RO88552A - Procedeu de obtinere a unei enzime fibrinolitice - Google Patents

Procedeu de obtinere a unei enzime fibrinolitice

Info

Publication number
RO88552A
RO88552A RO83112448A RO11244883A RO88552A RO 88552 A RO88552 A RO 88552A RO 83112448 A RO83112448 A RO 83112448A RO 11244883 A RO11244883 A RO 11244883A RO 88552 A RO88552 A RO 88552A
Authority
RO
Romania
Prior art keywords
pct
fibrinolithic
enzyme
obtaining
sec
Prior art date
Application number
RO83112448A
Other languages
English (en)
French (fr)
Inventor
Anthony Atkinson
Asgar Electricwala
John B Griffiths
Latteramy
Patrick A Riley
Original Assignee
Public Health Laboratory Service Board,Gb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Public Health Laboratory Service Board,Gb filed Critical Public Health Laboratory Service Board,Gb
Publication of RO88552A publication Critical patent/RO88552A/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/75Fibrin; Fibrinogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Neurosurgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RO83112448A 1982-03-05 1983-10-31 Procedeu de obtinere a unei enzime fibrinolitice RO88552A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8206576 1982-03-05

Publications (1)

Publication Number Publication Date
RO88552A true RO88552A (ro) 1986-02-28

Family

ID=10528816

Family Applications (1)

Application Number Title Priority Date Filing Date
RO83112448A RO88552A (ro) 1982-03-05 1983-10-31 Procedeu de obtinere a unei enzime fibrinolitice

Country Status (18)

Country Link
US (1) US4780412A (ro)
EP (1) EP0104194B1 (ro)
JP (1) JPS59500351A (ro)
AT (1) ATE32232T1 (ro)
AU (2) AU567491B2 (ro)
BR (1) BR8306108A (ro)
CA (1) CA1213231A (ro)
DE (1) DE3375491D1 (ro)
DK (1) DK163134C (ro)
FI (1) FI76375C (ro)
HU (1) HU200792B (ro)
IE (1) IE54593B1 (ro)
IT (1) IT1194148B (ro)
NO (1) NO161445C (ro)
RO (1) RO88552A (ro)
SU (1) SU1507204A3 (ro)
WO (1) WO1983003101A1 (ro)
ZA (1) ZA831399B (ro)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds
DE3582338D1 (de) * 1984-01-30 1991-05-08 Asahi Chemical Ind Verfahren zur herstellung eines doppelkettigen plasminogenaktivators.
JPS60158115A (ja) * 1984-01-30 1985-08-19 Meiji Milk Prod Co Ltd プラズミノーゲンアクチベーターの製造法
US4661453A (en) * 1984-06-19 1987-04-28 American Biogenetic Sciences, Inc. Production of tissue plasminogen activator factor
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
AT391812B (de) * 1985-05-28 1990-12-10 Wellcome Found Verfahren zur herstellung einer parenteralen t-pa-loesung
DE3722522A1 (de) * 1987-07-08 1989-01-19 Boehringer Ingelheim Int Verwendung eines vehikels mit hoher affinitaet zu tumoren
GB8723082D0 (en) * 1987-10-01 1987-11-04 Porton Prod Ltd Enzyme production
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
GB9000629D0 (en) * 1990-01-11 1990-03-14 Porton Prod Ltd Tissue plasminogen activator
IT1245485B (it) * 1991-05-03 1994-09-20 Butterfly Srl Membrane permselettive e loro impiego

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
IT1170913B (it) * 1981-04-23 1987-06-03 Manetti & Roberts Italo Brit Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
AU554862B2 (en) * 1982-12-14 1986-09-04 Implico B.V. Plasminogen activator isolated by affinity chromatography
NZ206699A (en) * 1982-12-30 1989-08-29 Bio Response Inc Process for the production of serum independent cell lines

Also Published As

Publication number Publication date
IT8319914A0 (it) 1983-03-04
WO1983003101A1 (en) 1983-09-15
FI834042A0 (fi) 1983-11-03
AU1214688A (en) 1988-09-08
IT1194148B (it) 1988-09-14
HU200792B (en) 1990-08-28
IE830480L (en) 1983-09-05
FI76375B (fi) 1988-06-30
IT8319914A1 (it) 1984-09-04
NO161445B (no) 1989-05-08
FI76375C (fi) 1988-10-10
US4780412A (en) 1988-10-25
ZA831399B (en) 1984-02-29
JPS59500351A (ja) 1984-03-08
ATE32232T1 (de) 1988-02-15
BR8306108A (pt) 1984-01-17
DK506683A (da) 1983-11-04
EP0104194B1 (en) 1988-01-27
FI834042L (fi) 1983-11-03
NO834024L (no) 1983-11-04
AU625283B2 (en) 1992-07-09
AU567491B2 (en) 1987-11-26
NO161445C (no) 1989-08-16
EP0104194A1 (en) 1984-04-04
DK163134B (da) 1992-01-20
IE54593B1 (en) 1989-12-06
DK163134C (da) 1992-06-09
AU1337783A (en) 1983-10-18
DE3375491D1 (en) 1988-03-03
SU1507204A3 (ru) 1989-09-07
DK506683D0 (da) 1983-11-04
CA1213231A (en) 1986-10-28

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