RO120919B1 - Proteină hematopoietină, moleculă de acid nucleiccare o codifică, compoziţie farmaceutică şi utilizarea proteinei - Google Patents
Proteină hematopoietină, moleculă de acid nucleiccare o codifică, compoziţie farmaceutică şi utilizarea proteinei Download PDFInfo
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- 230000002936 tranquilizing effect Effects 0.000 description 1
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- 229960005356 urokinase Drugs 0.000 description 1
- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2962996P | 1996-10-25 | 1996-10-25 | |
| PCT/US1997/020037 WO1998017810A2 (en) | 1996-10-25 | 1997-10-23 | Multi-functional chimeric hematopoietic receptor agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RO120919B1 true RO120919B1 (ro) | 2006-09-29 |
Family
ID=21850035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO99-00480A RO120919B1 (ro) | 1996-10-25 | 1997-10-23 | Proteină hematopoietină, moleculă de acid nucleiccare o codifică, compoziţie farmaceutică şi utilizarea proteinei |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0935663A2 (de) |
| JP (1) | JP2001504689A (de) |
| KR (1) | KR100497423B1 (de) |
| AR (1) | AR010041A1 (de) |
| AU (1) | AU725547B2 (de) |
| BR (1) | BR9713668A (de) |
| CA (1) | CA2268742A1 (de) |
| CZ (1) | CZ295843B6 (de) |
| IL (1) | IL129565A0 (de) |
| NO (1) | NO991948L (de) |
| NZ (1) | NZ335382A (de) |
| PL (1) | PL333023A1 (de) |
| RO (1) | RO120919B1 (de) |
| RU (2) | RU2245887C2 (de) |
| TW (2) | TW591035B (de) |
| WO (1) | WO1998017810A2 (de) |
| ZA (1) | ZA979607B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5581476A (en) | 1993-01-28 | 1996-12-03 | Amgen Inc. | Computer-based methods and articles of manufacture for preparing G-CSF analogs |
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| NZ337911A (en) * | 1997-04-11 | 2001-04-27 | G | flt3 ligand chimeric proteins |
| BR9905867A (pt) * | 1998-11-06 | 2001-01-23 | Bio Sidus S A | Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula |
| WO2002101047A1 (en) * | 2001-06-12 | 2002-12-19 | Smithkline Beecham Corporation | Method of identifying compounds that modulate epo primary response gene 1, eprg1, activities |
| WO2003006501A2 (en) | 2001-07-11 | 2003-01-23 | Maxygen Holdings, Ltd. | G-csf conjugates |
| WO2005047461A2 (en) | 2003-08-18 | 2005-05-26 | The Regents Of The University Of California | Polypeptide display libraries and methods of making and using thereof |
| EP1888119B1 (de) | 2005-06-01 | 2011-03-09 | Maxygen, Inc. | Pegylierte g-csf-polypeptide und herstellungsverfahren dafür |
| US7550433B2 (en) * | 2005-06-03 | 2009-06-23 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| EP3181575B1 (de) | 2005-08-31 | 2021-03-17 | The Regents of The University of California | Zelluläre peptidsequenzbibliotheken (clips) und verfahren zur verwendung davon |
| WO2007098548A1 (en) * | 2006-03-01 | 2007-09-07 | Apollo Life Sciences Limited | A molecule and chimeric molecules thereof |
| US8293685B2 (en) | 2007-07-26 | 2012-10-23 | The Regents Of The University Of California | Methods for enhancing bacterial cell display of proteins and peptides |
| US10071109B2 (en) | 2013-11-06 | 2018-09-11 | Molecular Templates, Inc. | Predictive biomarker for hypoxia-activated prodrug therapy |
| US20220185857A1 (en) * | 2019-03-28 | 2022-06-16 | Orionis Biosciences, Inc. | Fms-like tyrosine kinase 3 ligand (flt3l)-based chimeric proteins |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2069746A1 (en) * | 1990-09-28 | 1992-03-29 | Jonathan I. Rosen | Hybrid growth factors |
| US5376367A (en) * | 1991-11-22 | 1994-12-27 | Immunex Corporation | Fusion proteins comprising MGF and IL-3 |
| US6057133A (en) * | 1992-11-24 | 2000-05-02 | G. D. Searle | Multivariant human IL-3 fusion proteins and their recombinant production |
| US5738849A (en) * | 1992-11-24 | 1998-04-14 | G. D. Searle & Co. | Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them |
| US5635599A (en) * | 1994-04-08 | 1997-06-03 | The United States Of America As Represented By The Department Of Health And Human Services | Fusion proteins comprising circularly permuted ligands |
-
1997
- 1997-10-23 EP EP97946495A patent/EP0935663A2/de not_active Withdrawn
- 1997-10-23 KR KR10-1999-7003635A patent/KR100497423B1/ko not_active Expired - Fee Related
- 1997-10-23 RU RU99111071/13A patent/RU2245887C2/ru not_active IP Right Cessation
- 1997-10-23 CA CA002268742A patent/CA2268742A1/en not_active Abandoned
- 1997-10-23 RO RO99-00480A patent/RO120919B1/ro unknown
- 1997-10-23 PL PL97333023A patent/PL333023A1/xx unknown
- 1997-10-23 CZ CZ19991323A patent/CZ295843B6/cs not_active IP Right Cessation
- 1997-10-23 AU AU51652/98A patent/AU725547B2/en not_active Ceased
- 1997-10-23 NZ NZ335382A patent/NZ335382A/xx unknown
- 1997-10-23 WO PCT/US1997/020037 patent/WO1998017810A2/en not_active Ceased
- 1997-10-23 JP JP51975498A patent/JP2001504689A/ja not_active Abandoned
- 1997-10-23 IL IL12956597A patent/IL129565A0/xx unknown
- 1997-10-23 BR BR9713668-9A patent/BR9713668A/pt not_active Application Discontinuation
- 1997-10-27 TW TW086116018A patent/TW591035B/zh not_active IP Right Cessation
- 1997-10-27 ZA ZA979607A patent/ZA979607B/xx unknown
- 1997-10-27 TW TW093111460A patent/TW200413407A/zh unknown
- 1997-10-28 AR ARP970104979A patent/AR010041A1/es unknown
-
1999
- 1999-04-23 NO NO991948A patent/NO991948L/no not_active Application Discontinuation
-
2005
- 2005-02-24 RU RU2005105360/13A patent/RU2005105360A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2268742A1 (en) | 1998-04-30 |
| NO991948D0 (no) | 1999-04-23 |
| PL333023A1 (en) | 1999-11-08 |
| NZ335382A (en) | 2001-03-30 |
| IL129565A0 (en) | 2000-02-29 |
| BR9713668A (pt) | 2000-03-08 |
| RU2245887C2 (ru) | 2005-02-10 |
| KR20000052812A (ko) | 2000-08-25 |
| TW200413407A (en) | 2004-08-01 |
| ZA979607B (en) | 1999-04-28 |
| AU5165298A (en) | 1998-05-15 |
| EP0935663A2 (de) | 1999-08-18 |
| TW591035B (en) | 2004-06-11 |
| AR010041A1 (es) | 2000-05-17 |
| JP2001504689A (ja) | 2001-04-10 |
| KR100497423B1 (ko) | 2005-07-07 |
| AU725547B2 (en) | 2000-10-12 |
| WO1998017810A3 (en) | 1998-10-15 |
| WO1998017810A2 (en) | 1998-04-30 |
| NO991948L (no) | 1999-06-23 |
| CZ132399A3 (cs) | 1999-12-15 |
| RU2005105360A (ru) | 2006-08-10 |
| CZ295843B6 (cs) | 2005-11-16 |
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