RO86851B - Procedeu pentru prepararea unor derivati de piperazin-2-ona - Google Patents
Procedeu pentru prepararea unor derivati de piperazin-2-onaInfo
- Publication number
- RO86851B RO86851B RO111170A RO11117083A RO86851B RO 86851 B RO86851 B RO 86851B RO 111170 A RO111170 A RO 111170A RO 11117083 A RO11117083 A RO 11117083A RO 86851 B RO86851 B RO 86851B
- Authority
- RO
- Romania
- Prior art keywords
- general formula
- hydrogen
- sodium
- compound
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8216437 | 1982-06-05 | ||
| GB838300476A GB8300476D0 (en) | 1983-01-08 | 1983-01-08 | Heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO86851A RO86851A (ro) | 1985-05-20 |
| RO86851B true RO86851B (ro) | 1985-05-31 |
Family
ID=26283037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO111170A RO86851B (ro) | 1982-06-05 | 1983-06-03 | Procedeu pentru prepararea unor derivati de piperazin-2-ona |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4556711A (OSRAM) |
| EP (1) | EP0096517A3 (OSRAM) |
| KR (1) | KR840005111A (OSRAM) |
| AU (1) | AU1527583A (OSRAM) |
| DD (1) | DD209818A5 (OSRAM) |
| DK (1) | DK247783A (OSRAM) |
| ES (2) | ES522962A0 (OSRAM) |
| FI (1) | FI831998A7 (OSRAM) |
| GR (1) | GR79299B (OSRAM) |
| JO (1) | JO1255B1 (OSRAM) |
| NO (1) | NO832016L (OSRAM) |
| PL (1) | PL242354A1 (OSRAM) |
| PT (1) | PT76791B (OSRAM) |
| RO (1) | RO86851B (OSRAM) |
| ZW (1) | ZW12783A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
| GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| US4595766A (en) * | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
| US4697016A (en) * | 1984-10-26 | 1987-09-29 | Ciba-Geigy Corporation | Intermediates for the preparation of a carboxylic acid |
| JPS62198671A (ja) * | 1986-02-25 | 1987-09-02 | Toyo Jozo Co Ltd | １−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| EA020466B1 (ru) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний |
| EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US20130035326A1 (en) * | 2009-08-19 | 2013-02-07 | Ambit Biosciences Corporation | Biaryl compounds and methods of use thereof |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CA3100941C (en) | 2011-03-01 | 2024-03-05 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
| CA2874953A1 (en) * | 2012-06-12 | 2013-12-19 | Abbvie Inc. | Pyridinone and pyridazinone derivatives |
| EP3718557A3 (en) | 2013-02-25 | 2020-10-21 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing |
| WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法 |
| CN114404588A (zh) | 2013-08-09 | 2022-04-29 | 阿德利克斯公司 | 用于抑制磷酸盐转运的化合物和方法 |
| CN114340631A (zh) | 2019-05-21 | 2022-04-12 | 阿德利克斯股份有限公司 | 用于降低患者的血清磷酸盐的组合 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
-
1983
- 1983-05-27 EP EP83303059A patent/EP0096517A3/en not_active Withdrawn
- 1983-06-01 AU AU15275/83A patent/AU1527583A/en not_active Abandoned
- 1983-06-01 GR GR71530A patent/GR79299B/el unknown
- 1983-06-01 PT PT76791A patent/PT76791B/pt unknown
- 1983-06-01 JO JO19831255A patent/JO1255B1/en active
- 1983-06-01 DK DK247783A patent/DK247783A/da not_active Application Discontinuation
- 1983-06-02 US US06/500,486 patent/US4556711A/en not_active Expired - Lifetime
- 1983-06-02 US US06/500,484 patent/US4514568A/en not_active Expired - Fee Related
- 1983-06-03 FI FI831998A patent/FI831998A7/fi not_active Application Discontinuation
- 1983-06-03 RO RO111170A patent/RO86851B/ro unknown
- 1983-06-03 DD DD25173683A patent/DD209818A5/de unknown
- 1983-06-03 NO NO832016A patent/NO832016L/no unknown
- 1983-06-03 PL PL24235483A patent/PL242354A1/xx unknown
- 1983-06-03 ES ES522962A patent/ES522962A0/es active Granted
- 1983-06-03 ZW ZW127/83A patent/ZW12783A1/xx unknown
- 1983-06-04 KR KR1019830002511A patent/KR840005111A/ko not_active Withdrawn
-
1984
- 1984-02-24 ES ES530024A patent/ES8707507A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| RO86851A (ro) | 1985-05-20 |
| PT76791B (en) | 1986-01-24 |
| GR79299B (OSRAM) | 1984-10-22 |
| US4514568A (en) | 1985-04-30 |
| ES8500244A1 (es) | 1984-10-01 |
| FI831998L (fi) | 1983-12-06 |
| FI831998A0 (fi) | 1983-06-03 |
| PT76791A (en) | 1983-07-01 |
| ES530024A0 (es) | 1985-12-01 |
| ZW12783A1 (en) | 1983-08-24 |
| KR840005111A (ko) | 1984-11-03 |
| DD209818A5 (de) | 1984-05-23 |
| DK247783A (da) | 1983-12-06 |
| EP0096517A2 (en) | 1983-12-21 |
| PL242354A1 (en) | 1984-12-17 |
| US4556711A (en) | 1985-12-03 |
| EP0096517A3 (en) | 1985-04-03 |
| NO832016L (no) | 1983-12-06 |
| ES522962A0 (es) | 1984-10-01 |
| JO1255B1 (en) | 1985-04-20 |
| ES8707507A1 (es) | 1985-12-01 |
| AU1527583A (en) | 1983-12-08 |
| FI831998A7 (fi) | 1983-12-06 |
| DK247783D0 (da) | 1983-06-01 |
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