PT975594E - Processo para a producao de derivados de indole - Google Patents
Processo para a producao de derivados de indoleInfo
- Publication number
- PT975594E PT975594E PT98933651T PT98933651T PT975594E PT 975594 E PT975594 E PT 975594E PT 98933651 T PT98933651 T PT 98933651T PT 98933651 T PT98933651 T PT 98933651T PT 975594 E PT975594 E PT 975594E
- Authority
- PT
- Portugal
- Prior art keywords
- production
- indole derivatives
- indole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/04—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9714383.8A GB9714383D0 (en) | 1997-07-08 | 1997-07-08 | Improved process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT975594E true PT975594E (pt) | 2002-12-31 |
Family
ID=10815557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98933651T PT975594E (pt) | 1997-07-08 | 1998-06-16 | Processo para a producao de derivados de indole |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6281357B1 (pt) |
| EP (1) | EP0975594B1 (pt) |
| AR (1) | AR013183A1 (pt) |
| AT (1) | ATE224367T1 (pt) |
| AU (1) | AU8339798A (pt) |
| CA (1) | CA2286720A1 (pt) |
| DE (1) | DE69808068T2 (pt) |
| DK (1) | DK0975594T3 (pt) |
| ES (1) | ES2182342T3 (pt) |
| GB (1) | GB9714383D0 (pt) |
| IL (1) | IL132442A0 (pt) |
| PL (1) | PL337000A1 (pt) |
| PT (1) | PT975594E (pt) |
| WO (1) | WO1999002493A1 (pt) |
| ZA (1) | ZA985918B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9801690D0 (en) * | 1998-01-27 | 1998-03-25 | Pfizer Ltd | Therapeutic agents |
| US6100291A (en) * | 1998-03-16 | 2000-08-08 | Allelix Biopharmaceuticals Inc. | Pyrrolidine-indole compounds having 5-HT6 affinity |
| CN1729174B (zh) | 2002-12-20 | 2015-10-21 | 西巴特殊化学品控股有限公司 | 胺的合成以及用于合成胺的中间体 |
| US20100022581A1 (en) * | 2008-07-02 | 2010-01-28 | Memory Pharmaceuticals Corporation | Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity |
| CN102775342A (zh) * | 2011-05-12 | 2012-11-14 | 上海医药工业研究院 | 一种抗偏头痛药物阿莫曲坦的制备方法 |
| RS60209B1 (sr) | 2017-03-20 | 2020-06-30 | Forma Therapeutics Inc | Kompozicije pirolopirola kao aktivatori piruvat kinaze (pkr) |
| WO2020061255A1 (en) | 2018-09-19 | 2020-03-26 | Forma Therapeutics, Inc. | Activating pyruvate kinase r |
| US20220031671A1 (en) | 2018-09-19 | 2022-02-03 | Forma Therapeutics, Inc. | Treating sickle cell disease with a pyruvate kinase r activating compound |
| CN110483341A (zh) * | 2019-07-23 | 2019-11-22 | 上海药明康德新药开发有限公司 | 一种1-氰基-n-甲基甲磺酰胺的合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| HUT64326A (en) * | 1990-10-15 | 1993-12-28 | Pfizer | Process for production indole derivatives and pharmaceutical preparations containing these compounds |
| GB9103770D0 (en) * | 1991-02-22 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| CA2084531A1 (en) * | 1991-12-19 | 1993-06-20 | David W. Smith | Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines |
-
1997
- 1997-07-08 GB GBGB9714383.8A patent/GB9714383D0/en active Pending
-
1998
- 1998-06-16 PT PT98933651T patent/PT975594E/pt unknown
- 1998-06-16 DK DK98933651T patent/DK0975594T3/da active
- 1998-06-16 IL IL13244298A patent/IL132442A0/xx unknown
- 1998-06-16 WO PCT/EP1998/003996 patent/WO1999002493A1/en not_active Application Discontinuation
- 1998-06-16 AU AU83397/98A patent/AU8339798A/en not_active Abandoned
- 1998-06-16 PL PL98337000A patent/PL337000A1/xx unknown
- 1998-06-16 ES ES98933651T patent/ES2182342T3/es not_active Expired - Lifetime
- 1998-06-16 DE DE69808068T patent/DE69808068T2/de not_active Expired - Fee Related
- 1998-06-16 CA CA002286720A patent/CA2286720A1/en not_active Abandoned
- 1998-06-16 US US09/381,072 patent/US6281357B1/en not_active Expired - Fee Related
- 1998-06-16 AT AT98933651T patent/ATE224367T1/de not_active IP Right Cessation
- 1998-06-16 EP EP98933651A patent/EP0975594B1/en not_active Expired - Lifetime
- 1998-07-06 AR ARP980103279A patent/AR013183A1/es not_active Application Discontinuation
- 1998-07-06 ZA ZA9805918A patent/ZA985918B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999002493A1 (en) | 1999-01-21 |
| US6281357B1 (en) | 2001-08-28 |
| ZA985918B (en) | 2000-01-10 |
| DK0975594T3 (da) | 2002-10-14 |
| EP0975594A1 (en) | 2000-02-02 |
| GB9714383D0 (en) | 1997-09-10 |
| PL337000A1 (en) | 2000-07-31 |
| EP0975594B1 (en) | 2002-09-18 |
| AR013183A1 (es) | 2000-12-13 |
| IL132442A0 (en) | 2001-03-19 |
| ES2182342T3 (es) | 2003-03-01 |
| DE69808068D1 (de) | 2002-10-24 |
| CA2286720A1 (en) | 1999-01-21 |
| AU8339798A (en) | 1999-02-08 |
| ATE224367T1 (de) | 2002-10-15 |
| DE69808068T2 (de) | 2003-02-06 |
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