|
US4464467A
(en)
*
|
1982-07-26 |
1984-08-07 |
Bristol-Myers Company |
Antitumor antibiotics produced by new streptomyces
|
|
ES2244210T3
(es)
|
1998-08-27 |
2005-12-01 |
Spirogen Limited |
Pirrolobenzodiazepinas.
|
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
PT2270010E
(pt)
|
2004-03-01 |
2012-03-12 |
Spirogen Ltd |
Derivados de 11-hidroxi-5h-pirrolo[2,1-c][1,4]benzodiazepin- 5-ona como intermediários chave para a preparação de pirrolobenzodiazepinas substituídas em c2
|
|
EP1723152B1
(en)
|
2004-03-09 |
2015-02-11 |
Spirogen Sàrl |
Pyrrolobenzodiazepines
|
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
EP2558475A1
(en)
|
2010-04-15 |
2013-02-20 |
Spirogen Sàrl |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
|
MX2012011900A
(es)
|
2010-04-15 |
2013-03-21 |
Seattle Genetics Inc |
Conjugados de pirrolobenzodiazepina diana.
|
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
|
KR101860174B1
(ko)
|
2011-09-20 |
2018-05-21 |
메디뮨 리미티드 |
표적 접합체 내의 내포를 위한 비대칭 이량체 pbd 화합물로서 피롤로벤조디아제핀
|
|
BR112014009070B1
(pt)
|
2011-10-14 |
2021-11-23 |
Medimmune Limited |
Método de síntese e intermediários úteis na preparação de pirrolobenzo-diazepinas
|
|
CN103997893B
(zh)
|
2011-10-14 |
2019-04-12 |
西雅图基因公司 |
吡咯并苯并二氮杂卓和靶向结合物
|
|
BR112014008888A2
(pt)
|
2011-10-14 |
2017-04-18 |
Seattle Genetics Inc |
pirrolobenzodiazepinas
|
|
CN103998449A
(zh)
|
2011-10-14 |
2014-08-20 |
斯皮罗根有限公司 |
吡咯并苯并二氮杂卓
|
|
CN103987384A
(zh)
|
2011-10-14 |
2014-08-13 |
西雅图基因公司 |
吡咯并苯并二氮杂卓和靶向结合物
|
|
HRP20171916T1
(hr)
|
2012-10-12 |
2018-02-09 |
Adc Therapeutics Sa |
Konjugati protutijelo anti-cd22 - pirolobenzodiazepin
|
|
CA2885340C
(en)
|
2012-10-12 |
2016-11-08 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
HRP20181646T2
(hr)
|
2012-10-12 |
2019-08-09 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin - anti-psma protutijela
|
|
JP6367204B2
(ja)
|
2012-10-12 |
2018-08-01 |
メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ |
結合用のピロロベンゾジアゼピン誘導体の合成および中間体
|
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US9931415B2
(en)
|
2012-10-12 |
2018-04-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10736903B2
(en)
|
2012-10-12 |
2020-08-11 |
Medimmune Limited |
Pyrrolobenzodiazepine-anti-PSMA antibody conjugates
|
|
PT3470086T
(pt)
|
2012-10-12 |
2021-02-01 |
Medimmune Ltd |
Pirrolobenzodiazepinas e conjugados das mesmas
|
|
SMT201900017T1
(it)
|
2012-10-12 |
2019-02-28 |
Medimmune Ltd |
Coniugati pirrolobenzodiazepina-anticorpo
|
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054986B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
CA2968447A1
(en)
|
2014-11-25 |
2016-06-02 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates and their use to treat neoplasms
|
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
|
MX375569B
(es)
|
2017-02-08 |
2025-03-04 |
Adc Therapeutics Sa |
Conjugados de pirrolobenzodiazepinas y anticuerpos
|
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
|
SI3612537T1
(sl)
|
2017-04-18 |
2022-10-28 |
Medimmune Limited |
Konjugati pirolobenzodiazepina
|
|
JP7408396B2
(ja)
|
2017-04-20 |
2024-01-05 |
アーデーセー セラピューティクス ソシエテ アノニム |
併用療法
|
|
BR112019026564A2
(pt)
|
2017-06-14 |
2020-06-30 |
Adc Therapeutics Sa |
regimes de dosagem para a administração de um adc anti-cd19
|
|
KR102312910B1
(ko)
|
2017-08-18 |
2021-10-15 |
메디뮨 리미티드 |
피롤로벤조디아제핀 컨쥬게이트
|
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
|
SG11202108900WA
(en)
|
2019-03-15 |
2021-09-29 |
Medimmune Ltd |
Azetidobenzodiazepine dimers and conjugates comprising them for use in the treatment of cancer
|