PT98708A - Processo para a preparacao de uma forma de dosagem de libertacao controlada biodegradavel, contendo um polimero poli(orto-ester) ou poliacetal - Google Patents
Processo para a preparacao de uma forma de dosagem de libertacao controlada biodegradavel, contendo um polimero poli(orto-ester) ou poliacetalInfo
- Publication number
- PT98708A PT98708A PT98708A PT9870891A PT98708A PT 98708 A PT98708 A PT 98708A PT 98708 A PT98708 A PT 98708A PT 9870891 A PT9870891 A PT 9870891A PT 98708 A PT98708 A PT 98708A
- Authority
- PT
- Portugal
- Prior art keywords
- biodegradavel
- orto
- liberation
- poly
- ester
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biological Depolymerization Polymers (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57074290A | 1990-08-22 | 1990-08-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT98708A true PT98708A (pt) | 1992-08-31 |
| PT98708B PT98708B (pt) | 1999-01-29 |
Family
ID=24280874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98708A PT98708B (pt) | 1990-08-22 | 1991-08-19 | Processo para a preparacao de uma forma de dosagem de libertacao controlada biodegradavel, contendo um polimero poli(orto-ester) ou poliacetal |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5837228A (pt) |
| EP (1) | EP0473223B1 (pt) |
| JP (1) | JP2588328B2 (pt) |
| AT (1) | ATE122230T1 (pt) |
| AU (1) | AU645594B2 (pt) |
| CA (1) | CA2049668C (pt) |
| DE (1) | DE69109581T2 (pt) |
| DK (1) | DK0473223T3 (pt) |
| ES (1) | ES2072530T3 (pt) |
| IE (1) | IE67141B1 (pt) |
| IL (1) | IL99180A (pt) |
| NZ (1) | NZ239370A (pt) |
| PT (1) | PT98708B (pt) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5211951A (en) * | 1991-07-24 | 1993-05-18 | Merck & Co., Inc. | Process for the manufacture of bioerodible poly (orthoester)s and polyacetals |
| ATE209907T1 (de) * | 1994-04-08 | 2001-12-15 | Atrix Lab Inc | Flüssige mittel zur wirkstoffabgabe |
| WO1999015166A1 (en) * | 1997-09-23 | 1999-04-01 | Pfizer Limited | Parasiticidal formulations |
| US6524602B1 (en) * | 1998-10-13 | 2003-02-25 | Craig G. Burkhart | Polymer delivery system in treatments for parasitic skin diseases |
| BR0008920A (pt) * | 1999-03-11 | 2001-12-18 | Nestle Sa | Cepas de lactobacillus capazes de prevenirdiarréia causada por bactéria patogênica erotaviroses |
| US20050042194A1 (en) | 2000-05-11 | 2005-02-24 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
| US6613355B2 (en) | 2000-05-11 | 2003-09-02 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
| ATE377048T1 (de) | 2000-09-06 | 2007-11-15 | Ap Pharma Inc | Abbaubare polyacetal-polymere |
| WO2002067895A2 (en) * | 2000-11-16 | 2002-09-06 | Durect Corporation | Implant dosage form and use thereof for the delivery of a cholesterol lowering agent |
| US6590059B2 (en) | 2001-05-11 | 2003-07-08 | Ap Pharma, Inc. | Bioerodible polyorthoesters from dioxolane-based diketene acetals |
| AUPR602401A0 (en) | 2001-06-29 | 2001-07-26 | Smart Drug Systems Inc | Sustained release delivery system |
| AUPR602501A0 (en) * | 2001-06-29 | 2001-07-26 | Smart Drug Systems Inc | Sustained release pharmaceutical composition |
| AUPR610501A0 (en) * | 2001-07-04 | 2001-07-26 | Smart Drug Systems Inc | Treatment of parasitic disease |
| US20050009762A1 (en) | 2003-06-06 | 2005-01-13 | Strobel Michael Albert | Application of water and organic solvent soluble ivermectin for topical and oral use |
| US6627613B2 (en) | 2001-07-23 | 2003-09-30 | Michael A. Strobel | Application of water and organic solvent soluble ivermectin for topical and oral use |
| US20040142902A1 (en) * | 2001-11-08 | 2004-07-22 | Struijker- Boudier Harry A.J. | Implant dosage form and use thereof for the delivery of a cholosterol lowering agent |
| US6524606B1 (en) | 2001-11-16 | 2003-02-25 | Ap Pharma, Inc. | Bioerodible polyorthoesters containing amine groups |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| US7288609B1 (en) * | 2003-03-04 | 2007-10-30 | Advanced Cardiovascular Systems, Inc. | Coatings for drug delivery devices based on poly (orthoesters) |
| WO2004100926A2 (en) * | 2003-05-13 | 2004-11-25 | Medtronic, Inc. | Delivery of agents using hydrolyzable leaving groups |
| CA2575988C (en) | 2004-08-04 | 2014-02-18 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| US20070264338A1 (en) * | 2006-05-12 | 2007-11-15 | Shah Devang T | Base-stabilized polyorthoester formulations |
| US20070264339A1 (en) * | 2006-05-12 | 2007-11-15 | Ap Pharma, Inc. | Base-stabilized polyorthoester formulations |
| US20070265329A1 (en) * | 2006-05-12 | 2007-11-15 | Devang Shah T | Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV) |
| WO2008005371A2 (en) | 2006-06-29 | 2008-01-10 | Medtronic, Inc. | Poly(orthoester) polymers, and methods of making and using same |
| ES2718612T3 (es) | 2007-12-20 | 2019-07-03 | Evonik Corp | Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual |
| US8956642B2 (en) | 2008-04-18 | 2015-02-17 | Medtronic, Inc. | Bupivacaine formulation in a polyorthoester carrier |
| US8475823B2 (en) | 2008-04-18 | 2013-07-02 | Medtronic, Inc. | Baclofen formulation in a polyorthoester carrier |
| AU2009324545A1 (en) * | 2008-12-11 | 2011-06-30 | A.P. Pharma, Inc. | Methods for enhancing stability of polyorthoesters and their formulations |
| WO2012013791A1 (en) | 2010-07-30 | 2012-02-02 | Ceva Sante Animale | Compositions for treating heartworm infestation |
| MX2013001039A (es) * | 2010-07-30 | 2013-06-03 | Ceva Sante Animale | Composiciones para controlar la infestacion por parasitos del corazon. |
| ES2659159T3 (es) | 2011-12-02 | 2018-03-14 | Merial, Inc. | Formulaciones de moxidectina inyectable de acción prolongada y nuevas formas cristalinas de moxidectina |
| KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4093709A (en) * | 1975-01-28 | 1978-06-06 | Alza Corporation | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) |
| US4150108A (en) * | 1975-12-29 | 1979-04-17 | Graham Neil B | Injectable medicinal compositions |
| JPS5441319A (en) * | 1977-06-28 | 1979-04-02 | Uni Sutorasukuraido Za | Pharmaceutical composition for treating tropic desease |
| US4356166A (en) * | 1978-12-08 | 1982-10-26 | University Of Utah | Time-release chemical delivery system |
| US4304767A (en) * | 1980-05-15 | 1981-12-08 | Sri International | Polymers of di- (and higher functionality) ketene acetals and polyols |
| US4636387A (en) * | 1982-06-21 | 1987-01-13 | Research Corporation | Anesthetic polyorganophosphazenes |
| US4639366A (en) * | 1984-06-06 | 1987-01-27 | Merck & Co., Inc. | Polymers containing pendant acid functionalities and labile backbone bonds |
| US4765973A (en) * | 1984-06-06 | 1988-08-23 | Merck & Co., Inc. | Polymers containing pendant acid functionalities and labile backbone bonds |
| US4764764A (en) * | 1984-11-27 | 1988-08-16 | Honeywell Inc. | Write-protect apparatus for bit mapped memory |
| CS254355B1 (en) * | 1985-04-10 | 1988-01-15 | Vladimir Saudek | Soluble and biodegradatable copolymeres activated for bond of biologicaly active substances |
| US4764364A (en) * | 1986-02-25 | 1988-08-16 | S R I International | Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product |
| AU2902289A (en) * | 1987-12-08 | 1989-07-05 | Mark Chasin | Method of forming bioerodible implants for improved controlled drug release |
-
1991
- 1991-08-13 NZ NZ239370A patent/NZ239370A/en unknown
- 1991-08-14 IL IL99180A patent/IL99180A/en not_active IP Right Cessation
- 1991-08-15 DE DE69109581T patent/DE69109581T2/de not_active Expired - Fee Related
- 1991-08-15 EP EP91202084A patent/EP0473223B1/en not_active Expired - Lifetime
- 1991-08-15 AT AT91202084T patent/ATE122230T1/de not_active IP Right Cessation
- 1991-08-15 DK DK91202084.9T patent/DK0473223T3/da active
- 1991-08-15 ES ES91202084T patent/ES2072530T3/es not_active Expired - Lifetime
- 1991-08-19 PT PT98708A patent/PT98708B/pt not_active IP Right Cessation
- 1991-08-21 JP JP3209024A patent/JP2588328B2/ja not_active Expired - Fee Related
- 1991-08-21 AU AU82678/91A patent/AU645594B2/en not_active Ceased
- 1991-08-21 IE IE296591A patent/IE67141B1/en not_active IP Right Cessation
- 1991-08-22 CA CA002049668A patent/CA2049668C/en not_active Expired - Fee Related
-
1992
- 1992-09-02 US US07/939,539 patent/US5837228A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE122230T1 (de) | 1995-05-15 |
| IE67141B1 (en) | 1996-03-06 |
| CA2049668C (en) | 2002-11-12 |
| IL99180A0 (en) | 1992-07-15 |
| IE912965A1 (en) | 1992-02-26 |
| DK0473223T3 (da) | 1995-07-10 |
| PT98708B (pt) | 1999-01-29 |
| DE69109581D1 (de) | 1995-06-14 |
| US5837228A (en) | 1998-11-17 |
| IL99180A (en) | 1998-01-04 |
| ES2072530T3 (es) | 1995-07-16 |
| JPH04230621A (ja) | 1992-08-19 |
| EP0473223B1 (en) | 1995-05-10 |
| JP2588328B2 (ja) | 1997-03-05 |
| AU645594B2 (en) | 1994-01-20 |
| CA2049668A1 (en) | 1992-02-23 |
| EP0473223A1 (en) | 1992-03-04 |
| NZ239370A (en) | 1994-04-27 |
| AU8267891A (en) | 1992-02-27 |
| DE69109581T2 (de) | 1996-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920402 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19981026 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000430 |