PT971710E - Utilizacao de queleritrina e radiacao para terapia de tumores - Google Patents
Utilizacao de queleritrina e radiacao para terapia de tumoresInfo
- Publication number
- PT971710E PT971710E PT98914302T PT98914302T PT971710E PT 971710 E PT971710 E PT 971710E PT 98914302 T PT98914302 T PT 98914302T PT 98914302 T PT98914302 T PT 98914302T PT 971710 E PT971710 E PT 971710E
- Authority
- PT
- Portugal
- Prior art keywords
- radiacao
- queleritrina
- tumor therapy
- chelerythrine
- irradiation
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- LLEJIEBFSOEYIV-UHFFFAOYSA-N chelerythrine Chemical compound C1=C2OCOC2=CC2=CC=C3C4=CC=C(OC)C(OC)=C4C=[N+](C)C3=C21 LLEJIEBFSOEYIV-UHFFFAOYSA-N 0.000 abstract 4
- RATMHCJTVBHJSU-UHFFFAOYSA-N Dihydrochelerythrine Natural products C1=C2OCOC2=CC2=C(N(C)C(O)C=3C4=CC=C(C=3OC)OC)C4=CC=C21 RATMHCJTVBHJSU-UHFFFAOYSA-N 0.000 abstract 2
- 230000006907 apoptotic process Effects 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/826,814 US6025365A (en) | 1997-03-25 | 1997-03-25 | Chelerythrine and radiation combined tumor therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT971710E true PT971710E (pt) | 2004-09-30 |
Family
ID=25247609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98914302T PT971710E (pt) | 1997-03-25 | 1998-03-25 | Utilizacao de queleritrina e radiacao para terapia de tumores |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6025365A (enExample) |
| EP (1) | EP0971710B1 (enExample) |
| JP (1) | JP2001521552A (enExample) |
| CN (1) | CN1172668C (enExample) |
| AT (1) | ATE267599T1 (enExample) |
| AU (1) | AU737613B2 (enExample) |
| CA (1) | CA2284992A1 (enExample) |
| DE (1) | DE69824165T2 (enExample) |
| DK (1) | DK0971710T3 (enExample) |
| ES (1) | ES2218814T3 (enExample) |
| PT (1) | PT971710E (enExample) |
| WO (1) | WO1998042339A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426351B1 (en) * | 2000-08-11 | 2002-07-30 | Dana-Farber Cancer, Inc. | Chelerythrine-based therapies for cancer |
| WO2003005965A2 (en) * | 2001-07-11 | 2003-01-23 | Musc Foundation For Research Development | Modulators of ceramidase and methods of use based thereon |
| US20030028097A1 (en) * | 2001-08-03 | 2003-02-06 | D'amico Anthony V. | Immobilizer probe system and method |
| WO2004016211A2 (en) * | 2002-08-08 | 2004-02-26 | Vanderbilt University | Pi3k antagonists as radiosensitizers |
| JP2004284961A (ja) * | 2003-03-19 | 2004-10-14 | Okinawa Pref Gov | 抗腫瘍成分をサルカケミカンから抽出した製剤、食品または食品添加物 |
| CN1292750C (zh) * | 2003-06-02 | 2007-01-03 | 张平 | 植物来源总生物碱组合物及其药物制剂 |
| MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| KR100822887B1 (ko) | 2006-10-12 | 2008-04-17 | 한국생명공학연구원 | 치매의 치료 또는 예방을 위한 조성물 |
| ITMI20080284A1 (it) * | 2008-02-22 | 2009-08-23 | Indena Spa | Agenti antitumorali a struttura benzofenantridinica e formulazioni che li contengono |
| CN101904849A (zh) * | 2010-08-19 | 2010-12-08 | 苏州大学 | 血根碱制备肿瘤放射治疗增敏药物的应用 |
| CN102552264A (zh) * | 2012-02-28 | 2012-07-11 | 苏州大学 | 血根碱在制备电离辐射防护剂中的应用 |
| CN116407537A (zh) * | 2023-03-03 | 2023-07-11 | 长春中医药大学 | 一种白屈菜红碱在制备用于治疗卵巢癌的药物中的用途 |
| CN118304300B (zh) * | 2024-04-12 | 2025-03-14 | 儋州市人民医院 | 一种具有麻醉作用的组合物及其在制备麻醉药物中的应用 |
| CN119548502A (zh) * | 2024-11-19 | 2025-03-04 | 中国药科大学 | 白屈菜红碱在制备黑色素瘤治疗药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US209331A (en) * | 1878-10-29 | Improvement in medical compounds | ||
| US433257A (en) * | 1890-07-29 | Salve | ||
| US2344830A (en) * | 1940-08-15 | 1944-03-21 | Wisconsin Alumni Res Found | Composition of matter for the chemical fixation of diseased tissue preparatory for surgical removal |
| US4145412A (en) * | 1977-02-14 | 1979-03-20 | Vipont Chemical Company | Composition for application to oral cavity and method for preparation thereof |
| US4406881A (en) * | 1980-05-20 | 1983-09-27 | Vipont Laboratories | Antimicrobial agent |
| US4376115A (en) * | 1980-08-05 | 1983-03-08 | Mccrorey Howard S | Method and composition for treating teeth and method for preparing same |
| US4599228A (en) * | 1981-01-19 | 1986-07-08 | Vipont Laboratories, Inc. | Antimicrobial agent |
| US5324520A (en) * | 1988-12-19 | 1994-06-28 | Vipont Pharmaceutical, Inc. | Intragingival delivery systems for treatment of periodontal disease |
| US5137912A (en) * | 1991-01-28 | 1992-08-11 | National Science Council Of Republic Of China | Chelerythrine inhibits platelet aggregation--a potential anti-aggregation drug |
| US5571797A (en) * | 1994-05-11 | 1996-11-05 | Arch Development Corporation | Method of inducing gene expression by ionizing radiation |
| AU6714396A (en) * | 1995-07-28 | 1997-02-26 | Trustees Of Boston University | Methods and compositions for treating cell proliferative disorders |
| HUP9601096A2 (hu) * | 1996-04-26 | 1998-01-28 | János Aradi | Anti-HIV-aktivitással rendelkező gyógynövényalapú gyógyászati és gyógyhatású készítmény,és vegyületek |
-
1997
- 1997-03-25 US US08/826,814 patent/US6025365A/en not_active Expired - Fee Related
-
1998
- 1998-03-25 WO PCT/US1998/005842 patent/WO1998042339A1/en not_active Ceased
- 1998-03-25 AT AT98914302T patent/ATE267599T1/de not_active IP Right Cessation
- 1998-03-25 EP EP98914302A patent/EP0971710B1/en not_active Expired - Lifetime
- 1998-03-25 JP JP54594798A patent/JP2001521552A/ja not_active Ceased
- 1998-03-25 PT PT98914302T patent/PT971710E/pt unknown
- 1998-03-25 CN CNB988048248A patent/CN1172668C/zh not_active Expired - Fee Related
- 1998-03-25 ES ES98914302T patent/ES2218814T3/es not_active Expired - Lifetime
- 1998-03-25 DE DE69824165T patent/DE69824165T2/de not_active Expired - Fee Related
- 1998-03-25 DK DK98914302T patent/DK0971710T3/da active
- 1998-03-25 AU AU68693/98A patent/AU737613B2/en not_active Ceased
- 1998-03-25 CA CA002284992A patent/CA2284992A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2284992A1 (en) | 1998-10-01 |
| CN1172668C (zh) | 2004-10-27 |
| CN1255061A (zh) | 2000-05-31 |
| ES2218814T3 (es) | 2004-11-16 |
| AU737613B2 (en) | 2001-08-23 |
| DK0971710T3 (da) | 2004-09-27 |
| ATE267599T1 (de) | 2004-06-15 |
| US6025365A (en) | 2000-02-15 |
| JP2001521552A (ja) | 2001-11-06 |
| WO1998042339A1 (en) | 1998-10-01 |
| DE69824165T2 (de) | 2005-06-09 |
| EP0971710A1 (en) | 2000-01-19 |
| DE69824165D1 (de) | 2004-07-01 |
| AU6869398A (en) | 1998-10-20 |
| EP0971710B1 (en) | 2004-05-26 |
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