PT93691A - Processo para a preparacao de metil-nucleosidos 3'-substituidos com accao antiviral - Google Patents

Processo para a preparacao de metil-nucleosidos 3'-substituidos com accao antiviral

Info

Publication number
PT93691A
PT93691A PT93691A PT9369190A PT93691A PT 93691 A PT93691 A PT 93691A PT 93691 A PT93691 A PT 93691A PT 9369190 A PT9369190 A PT 9369190A PT 93691 A PT93691 A PT 93691A
Authority
PT
Portugal
Prior art keywords
nucleosides
preparation
substituted methyl
antiviral action
antiviral
Prior art date
Application number
PT93691A
Other languages
English (en)
Other versions
PT93691B (pt
Inventor
John C Martin
Roman Z Sterzycki
Muzammil M Mansuri
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PT93691A publication Critical patent/PT93691A/pt
Publication of PT93691B publication Critical patent/PT93691B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT93691A 1989-04-06 1990-04-06 Processo para a preparacao de metil-nucleosidos 3'-substituidos com accao antiviral PT93691B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33403489A 1989-04-06 1989-04-06
US49245090A 1990-03-13 1990-03-13

Publications (2)

Publication Number Publication Date
PT93691A true PT93691A (pt) 1990-11-20
PT93691B PT93691B (pt) 1996-08-30

Family

ID=26989019

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93691A PT93691B (pt) 1989-04-06 1990-04-06 Processo para a preparacao de metil-nucleosidos 3'-substituidos com accao antiviral

Country Status (6)

Country Link
EP (1) EP0391411A3 (pt)
KR (1) KR930005991B1 (pt)
AU (1) AU633065B2 (pt)
CA (1) CA2013874A1 (pt)
FI (1) FI95384C (pt)
PT (1) PT93691B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164520A (en) * 1989-04-24 1992-11-17 E. R. Squibb & Sons, Inc. Intermediates for purinyl and pyrimidinyl tetrahydrofurans
US5145960A (en) * 1989-04-24 1992-09-08 E. R. Squibb & Sons, Inc. Pyrimidinyl tetrahydrofurans
US5059690A (en) * 1990-03-01 1991-10-22 E. R. Squibb & Sons, Inc. Purinyl tetrahydrofurans
US5272152A (en) * 1990-07-02 1993-12-21 E. R. Squibb & Sons, Inc. Purinyl and pyrimidinyl tetrahydrofurans
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
AU697612B2 (en) * 1994-05-31 1998-10-15 Medivir Ab Post exposure prevention of HIV
US5612319A (en) * 1994-05-31 1997-03-18 Medivir Ab Postexposure prevention of HIV infection or seroconversion
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
DE69812934T2 (de) * 1997-01-24 2004-01-29 Conpharma As Oslo Gemcitabin-derivate
WO2006070004A1 (en) 2004-12-30 2006-07-06 Medivir Ab Compounds useful in the treatment of hiv
CN102952104A (zh) * 2011-08-17 2013-03-06 黑龙江省松花江药业有限公司 一种呋喃类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211773A (en) * 1978-10-02 1980-07-08 Sloan Kettering Institute For Cancer Research 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
US4625020A (en) * 1983-11-18 1986-11-25 Bristol-Myers Company Nucleoside process
GB8708050D0 (en) * 1987-04-03 1987-05-07 Wellcome Found Therapeutic nucleosides
SE8701605D0 (sv) * 1987-04-16 1987-04-16 Astra Ab Novel medicinal compounds
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides
IL89258A0 (en) * 1988-02-16 1989-09-10 Lilly Co Eli 2',3'-dideoxy-2',2'-difluoro-nucleosides
GB8920534D0 (en) * 1989-09-11 1989-10-25 Wellcome Found Antiviral compounds

Also Published As

Publication number Publication date
AU633065B2 (en) 1993-01-21
EP0391411A3 (en) 1991-04-10
KR930005991B1 (ko) 1993-07-01
PT93691B (pt) 1996-08-30
FI95384C (fi) 1996-01-25
AU5256090A (en) 1990-10-11
FI95384B (fi) 1995-10-13
EP0391411A2 (en) 1990-10-10
KR900016249A (ko) 1990-11-13
FI901678A0 (fi) 1990-04-03
CA2013874A1 (en) 1990-10-06

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19960513

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19971130