NO991948L - Multifunksjonelle kimere hematopoetiske reseptoragonister - Google Patents

Multifunksjonelle kimere hematopoetiske reseptoragonister

Info

Publication number
NO991948L
NO991948L NO991948A NO991948A NO991948L NO 991948 L NO991948 L NO 991948L NO 991948 A NO991948 A NO 991948A NO 991948 A NO991948 A NO 991948A NO 991948 L NO991948 L NO 991948L
Authority
NO
Norway
Prior art keywords
receptor agonists
hematopoietic receptor
chimeric hematopoietic
multifunctional chimeric
multifunctional
Prior art date
Application number
NO991948A
Other languages
English (en)
Norwegian (no)
Other versions
NO991948D0 (no
Inventor
Charles A Mcwherter
Yiqing Feng
John P Mckearn
Neena L Summers
Nicholas R Staten
Philip R Streeter
John C Minnerly
Nancy I Minster
Susan L Woulfe
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO991948D0 publication Critical patent/NO991948D0/no
Publication of NO991948L publication Critical patent/NO991948L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO991948A 1996-10-25 1999-04-23 Multifunksjonelle kimere hematopoetiske reseptoragonister NO991948L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2962996P 1996-10-25 1996-10-25
PCT/US1997/020037 WO1998017810A2 (en) 1996-10-25 1997-10-23 Multi-functional chimeric hematopoietic receptor agonists

Publications (2)

Publication Number Publication Date
NO991948D0 NO991948D0 (no) 1999-04-23
NO991948L true NO991948L (no) 1999-06-23

Family

ID=21850035

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991948A NO991948L (no) 1996-10-25 1999-04-23 Multifunksjonelle kimere hematopoetiske reseptoragonister

Country Status (17)

Country Link
EP (1) EP0935663A2 (de)
JP (1) JP2001504689A (de)
KR (1) KR100497423B1 (de)
AR (1) AR010041A1 (de)
AU (1) AU725547B2 (de)
BR (1) BR9713668A (de)
CA (1) CA2268742A1 (de)
CZ (1) CZ295843B6 (de)
IL (1) IL129565A0 (de)
NO (1) NO991948L (de)
NZ (1) NZ335382A (de)
PL (1) PL333023A1 (de)
RO (1) RO120919B1 (de)
RU (2) RU2245887C2 (de)
TW (2) TW591035B (de)
WO (1) WO1998017810A2 (de)
ZA (1) ZA979607B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
NZ337911A (en) * 1997-04-11 2001-04-27 G flt3 ligand chimeric proteins
BR9905867A (pt) * 1998-11-06 2001-01-23 Bio Sidus S A Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula
WO2002101047A1 (en) * 2001-06-12 2002-12-19 Smithkline Beecham Corporation Method of identifying compounds that modulate epo primary response gene 1, eprg1, activities
WO2003006501A2 (en) 2001-07-11 2003-01-23 Maxygen Holdings, Ltd. G-csf conjugates
WO2005047461A2 (en) 2003-08-18 2005-05-26 The Regents Of The University Of California Polypeptide display libraries and methods of making and using thereof
EP1888119B1 (de) 2005-06-01 2011-03-09 Maxygen, Inc. Pegylierte g-csf-polypeptide und herstellungsverfahren dafür
US7550433B2 (en) * 2005-06-03 2009-06-23 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
EP3181575B1 (de) 2005-08-31 2021-03-17 The Regents of The University of California Zelluläre peptidsequenzbibliotheken (clips) und verfahren zur verwendung davon
WO2007098548A1 (en) * 2006-03-01 2007-09-07 Apollo Life Sciences Limited A molecule and chimeric molecules thereof
US8293685B2 (en) 2007-07-26 2012-10-23 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
US10071109B2 (en) 2013-11-06 2018-09-11 Molecular Templates, Inc. Predictive biomarker for hypoxia-activated prodrug therapy
US20220185857A1 (en) * 2019-03-28 2022-06-16 Orionis Biosciences, Inc. Fms-like tyrosine kinase 3 ligand (flt3l)-based chimeric proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2069746A1 (en) * 1990-09-28 1992-03-29 Jonathan I. Rosen Hybrid growth factors
US5376367A (en) * 1991-11-22 1994-12-27 Immunex Corporation Fusion proteins comprising MGF and IL-3
US6057133A (en) * 1992-11-24 2000-05-02 G. D. Searle Multivariant human IL-3 fusion proteins and their recombinant production
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US5635599A (en) * 1994-04-08 1997-06-03 The United States Of America As Represented By The Department Of Health And Human Services Fusion proteins comprising circularly permuted ligands

Also Published As

Publication number Publication date
CA2268742A1 (en) 1998-04-30
NO991948D0 (no) 1999-04-23
PL333023A1 (en) 1999-11-08
NZ335382A (en) 2001-03-30
IL129565A0 (en) 2000-02-29
RO120919B1 (ro) 2006-09-29
BR9713668A (pt) 2000-03-08
RU2245887C2 (ru) 2005-02-10
KR20000052812A (ko) 2000-08-25
TW200413407A (en) 2004-08-01
ZA979607B (en) 1999-04-28
AU5165298A (en) 1998-05-15
EP0935663A2 (de) 1999-08-18
TW591035B (en) 2004-06-11
AR010041A1 (es) 2000-05-17
JP2001504689A (ja) 2001-04-10
KR100497423B1 (ko) 2005-07-07
AU725547B2 (en) 2000-10-12
WO1998017810A3 (en) 1998-10-15
WO1998017810A2 (en) 1998-04-30
CZ132399A3 (cs) 1999-12-15
RU2005105360A (ru) 2006-08-10
CZ295843B6 (cs) 2005-11-16

Similar Documents

Publication Publication Date Title
DE69724663D1 (de) Abstandshalter
DE59813814D1 (de) Haltevorrichtung
DE69734833D1 (de) Vitronektin rezeptor antagonisten
EP0986385A4 (de) Antagonisten des gonadorelins
DE69718508D1 (de) Antitraspirant zusammensetzung
ID23168A (id) Reseptor anatagonis vitronektin
DE59813852D1 (de) Haltevorrichtung
ID18359A (id) Komposisi mikrokapsul
DE59813815D1 (de) Haltevorrichtung
DE69827744D1 (de) Polybuten-1 enthaltende polyolefinzusammensetzung
NO991948L (no) Multifunksjonelle kimere hematopoetiske reseptoragonister
ID21009A (id) Komposisi untuk supositori
ID19589A (id) Komposisi
DK0906294T3 (da) Benzoxazinon-dopamin D4-receptor-antagonister
DE69506826D1 (de) 5-HT4 Rezeptoragonisten
NO985564L (no) Lysfiltrerende sammensetning
ID17561A (id) Komposisi untuk pemakaian luar
DE69825133D1 (de) Feste Brennstoffzusammensetzung
ID22707A (id) Komposisi pembersih
RU99111071A (ru) Многофункциональные химерные агонисты гемопоэтических рецепторов
DE59712835D1 (de) Stabilisierte monomerenzusammensetzung
BR9707835A (pt) Composiç
DE69735811D1 (de) Piperazinoderivate als neurokinin-antagonisten
BR9709815A (pt) Composicão
DE19782032T1 (de) Konzepthalter

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application