CN1185010C - 含有促红细胞生成素和修饰的血红蛋白的药物组合制品 - Google Patents

含有促红细胞生成素和修饰的血红蛋白的药物组合制品 Download PDF

Info

Publication number
CN1185010C
CN1185010C CNB988064324A CN98806432A CN1185010C CN 1185010 C CN1185010 C CN 1185010C CN B988064324 A CNB988064324 A CN B988064324A CN 98806432 A CN98806432 A CN 98806432A CN 1185010 C CN1185010 C CN 1185010C
Authority
CN
China
Prior art keywords
hemoglobin
erythropoietin
contain
epo
goods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB988064324A
Other languages
English (en)
Chinese (zh)
Other versions
CN1261282A (zh
Inventor
P·莱曼
M－H·汤
J·非尔斯坦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of CN1261282A publication Critical patent/CN1261282A/zh
Application granted granted Critical
Publication of CN1185010C publication Critical patent/CN1185010C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNB988064324A 1997-06-21 1998-06-03 含有促红细胞生成素和修饰的血红蛋白的药物组合制品 Expired - Lifetime CN1185010C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97110168.8 1997-06-21
EP97110168A EP0885613A1 (de) 1997-06-21 1997-06-21 Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin

Publications (2)

Publication Number Publication Date
CN1261282A CN1261282A (zh) 2000-07-26
CN1185010C true CN1185010C (zh) 2005-01-19

Family

ID=8226937

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988064324A Expired - Lifetime CN1185010C (zh) 1997-06-21 1998-06-03 含有促红细胞生成素和修饰的血红蛋白的药物组合制品

Country Status (15)

Country Link
US (3) US6440932B1 (enExample)
EP (2) EP0885613A1 (enExample)
JP (3) JP2002504913A (enExample)
KR (1) KR100519904B1 (enExample)
CN (1) CN1185010C (enExample)
AT (1) ATE272405T1 (enExample)
AU (1) AU743475B2 (enExample)
BR (1) BR9810267A (enExample)
CA (1) CA2294448C (enExample)
DE (1) DE59811768D1 (enExample)
DK (1) DK0996462T3 (enExample)
ES (1) ES2226151T3 (enExample)
PT (1) PT996462E (enExample)
TR (1) TR199903192T2 (enExample)
WO (1) WO1998058660A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998041226A1 (de) * 1997-03-18 1998-09-24 Roche Diagnostics Gmbh Pharmazeutische kombinationspräparate enthaltend erythropoietin und eisenpräparate
US7345019B1 (en) * 1999-04-13 2008-03-18 The Kenneth S. Warren Institute, Inc. Modulation of excitable tissue function by peripherally administered erythropoietin
MEP90708A (hr) * 2000-05-15 2011-12-20 Nova farmaceutska smješa
AU3323002A (en) 2000-12-20 2002-07-01 Hoffmann La Roche Erythropoietin conjugates
US20030072737A1 (en) 2000-12-29 2003-04-17 Michael Brines Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
US7767643B2 (en) 2000-12-29 2010-08-03 The Kenneth S. Warren Institute, Inc. Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs
DE10215315A1 (de) * 2002-04-05 2003-11-20 Aventis Behring Gmbh Intellect Human-Transferrin zur Behandlung der Anaemia of Chronic Disease (ACD) und des funktionellen Eisenmangels
US7459435B2 (en) * 2002-08-29 2008-12-02 Hoffmann-La Roche Inc. Treatment of disturbances of iron distribution
US7459436B2 (en) * 2002-11-22 2008-12-02 Hoffmann-La Roche Inc. Treatment of disturbances of iron distribution
CN1897959A (zh) 2003-09-29 2007-01-17 沃伦药品公司 用于治疗和预防脓毒病和粘连形成的组织保护细胞因子
RU2273485C2 (ru) * 2004-05-19 2006-04-10 Виктор Николаевич Алейников Железосодержащий препарат "феррал"
US7772182B2 (en) * 2004-08-05 2010-08-10 Alza Corporation Stable suspension formulations of erythropoietin receptor agonists
CN101534847A (zh) 2006-08-04 2009-09-16 普罗龙药品公司 修饰型促红细胞生成素
AR067537A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Purificacion de polipeptidos pegilados
CL2008002054A1 (es) * 2007-07-17 2009-05-29 Hoffmann La Roche Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico.
SMT202000649T1 (it) 2015-11-23 2021-01-05 Bristol Myers Squibb Co Sistemi di additivi per l'uso nella pegilazione di proteine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL77081A (en) 1984-12-04 1999-10-28 Genetics Inst Dna sequence encoding human erythropoietin process for the preparation thereof and a pharmaceutical composition of human erythropoietin
US4826811A (en) * 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
JP2858752B2 (ja) * 1987-04-10 1999-02-17 オーソ・フアーマシユーチカル・コーポレーシヨン 正常な哺乳動物のヘマトクリツト値の増大方法
JPH03112934A (ja) * 1989-09-27 1991-05-14 Mitsubishi Kasei Corp 圧縮成型可能な粉体組成物
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
JPH09507867A (ja) * 1994-11-17 1997-08-12 バクスター、インターナショナル、インコーポレイテッド 血液透析におけるヘモグロビン療法
DE19535571A1 (de) 1995-09-14 1997-03-20 Boehringer Mannheim Gmbh Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten
WO1998008537A1 (en) * 1996-08-27 1998-03-05 Hemosol Inc. Enhanced stimulation of erythropoiesis

Also Published As

Publication number Publication date
JP2007246530A (ja) 2007-09-27
BR9810267A (pt) 2000-09-12
DE59811768D1 (de) 2004-09-09
EP0996462B1 (de) 2004-08-04
KR20010014075A (ko) 2001-02-26
US6440932B1 (en) 2002-08-27
JP2002504913A (ja) 2002-02-12
KR100519904B1 (ko) 2005-10-10
ES2226151T3 (es) 2005-03-16
JP2011246474A (ja) 2011-12-08
US20050197281A1 (en) 2005-09-08
CA2294448A1 (en) 1998-12-30
AU743475B2 (en) 2002-01-24
TR199903192T2 (xx) 2000-05-22
EP0885613A1 (de) 1998-12-23
ATE272405T1 (de) 2004-08-15
DK0996462T3 (da) 2004-11-29
EP0996462A1 (de) 2000-05-03
PT996462E (pt) 2004-12-31
JP5785008B2 (ja) 2015-09-24
WO1998058660A1 (de) 1998-12-30
AU8109898A (en) 1999-01-04
CN1261282A (zh) 2000-07-26
CA2294448C (en) 2007-12-11
US20020160956A1 (en) 2002-10-31

Similar Documents

Publication Publication Date Title
JP5785008B2 (ja) エリトロポエチン及び修飾ヘモグロビンを含んでいる医薬配合製剤
CA2295140C (en) Stable insulin formulations
CA2297959C (en) Use of erythropoietin and iron preparations for the production of pharmaceutical combination preparations for the treatment of rheumatic diseases
US6333306B1 (en) Pharmaceutical combination preparations containing erythropoietin and iron preparations
BG65417B1 (bg) Приложение на еритропоетин или еритропоетинови производни за лечение на мозъчни исхемии
EP1283051B1 (en) Stable insulin formulations
RU2188033C2 (ru) Комбинированные фармацевтические препараты, содержащие эритропоэтин и препараты железа
HRP20020159A2 (en) Multi-dose erythropoietin formulations
Hudson et al. Darbepoetin alfa, a new therapy for the management of anemia of chronic kidney disease
JPH03190823A (ja) エリスロポエチン皮下又は筋肉投与剤
MXPA99011664A (en) Pharmaceutical combination preparations containing erythropoietin and modified haemoglobins
WO2010054446A1 (en) Combination of two or more peptides in a single stable lyophilized pharmaceutical compound
MXPA00001172A (en) The use of erythropoietin and iron preparations for producing pharmaceutical combination preparations for treating rheumatic diseases
KR20000076259A (ko) 에리트로포이에틴과 철 제제를 포함하는 약학 조합제제
MXPA99011446A (en) Stable insulin formulations

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term

Granted publication date: 20050119

CX01 Expiry of patent term