FI831998A7 - Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. - Google Patents
Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. Download PDFInfo
- Publication number
- FI831998A7 FI831998A7 FI831998A FI831998A FI831998A7 FI 831998 A7 FI831998 A7 FI 831998A7 FI 831998 A FI831998 A FI 831998A FI 831998 A FI831998 A FI 831998A FI 831998 A7 FI831998 A7 FI 831998A7
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- pharmaceutically active
- pyrazinone derivatives
- pyrazinone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8216437 | 1982-06-05 | ||
| GB838300476A GB8300476D0 (en) | 1983-01-08 | 1983-01-08 | Heterocyclic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI831998A0 FI831998A0 (fi) | 1983-06-03 |
| FI831998L FI831998L (fi) | 1983-12-06 |
| FI831998A7 true FI831998A7 (fi) | 1983-12-06 |
Family
ID=26283037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI831998A FI831998A7 (fi) | 1982-06-05 | 1983-06-03 | Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4556711A (OSRAM) |
| EP (1) | EP0096517A3 (OSRAM) |
| KR (1) | KR840005111A (OSRAM) |
| AU (1) | AU1527583A (OSRAM) |
| DD (1) | DD209818A5 (OSRAM) |
| DK (1) | DK247783A (OSRAM) |
| ES (2) | ES522962A0 (OSRAM) |
| FI (1) | FI831998A7 (OSRAM) |
| GR (1) | GR79299B (OSRAM) |
| JO (1) | JO1255B1 (OSRAM) |
| NO (1) | NO832016L (OSRAM) |
| PL (1) | PL242354A1 (OSRAM) |
| PT (1) | PT76791B (OSRAM) |
| RO (1) | RO86851B (OSRAM) |
| ZW (1) | ZW12783A1 (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
| GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| US4697016A (en) * | 1984-10-26 | 1987-09-29 | Ciba-Geigy Corporation | Intermediates for the preparation of a carboxylic acid |
| US4595766A (en) * | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
| JPS62198671A (ja) * | 1986-02-25 | 1987-09-02 | Toyo Jozo Co Ltd | １−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| ES2559319T3 (es) | 2007-06-04 | 2016-02-11 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato cliclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| JP2013502429A (ja) * | 2009-08-19 | 2013-01-24 | アムビト ビオスシエンセス コルポラチオン | ビアリール化合物及びその使用方法 |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| DK2681236T3 (en) | 2011-03-01 | 2018-04-16 | Synergy Pharmaceuticals Inc | PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS |
| RU2632915C2 (ru) | 2012-06-12 | 2017-10-11 | Эббви Инк. | Производные пиридинона и пиридазинона |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| WO2014197720A2 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
| CN105979959B (zh) | 2013-08-09 | 2021-11-30 | 阿德利克斯公司 | 用于抑制磷酸盐转运的化合物和方法 |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
-
1983
- 1983-05-27 EP EP83303059A patent/EP0096517A3/en not_active Withdrawn
- 1983-06-01 DK DK247783A patent/DK247783A/da not_active Application Discontinuation
- 1983-06-01 PT PT76791A patent/PT76791B/pt unknown
- 1983-06-01 AU AU15275/83A patent/AU1527583A/en not_active Abandoned
- 1983-06-01 GR GR71530A patent/GR79299B/el unknown
- 1983-06-01 JO JO19831255A patent/JO1255B1/en active
- 1983-06-02 US US06/500,486 patent/US4556711A/en not_active Expired - Lifetime
- 1983-06-02 US US06/500,484 patent/US4514568A/en not_active Expired - Fee Related
- 1983-06-03 NO NO832016A patent/NO832016L/no unknown
- 1983-06-03 DD DD25173683A patent/DD209818A5/de unknown
- 1983-06-03 ZW ZW127/83A patent/ZW12783A1/xx unknown
- 1983-06-03 RO RO111170A patent/RO86851B/ro unknown
- 1983-06-03 ES ES522962A patent/ES522962A0/es active Granted
- 1983-06-03 PL PL24235483A patent/PL242354A1/xx unknown
- 1983-06-03 FI FI831998A patent/FI831998A7/fi not_active Application Discontinuation
- 1983-06-04 KR KR1019830002511A patent/KR840005111A/ko not_active Withdrawn
-
1984
- 1984-02-24 ES ES530024A patent/ES530024A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8707507A1 (es) | 1985-12-01 |
| KR840005111A (ko) | 1984-11-03 |
| PT76791B (en) | 1986-01-24 |
| FI831998L (fi) | 1983-12-06 |
| EP0096517A2 (en) | 1983-12-21 |
| AU1527583A (en) | 1983-12-08 |
| FI831998A0 (fi) | 1983-06-03 |
| GR79299B (OSRAM) | 1984-10-22 |
| JO1255B1 (en) | 1985-04-20 |
| DD209818A5 (de) | 1984-05-23 |
| DK247783A (da) | 1983-12-06 |
| RO86851A (ro) | 1985-05-20 |
| RO86851B (ro) | 1985-05-31 |
| ES8500244A1 (es) | 1984-10-01 |
| ES530024A0 (es) | 1985-12-01 |
| PL242354A1 (en) | 1984-12-17 |
| US4514568A (en) | 1985-04-30 |
| ZW12783A1 (en) | 1983-08-24 |
| US4556711A (en) | 1985-12-03 |
| PT76791A (en) | 1983-07-01 |
| DK247783D0 (da) | 1983-06-01 |
| ES522962A0 (es) | 1984-10-01 |
| EP0096517A3 (en) | 1985-04-03 |
| NO832016L (no) | 1983-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn [patent] |
Owner name: SMITH KLINE & FRENCH LABORATORIES |