RO82014A - Procedeu pentru prepararea unor derivati de 4-chinolina cu activitateantihipertensiva - Google Patents
Procedeu pentru prepararea unor derivati de 4-chinolina cu activitateantihipertensivaInfo
- Publication number
- RO82014A RO82014A RO81105404A RO10540481A RO82014A RO 82014 A RO82014 A RO 82014A RO 81105404 A RO81105404 A RO 81105404A RO 10540481 A RO10540481 A RO 10540481A RO 82014 A RO82014 A RO 82014A
- Authority
- RO
- Romania
- Prior art keywords
- preparation
- quinolone derivatives
- antihypertensive action
- antihypertensive
- quinolone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8031106 | 1980-09-26 | ||
| GB8031162 | 1980-09-26 | ||
| GB8119062 | 1981-06-19 | ||
| GB8118879 | 1981-06-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO82014B RO82014B (ro) | 1983-05-30 |
| RO82014A true RO82014A (ro) | 1983-06-01 |
Family
ID=27449208
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO110630A RO85318B (ro) | 1980-09-26 | 1981-09-25 | Procedeu pentru prepararea unor derivati de 4-chinolona cu activitate antihipertensiva |
| RO81105404A RO82014A (ro) | 1980-09-26 | 1981-09-25 | Procedeu pentru prepararea unor derivati de 4-chinolina cu activitateantihipertensiva |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO110630A RO85318B (ro) | 1980-09-26 | 1981-09-25 | Procedeu pentru prepararea unor derivati de 4-chinolona cu activitate antihipertensiva |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US4442109A (ro) |
| AT (1) | AT379388B (ro) |
| AU (1) | AU549078B2 (ro) |
| BG (2) | BG36344A3 (ro) |
| CA (1) | CA1146943A (ro) |
| CH (1) | CH650254A5 (ro) |
| DD (1) | DD201890A5 (ro) |
| DE (1) | DE3138121A1 (ro) |
| DK (1) | DK152674C (ro) |
| ES (2) | ES505786A0 (ro) |
| FI (1) | FI812997L (ro) |
| FR (1) | FR2491064A1 (ro) |
| GR (1) | GR75797B (ro) |
| IE (1) | IE51542B1 (ro) |
| IL (1) | IL63845A (ro) |
| IT (1) | IT1189449B (ro) |
| LU (1) | LU83649A1 (ro) |
| NL (1) | NL8104394A (ro) |
| NO (1) | NO154052C (ro) |
| NZ (1) | NZ198414A (ro) |
| PH (1) | PH18605A (ro) |
| PT (1) | PT73666B (ro) |
| RO (2) | RO85318B (ro) |
| SE (1) | SE457533B (ro) |
| YU (2) | YU230181A (ro) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT79031B (en) * | 1983-08-20 | 1986-08-22 | Boots Co Plc | Therapeutic agents |
| EP0149519B1 (en) * | 1984-01-13 | 1990-06-27 | The Boots Company PLC | Use of quinolones for the manufacture of a composition for the treatment of heart failure. |
| DE3576686D1 (de) * | 1984-08-15 | 1990-04-26 | Boots Co Ltd | Chinolinone, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen praeparate. |
| GB8515207D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
| GB8515209D0 (en) * | 1985-06-15 | 1985-07-17 | Boots Co Plc | Therapeutic agents |
| GB8627698D0 (en) * | 1986-11-20 | 1986-12-17 | Boots Co Plc | Therapeutic agents |
| GB8726950D0 (en) * | 1987-11-18 | 1987-12-23 | Boots Co Plc | Chemical process |
| GB8804016D0 (en) * | 1988-02-22 | 1988-03-23 | Boots Co Plc | Therapeutic agents |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3121725A (en) * | 1960-07-18 | 1964-02-18 | Phillips Petroleum Co | N-heterocyclic sulfides, sulfoxides, sulfones, and n-oxides of said sulfoxides and sulfones |
| US3801644A (en) * | 1971-08-25 | 1974-04-02 | Warner Lambert Co | Substituted-o-hydroxy-omega-(methylsulfinyl)acetophenones and process for producing same |
| US3772301A (en) * | 1971-11-22 | 1973-11-13 | Warner Lambert Co | (4-substituted)4-(methylsulfinyl)methylcarbostyrils |
| US4343805A (en) * | 1978-12-16 | 1982-08-10 | John Wyeth & Brother Limited | Heterocyclic compounds |
| GB2038825B (en) * | 1978-12-16 | 1983-02-09 | Wyeth John & Brother Ltd | Heterocyclic compounds substituted by heterocyclyl-alkyl-thio groups |
| ZA801575B (en) * | 1979-03-27 | 1981-03-25 | Boots Co Ltd | Therapeutic agents |
| NZ193167A (en) * | 1979-03-27 | 1984-08-24 | Boots Co Plc | Quinoline derivatives and pharmaceutical compositions |
| US4302360A (en) * | 1980-01-11 | 1981-11-24 | Agency Of Industrial Science & Technology | Catalyst for catalytic combustion of hydrogen |
-
1981
- 1981-09-02 IE IE2033/81A patent/IE51542B1/en unknown
- 1981-09-14 PT PT73666A patent/PT73666B/pt unknown
- 1981-09-14 PH PH26202A patent/PH18605A/en unknown
- 1981-09-16 IL IL63845A patent/IL63845A/xx unknown
- 1981-09-18 GR GR66095A patent/GR75797B/el unknown
- 1981-09-18 FR FR8117630A patent/FR2491064A1/fr active Granted
- 1981-09-21 US US06/303,948 patent/US4442109A/en not_active Expired - Fee Related
- 1981-09-21 AU AU75524/81A patent/AU549078B2/en not_active Ceased
- 1981-09-21 US US06/304,165 patent/US4447435A/en not_active Expired - Fee Related
- 1981-09-21 NZ NZ198414A patent/NZ198414A/xx unknown
- 1981-09-23 BG BG8153612A patent/BG36344A3/xx unknown
- 1981-09-23 CA CA000386485A patent/CA1146943A/en not_active Expired
- 1981-09-23 BG BG8362845A patent/BG36495A3/xx unknown
- 1981-09-24 DE DE19813138121 patent/DE3138121A1/de not_active Ceased
- 1981-09-24 LU LU83649A patent/LU83649A1/fr unknown
- 1981-09-24 YU YU02301/81A patent/YU230181A/xx unknown
- 1981-09-24 NL NL8104394A patent/NL8104394A/nl not_active Application Discontinuation
- 1981-09-25 SE SE8105689A patent/SE457533B/sv not_active IP Right Cessation
- 1981-09-25 NO NO813263A patent/NO154052C/no unknown
- 1981-09-25 FI FI812997A patent/FI812997L/fi not_active Application Discontinuation
- 1981-09-25 ES ES505786A patent/ES505786A0/es active Granted
- 1981-09-25 RO RO110630A patent/RO85318B/ro unknown
- 1981-09-25 AT AT0412181A patent/AT379388B/de not_active IP Right Cessation
- 1981-09-25 RO RO81105404A patent/RO82014A/ro unknown
- 1981-09-25 CH CH6235/81A patent/CH650254A5/fr not_active IP Right Cessation
- 1981-09-25 DK DK424781A patent/DK152674C/da active
- 1981-09-25 IT IT49370/81A patent/IT1189449B/it active
- 1981-09-28 DD DD81233630A patent/DD201890A5/de unknown
-
1982
- 1982-07-27 ES ES514411A patent/ES8306111A1/es not_active Expired
-
1983
- 1983-07-01 YU YU01446/83A patent/YU144683A/xx unknown
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