PT916666E - 3-alquiloxi- ariloxi- ou arilalquiloxi-benzo¬b|tiofeno-2-carboxamidas como inibidores de adesao celular - Google Patents
3-alquiloxi- ariloxi- ou arilalquiloxi-benzo¬b|tiofeno-2-carboxamidas como inibidores de adesao celularInfo
- Publication number
- PT916666E PT916666E PT98123718T PT98123718T PT916666E PT 916666 E PT916666 E PT 916666E PT 98123718 T PT98123718 T PT 98123718T PT 98123718 T PT98123718 T PT 98123718T PT 916666 E PT916666 E PT 916666E
- Authority
- PT
- Portugal
- Prior art keywords
- carboxamides
- alkyloxy
- aryloxy
- arylalquiloxy
- benzob
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/840,361 US5208253A (en) | 1992-02-24 | 1992-02-24 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo(b) thiophene-2-carboxamides as inhibitors of cell adhesion |
| US08/015,005 US5356926A (en) | 1992-02-24 | 1993-02-09 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [β]thiophene-2-carboxamides as inhibitors of cell adhesion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT916666E true PT916666E (pt) | 2003-08-29 |
Family
ID=26686829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98123718T PT916666E (pt) | 1992-02-24 | 1993-02-23 | 3-alquiloxi- ariloxi- ou arilalquiloxi-benzo¬b|tiofeno-2-carboxamidas como inibidores de adesao celular |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5356926A (pt) |
| EP (2) | EP0916666B1 (pt) |
| JP (1) | JP3329460B2 (pt) |
| AT (2) | ATE239718T1 (pt) |
| AU (1) | AU665631B2 (pt) |
| CA (1) | CA2128701A1 (pt) |
| CZ (1) | CZ290968B6 (pt) |
| DE (2) | DE69332961T2 (pt) |
| DK (2) | DK0628038T3 (pt) |
| ES (2) | ES2137253T3 (pt) |
| FI (1) | FI943850A (pt) |
| GR (1) | GR3031095T3 (pt) |
| HU (1) | HUT68655A (pt) |
| NO (1) | NO307051B1 (pt) |
| NZ (1) | NZ249756A (pt) |
| PT (1) | PT916666E (pt) |
| RU (1) | RU2117665C1 (pt) |
| WO (1) | WO1993017008A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317076A1 (de) * | 1993-05-21 | 1994-11-24 | Bayer Ag | Benzthiophencarbonsäureamid-S-oxide |
| US5484808A (en) * | 1995-02-09 | 1996-01-16 | Eli Lilly And Company | Methods of inhibiting cell-cell adhesion |
| DE19642451A1 (de) * | 1996-10-15 | 1998-04-16 | Merck Patent Gmbh | Aminothiophencarbonsäureamide |
| CZ297324B6 (cs) * | 1996-12-13 | 2006-11-15 | Shionogi & Co., Ltd. | Benzothiofenkarboxamidové deriváty a antagonisty PGD2, které je obsahují |
| FR2777886B1 (fr) * | 1998-04-27 | 2002-05-31 | Adir | Nouveaux derives benzothiopheniques, benzofuraniques et indoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| WO2002012189A1 (fr) * | 2000-08-09 | 2002-02-14 | Mitsubishi Pharma Corporation | Composes amide bicycliques condenses et utilisations medicales associees |
| AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
| JP2005194192A (ja) * | 2002-01-11 | 2005-07-21 | Meiji Seika Kaisha Ltd | （４−オキソピペリジン−１−イル）安息香酸誘導体およびこれを用いたインテグリンαｖβ３阻害剤の製造法 |
| US7674822B2 (en) * | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
| WO2006101454A1 (en) * | 2005-03-21 | 2006-09-28 | S*Bio Pte Ltd | Benzothiophene derivatives: preparation and pharmaceutical applications |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703053A (en) * | 1985-10-28 | 1987-10-27 | Warner-Lambert Company | Benzothiophenes and benzofurans and antiallergic use thereof |
| US4761424A (en) * | 1985-10-01 | 1988-08-02 | Warner-Lambert Company | Enolamides, pharmaceutical compositions and methods for treating inflammation |
| US4800211A (en) * | 1986-08-18 | 1989-01-24 | Merck & Co., Inc. | 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors |
| DE3832848A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Benzothiophen-2-carboxamid-s,s-dioxide |
| DE3832846A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Verwendung von benzothiophen-2-carboxamid-s,s-dioxiden zur behandlung von krankheiten |
| WO1995005170A1 (en) * | 1993-08-13 | 1995-02-23 | Warner-Lambert Company | Methods of inhibiting hiv and inhibiting the activation of hiv |
-
1993
- 1993-02-09 US US08/015,005 patent/US5356926A/en not_active Expired - Fee Related
- 1993-02-23 EP EP98123718A patent/EP0916666B1/en not_active Expired - Lifetime
- 1993-02-23 CZ CZ19942017A patent/CZ290968B6/cs not_active IP Right Cessation
- 1993-02-23 AT AT98123718T patent/ATE239718T1/de not_active IP Right Cessation
- 1993-02-23 AU AU37331/93A patent/AU665631B2/en not_active Ceased
- 1993-02-23 DK DK93906217T patent/DK0628038T3/da active
- 1993-02-23 JP JP51506593A patent/JP3329460B2/ja not_active Expired - Fee Related
- 1993-02-23 DE DE69332961T patent/DE69332961T2/de not_active Expired - Fee Related
- 1993-02-23 ES ES93906217T patent/ES2137253T3/es not_active Expired - Lifetime
- 1993-02-23 RU RU94045150A patent/RU2117665C1/ru not_active IP Right Cessation
- 1993-02-23 CA CA002128701A patent/CA2128701A1/en not_active Abandoned
- 1993-02-23 PT PT98123718T patent/PT916666E/pt unknown
- 1993-02-23 EP EP93906217A patent/EP0628038B1/en not_active Expired - Lifetime
- 1993-02-23 AT AT93906217T patent/ATE182890T1/de not_active IP Right Cessation
- 1993-02-23 NZ NZ249756A patent/NZ249756A/en unknown
- 1993-02-23 DK DK98123718T patent/DK0916666T3/da active
- 1993-02-23 ES ES98123718T patent/ES2198639T3/es not_active Expired - Lifetime
- 1993-02-23 WO PCT/US1993/001672 patent/WO1993017008A1/en active IP Right Grant
- 1993-02-23 HU HU9402421A patent/HUT68655A/hu unknown
- 1993-02-23 DE DE69325899T patent/DE69325899T2/de not_active Expired - Fee Related
-
1994
- 1994-08-22 FI FI943850A patent/FI943850A/fi not_active IP Right Cessation
- 1994-08-24 NO NO943126A patent/NO307051B1/no not_active IP Right Cessation
-
1999
- 1999-08-26 GR GR990402178T patent/GR3031095T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5356926A (en) | 1994-10-18 |
| CZ290968B6 (cs) | 2002-11-13 |
| FI943850A (fi) | 1994-10-19 |
| JP3329460B2 (ja) | 2002-09-30 |
| RU94045150A (ru) | 1996-08-10 |
| DE69332961D1 (de) | 2003-06-12 |
| HU9402421D0 (en) | 1994-10-28 |
| DE69332961T2 (de) | 2004-03-11 |
| HUT68655A (en) | 1995-07-28 |
| DK0628038T3 (da) | 2000-02-28 |
| EP0628038A1 (en) | 1994-12-14 |
| EP0628038B1 (en) | 1999-08-04 |
| ES2137253T3 (es) | 1999-12-16 |
| DE69325899T2 (de) | 2000-02-24 |
| RU2117665C1 (ru) | 1998-08-20 |
| GR3031095T3 (en) | 1999-12-31 |
| CZ9402017A3 (en) | 1995-04-12 |
| DK0916666T3 (da) | 2003-09-01 |
| DE69325899D1 (de) | 1999-09-09 |
| AU665631B2 (en) | 1996-01-11 |
| WO1993017008A1 (en) | 1993-09-02 |
| NZ249756A (en) | 1996-05-28 |
| FI943850A0 (fi) | 1994-08-22 |
| JPH07504199A (ja) | 1995-05-11 |
| EP0916666A1 (en) | 1999-05-19 |
| EP0916666B1 (en) | 2003-05-07 |
| ATE182890T1 (de) | 1999-08-15 |
| ATE239718T1 (de) | 2003-05-15 |
| ES2198639T3 (es) | 2004-02-01 |
| NO943126D0 (no) | 1994-08-24 |
| AU3733193A (en) | 1993-09-13 |
| NO943126L (no) | 1994-08-24 |
| CA2128701A1 (en) | 1993-09-02 |
| NO307051B1 (no) | 2000-01-31 |
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