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