PT996462E - Preparados de combinacoes farmaceuticas contendo eritropoietina e hemoglobinas modificadas - Google Patents
Preparados de combinacoes farmaceuticas contendo eritropoietina e hemoglobinas modificadasInfo
- Publication number
- PT996462E PT996462E PT98930785T PT98930785T PT996462E PT 996462 E PT996462 E PT 996462E PT 98930785 T PT98930785 T PT 98930785T PT 98930785 T PT98930785 T PT 98930785T PT 996462 E PT996462 E PT 996462E
- Authority
- PT
- Portugal
- Prior art keywords
- preparations
- erythropoietin
- pharmaceutical combinations
- combinations containing
- containing erythropoietin
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 6
- 102000003951 Erythropoietin Human genes 0.000 title abstract 4
- 108090000394 Erythropoietin Proteins 0.000 title abstract 4
- 229940105423 erythropoietin Drugs 0.000 title abstract 4
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title abstract 4
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical class N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97110168A EP0885613A1 (de) | 1997-06-21 | 1997-06-21 | Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT996462E true PT996462E (pt) | 2004-12-31 |
Family
ID=8226937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98930785T PT996462E (pt) | 1997-06-21 | 1998-06-03 | Preparados de combinacoes farmaceuticas contendo eritropoietina e hemoglobinas modificadas |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US6440932B1 (enExample) |
| EP (2) | EP0885613A1 (enExample) |
| JP (3) | JP2002504913A (enExample) |
| KR (1) | KR100519904B1 (enExample) |
| CN (1) | CN1185010C (enExample) |
| AT (1) | ATE272405T1 (enExample) |
| AU (1) | AU743475B2 (enExample) |
| BR (1) | BR9810267A (enExample) |
| CA (1) | CA2294448C (enExample) |
| DE (1) | DE59811768D1 (enExample) |
| DK (1) | DK0996462T3 (enExample) |
| ES (1) | ES2226151T3 (enExample) |
| PT (1) | PT996462E (enExample) |
| TR (1) | TR199903192T2 (enExample) |
| WO (1) | WO1998058660A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ337465A (en) * | 1997-03-18 | 2002-04-26 | Roche Diagnostics Gmbh | Pharmaceutical containing erythropoietin and iron preparations for treating haemodialysis patients or anaemias |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| JP3967594B2 (ja) * | 2000-05-15 | 2007-08-29 | エフ．ホフマン−ラ ロシュ アーゲー | 新しい薬剤組成物 |
| CA2431964C (en) | 2000-12-20 | 2013-09-10 | F. Hoffmann-La Roche Ag | Conjugates of erythropoietin (pep) with polyethylene glycol (peg) |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| DE10215315A1 (de) * | 2002-04-05 | 2003-11-20 | Aventis Behring Gmbh Intellect | Human-Transferrin zur Behandlung der Anaemia of Chronic Disease (ACD) und des funktionellen Eisenmangels |
| US7459435B2 (en) * | 2002-08-29 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| US7459436B2 (en) * | 2002-11-22 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| JP2007517769A (ja) | 2003-09-29 | 2007-07-05 | ウォーレン ファーマシューティカルズ，インコーポレーテッド | 敗血症および癒着形成の治療および予防のための組織保護性サイトカイン |
| RU2273485C2 (ru) * | 2004-05-19 | 2006-04-10 | Виктор Николаевич Алейников | Железосодержащий препарат "феррал" |
| US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
| WO2008019214A1 (en) | 2006-08-04 | 2008-02-14 | Prolong Pharmaceuticals, Inc. | Modified erythropoietin |
| CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
| CL2008002054A1 (es) | 2007-07-17 | 2009-05-29 | Hoffmann La Roche | Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico. |
| EP3380487B1 (en) | 2015-11-23 | 2020-09-02 | Bristol-Myers Squibb Company | Additive systems for use in protein pegylation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin |
| US4826811A (en) * | 1986-06-20 | 1989-05-02 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
| JP2858752B2 (ja) * | 1987-04-10 | 1999-02-17 | オーソ・フアーマシユーチカル・コーポレーシヨン | 正常な哺乳動物のヘマトクリツト値の増大方法 |
| JPH03112934A (ja) * | 1989-09-27 | 1991-05-14 | Mitsubishi Kasei Corp | 圧縮成型可能な粉体組成物 |
| US5631219A (en) * | 1994-03-08 | 1997-05-20 | Somatogen, Inc. | Method of stimulating hematopoiesis with hemoglobin |
| CA2180529A1 (en) * | 1994-11-17 | 1996-05-30 | John Blue | Hemoglobin therapy in hemodialysis |
| DE19535571A1 (de) * | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
| DE69727241D1 (de) * | 1996-08-27 | 2004-02-19 | Hemosol Inc | Gesteigerte stimulation der erythropoesis |
-
1997
- 1997-06-21 EP EP97110168A patent/EP0885613A1/de not_active Withdrawn
-
1998
- 1998-06-03 DK DK98930785T patent/DK0996462T3/da active
- 1998-06-03 KR KR10-1999-7012111A patent/KR100519904B1/ko not_active Expired - Fee Related
- 1998-06-03 PT PT98930785T patent/PT996462E/pt unknown
- 1998-06-03 AU AU81098/98A patent/AU743475B2/en not_active Expired
- 1998-06-03 JP JP50365599A patent/JP2002504913A/ja not_active Withdrawn
- 1998-06-03 WO PCT/EP1998/003299 patent/WO1998058660A1/de not_active Ceased
- 1998-06-03 TR TR1999/03192T patent/TR199903192T2/xx unknown
- 1998-06-03 EP EP98930785A patent/EP0996462B1/de not_active Expired - Lifetime
- 1998-06-03 ES ES98930785T patent/ES2226151T3/es not_active Expired - Lifetime
- 1998-06-03 DE DE59811768T patent/DE59811768D1/de not_active Expired - Lifetime
- 1998-06-03 CA CA002294448A patent/CA2294448C/en not_active Expired - Lifetime
- 1998-06-03 BR BR9810267-2A patent/BR9810267A/pt not_active Application Discontinuation
- 1998-06-03 CN CNB988064324A patent/CN1185010C/zh not_active Expired - Lifetime
- 1998-06-03 US US09/446,378 patent/US6440932B1/en not_active Expired - Lifetime
- 1998-06-03 AT AT98930785T patent/ATE272405T1/de active
-
2002
- 2002-05-08 US US10/140,682 patent/US20020160956A1/en not_active Abandoned
-
2005
- 2005-03-28 US US11/091,876 patent/US20050197281A1/en not_active Abandoned
-
2007
- 2007-04-23 JP JP2007113275A patent/JP2007246530A/ja not_active Withdrawn
-
2011
- 2011-07-08 JP JP2011151443A patent/JP5785008B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BR9810267A (pt) | 2000-09-12 |
| KR20010014075A (ko) | 2001-02-26 |
| CN1185010C (zh) | 2005-01-19 |
| EP0885613A1 (de) | 1998-12-23 |
| CA2294448A1 (en) | 1998-12-30 |
| US20020160956A1 (en) | 2002-10-31 |
| JP2011246474A (ja) | 2011-12-08 |
| EP0996462B1 (de) | 2004-08-04 |
| US20050197281A1 (en) | 2005-09-08 |
| JP2002504913A (ja) | 2002-02-12 |
| KR100519904B1 (ko) | 2005-10-10 |
| ATE272405T1 (de) | 2004-08-15 |
| DK0996462T3 (da) | 2004-11-29 |
| AU8109898A (en) | 1999-01-04 |
| CN1261282A (zh) | 2000-07-26 |
| DE59811768D1 (de) | 2004-09-09 |
| TR199903192T2 (xx) | 2000-05-22 |
| US6440932B1 (en) | 2002-08-27 |
| AU743475B2 (en) | 2002-01-24 |
| JP5785008B2 (ja) | 2015-09-24 |
| WO1998058660A1 (de) | 1998-12-30 |
| CA2294448C (en) | 2007-12-11 |
| ES2226151T3 (es) | 2005-03-16 |
| EP0996462A1 (de) | 2000-05-03 |
| JP2007246530A (ja) | 2007-09-27 |
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