DE69533873D1 - Krebstherapie mit lymphotoxin - Google Patents
Krebstherapie mit lymphotoxinInfo
- Publication number
- DE69533873D1 DE69533873D1 DE69533873T DE69533873T DE69533873D1 DE 69533873 D1 DE69533873 D1 DE 69533873D1 DE 69533873 T DE69533873 T DE 69533873T DE 69533873 T DE69533873 T DE 69533873T DE 69533873 D1 DE69533873 D1 DE 69533873D1
- Authority
- DE
- Germany
- Prior art keywords
- lymphotoxin
- cancer therapy
- cancer
- vivo
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US418314 | 1982-09-15 | ||
US26970494A | 1994-07-01 | 1994-07-01 | |
US269704 | 1994-07-01 | ||
US08/418,314 US5747023A (en) | 1994-07-01 | 1995-04-07 | Cancer therapy using lymphotoxin |
PCT/US1995/008085 WO1996001121A1 (en) | 1994-07-01 | 1995-06-26 | Cancer therapy using lymphotoxin |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69533873D1 true DE69533873D1 (de) | 2005-01-27 |
DE69533873T2 DE69533873T2 (de) | 2005-12-29 |
Family
ID=26953844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69533873T Expired - Lifetime DE69533873T2 (de) | 1994-07-01 | 1995-06-26 | Krebstherapie mit lymphotoxin |
Country Status (10)
Country | Link |
---|---|
US (1) | US5747023A (de) |
EP (1) | EP0768889B1 (de) |
JP (1) | JPH10502371A (de) |
AT (1) | ATE285247T1 (de) |
AU (1) | AU712197B2 (de) |
CA (1) | CA2191696A1 (de) |
DE (1) | DE69533873T2 (de) |
IL (1) | IL114382A (de) |
MX (1) | MX9606559A (de) |
WO (1) | WO1996001121A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6080407A (en) * | 1993-05-17 | 2000-06-27 | The Picower Institute For Medical Research | Diagnostic assays for MIF |
ZA964382B (en) * | 1995-06-06 | 1997-12-01 | Genentech Inc | Lymphotoxin and thrombopoietin for use in the treatment of cancer. |
US5925351A (en) | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
EP0832653A1 (de) | 1996-09-20 | 1998-04-01 | Max-Delbrück-Centrum Für Molekulare Medizin | Verwenddung von Cytokinen und cytotoxischen Substanzen in einem neuen Verfahren zur Tumorbehandlung |
US7060667B1 (en) | 1998-01-30 | 2006-06-13 | Biogen Idec Ma, Inc. | Treatment of follicular lymphomas using inhibitors of the LT pathway |
TR200002203T2 (tr) * | 1998-01-30 | 2000-12-21 | Biogen, Inc | Lemfotoksin (LT) sentezlenme yolunun inhibitörleri kullanılarak foliküler lemfomaların tedavisi. |
GB9808796D0 (en) * | 1998-04-24 | 1998-06-24 | Rowett Research Services Limit | Antithrombotic agents |
CL2007002926A1 (es) * | 2006-10-12 | 2008-05-16 | Genentech Inc | Anticuerpo antilinfotoxina alfa (lt-alfa); composicion con el anticuerpo; hibridoma pta-7538; acido nucleico codificante del anticuerpo; vector y celula huesped que comprenden el acido nucleico; metodo para inhibir la proliferacion celular activada p |
US8067375B2 (en) | 2006-10-20 | 2011-11-29 | Biogen Idec Ma Inc. | Treatment of demyelinating disorders with soluble lymphotoxin-β-receptor |
US8338376B2 (en) | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
WO2009062344A1 (fr) * | 2007-11-16 | 2009-05-22 | Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. | Utilisation de lymphotoxine pour sensibiliser des cellules tumorales à des médicaments chimiothérapeutiques |
AU2012320597C1 (en) | 2011-10-07 | 2015-10-15 | Baxalta GmbH | oxMIF as a diagnostic marker |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4405601A (en) * | 1981-05-21 | 1983-09-20 | Cancer Research Center | Extraction and purification of biologically active lymphokines |
US4920196A (en) * | 1982-07-30 | 1990-04-24 | Genentech, Inc. | Human lymphotoxin |
US4959457A (en) * | 1984-05-31 | 1990-09-25 | Genentech, Inc. | Anti-lymphotoxin |
IL75318A (en) * | 1984-05-31 | 1994-08-26 | Genentech Inc | Recombinant human memotoxin and methods for its recombinant production |
GR851626B (de) * | 1984-07-05 | 1985-11-26 | Genentech Inc | |
US4828830A (en) * | 1986-01-24 | 1989-05-09 | Genentech, Inc. | Method and composition for prophylaxis and treatment of viral infections |
DE3613167A1 (de) * | 1986-04-18 | 1987-10-29 | Basf Ag | Verwendung von tnf zur herstellung von arzneimitteln |
JPS63245692A (ja) * | 1987-04-01 | 1988-10-12 | Kanegafuchi Chem Ind Co Ltd | ヒト・リンホトキシンまたはその組成物 |
DE3837012A1 (de) * | 1988-01-15 | 1989-07-27 | Knoll Ag | Verwendung von tnf und lt zur herstellung von arzneimitteln |
AU3578189A (en) * | 1988-04-27 | 1989-11-24 | Immunomedics Inc. | Improved radiotherapy |
-
1995
- 1995-04-07 US US08/418,314 patent/US5747023A/en not_active Expired - Lifetime
- 1995-06-26 EP EP95924715A patent/EP0768889B1/de not_active Expired - Lifetime
- 1995-06-26 JP JP8503896A patent/JPH10502371A/ja not_active Ceased
- 1995-06-26 AT AT95924715T patent/ATE285247T1/de active
- 1995-06-26 MX MX9606559A patent/MX9606559A/es unknown
- 1995-06-26 WO PCT/US1995/008085 patent/WO1996001121A1/en active IP Right Grant
- 1995-06-26 AU AU29115/95A patent/AU712197B2/en not_active Expired
- 1995-06-26 CA CA002191696A patent/CA2191696A1/en not_active Abandoned
- 1995-06-26 DE DE69533873T patent/DE69533873T2/de not_active Expired - Lifetime
- 1995-06-28 IL IL11438295A patent/IL114382A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU712197B2 (en) | 1999-10-28 |
IL114382A0 (en) | 1995-10-31 |
US5747023A (en) | 1998-05-05 |
AU2911595A (en) | 1996-01-25 |
EP0768889A1 (de) | 1997-04-23 |
MX9606559A (es) | 1997-03-29 |
EP0768889B1 (de) | 2004-12-22 |
ATE285247T1 (de) | 2005-01-15 |
CA2191696A1 (en) | 1996-01-18 |
JPH10502371A (ja) | 1998-03-03 |
DE69533873T2 (de) | 2005-12-29 |
WO1996001121A1 (en) | 1996-01-18 |
IL114382A (en) | 2005-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |