HUT68655A - 3-alkyloxy-, aryloxy- or arylalkyloxy-benzo [b] thiophene-2-carboxamides as inhibitors of cell adhesion - Google Patents
3-alkyloxy-, aryloxy- or arylalkyloxy-benzo [b] thiophene-2-carboxamides as inhibitors of cell adhesionInfo
- Publication number
- HUT68655A HUT68655A HU9402421A HU9402421A HUT68655A HU T68655 A HUT68655 A HU T68655A HU 9402421 A HU9402421 A HU 9402421A HU 9402421 A HU9402421 A HU 9402421A HU T68655 A HUT68655 A HU T68655A
- Authority
- HU
- Hungary
- Prior art keywords
- arylalkyloxy
- carboxamides
- alkyloxy
- aryloxy
- thiophene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/840,361 US5208253A (en) | 1992-02-24 | 1992-02-24 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo(b) thiophene-2-carboxamides as inhibitors of cell adhesion |
| US08/015,005 US5356926A (en) | 1992-02-24 | 1993-02-09 | 3-alkyloxy-, aryloxy-, or arylalkyloxy-benzo [β]thiophene-2-carboxamides as inhibitors of cell adhesion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9402421D0 HU9402421D0 (en) | 1994-10-28 |
| HUT68655A true HUT68655A (en) | 1995-07-28 |
Family
ID=26686829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9402421A HUT68655A (en) | 1992-02-24 | 1993-02-23 | 3-alkyloxy-, aryloxy- or arylalkyloxy-benzo [b] thiophene-2-carboxamides as inhibitors of cell adhesion |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5356926A (hu) |
| EP (2) | EP0628038B1 (hu) |
| JP (1) | JP3329460B2 (hu) |
| AT (2) | ATE182890T1 (hu) |
| AU (1) | AU665631B2 (hu) |
| CA (1) | CA2128701A1 (hu) |
| CZ (1) | CZ290968B6 (hu) |
| DE (2) | DE69332961T2 (hu) |
| DK (2) | DK0916666T3 (hu) |
| ES (2) | ES2198639T3 (hu) |
| FI (1) | FI943850A (hu) |
| GR (1) | GR3031095T3 (hu) |
| HU (1) | HUT68655A (hu) |
| NO (1) | NO307051B1 (hu) |
| NZ (1) | NZ249756A (hu) |
| PT (1) | PT916666E (hu) |
| RU (1) | RU2117665C1 (hu) |
| WO (1) | WO1993017008A1 (hu) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317076A1 (de) * | 1993-05-21 | 1994-11-24 | Bayer Ag | Benzthiophencarbonsäureamid-S-oxide |
| US5484808A (en) * | 1995-02-09 | 1996-01-16 | Eli Lilly And Company | Methods of inhibiting cell-cell adhesion |
| DE19642451A1 (de) * | 1996-10-15 | 1998-04-16 | Merck Patent Gmbh | Aminothiophencarbonsäureamide |
| DE69715448T2 (de) * | 1996-12-13 | 2003-08-07 | Shionogi & Co., Ltd. | Benzothiophenecarboxamid-derivate und diese enthaltende pgd2 antagonisten |
| FR2777886B1 (fr) * | 1998-04-27 | 2002-05-31 | Adir | Nouveaux derives benzothiopheniques, benzofuraniques et indoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| AU2001277731A1 (en) * | 2000-08-09 | 2002-02-18 | Welfide Corporation | Fused bicyclic amide compounds and medicinal use thereof |
| AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
| JP2005194192A (ja) * | 2002-01-11 | 2005-07-21 | Meiji Seika Kaisha Ltd | （４−オキソピペリジン−１−イル）安息香酸誘導体およびこれを用いたインテグリンαｖβ３阻害剤の製造法 |
| US7674822B2 (en) * | 2004-11-24 | 2010-03-09 | Wyeth | PTP1b inhibitors |
| WO2006101454A1 (en) * | 2005-03-21 | 2006-09-28 | S*Bio Pte Ltd | Benzothiophene derivatives: preparation and pharmaceutical applications |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703053A (en) * | 1985-10-28 | 1987-10-27 | Warner-Lambert Company | Benzothiophenes and benzofurans and antiallergic use thereof |
| US4761424A (en) * | 1985-10-01 | 1988-08-02 | Warner-Lambert Company | Enolamides, pharmaceutical compositions and methods for treating inflammation |
| US4800211A (en) * | 1986-08-18 | 1989-01-24 | Merck & Co., Inc. | 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors |
| DE3832848A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Benzothiophen-2-carboxamid-s,s-dioxide |
| DE3832846A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Verwendung von benzothiophen-2-carboxamid-s,s-dioxiden zur behandlung von krankheiten |
| WO1995005170A1 (en) * | 1993-08-13 | 1995-02-23 | Warner-Lambert Company | Methods of inhibiting hiv and inhibiting the activation of hiv |
-
1993
- 1993-02-09 US US08/015,005 patent/US5356926A/en not_active Expired - Fee Related
- 1993-02-23 CA CA002128701A patent/CA2128701A1/en not_active Abandoned
- 1993-02-23 DE DE69332961T patent/DE69332961T2/de not_active Expired - Fee Related
- 1993-02-23 DK DK98123718T patent/DK0916666T3/da active
- 1993-02-23 CZ CZ19942017A patent/CZ290968B6/cs not_active IP Right Cessation
- 1993-02-23 DE DE69325899T patent/DE69325899T2/de not_active Expired - Fee Related
- 1993-02-23 HU HU9402421A patent/HUT68655A/hu unknown
- 1993-02-23 AU AU37331/93A patent/AU665631B2/en not_active Ceased
- 1993-02-23 AT AT93906217T patent/ATE182890T1/de not_active IP Right Cessation
- 1993-02-23 NZ NZ249756A patent/NZ249756A/en unknown
- 1993-02-23 AT AT98123718T patent/ATE239718T1/de not_active IP Right Cessation
- 1993-02-23 DK DK93906217T patent/DK0628038T3/da active
- 1993-02-23 ES ES98123718T patent/ES2198639T3/es not_active Expired - Lifetime
- 1993-02-23 JP JP51506593A patent/JP3329460B2/ja not_active Expired - Fee Related
- 1993-02-23 EP EP93906217A patent/EP0628038B1/en not_active Expired - Lifetime
- 1993-02-23 EP EP98123718A patent/EP0916666B1/en not_active Expired - Lifetime
- 1993-02-23 PT PT98123718T patent/PT916666E/pt unknown
- 1993-02-23 WO PCT/US1993/001672 patent/WO1993017008A1/en active IP Right Grant
- 1993-02-23 ES ES93906217T patent/ES2137253T3/es not_active Expired - Lifetime
- 1993-02-23 RU RU94045150A patent/RU2117665C1/ru not_active IP Right Cessation
-
1994
- 1994-08-22 FI FI943850A patent/FI943850A/fi not_active IP Right Cessation
- 1994-08-24 NO NO943126A patent/NO307051B1/no not_active IP Right Cessation
-
1999
- 1999-08-26 GR GR990402178T patent/GR3031095T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69332961T2 (de) | 2004-03-11 |
| DK0916666T3 (da) | 2003-09-01 |
| PT916666E (pt) | 2003-08-29 |
| EP0916666A1 (en) | 1999-05-19 |
| ATE182890T1 (de) | 1999-08-15 |
| CA2128701A1 (en) | 1993-09-02 |
| DE69332961D1 (de) | 2003-06-12 |
| NO307051B1 (no) | 2000-01-31 |
| DK0628038T3 (da) | 2000-02-28 |
| EP0916666B1 (en) | 2003-05-07 |
| WO1993017008A1 (en) | 1993-09-02 |
| US5356926A (en) | 1994-10-18 |
| AU665631B2 (en) | 1996-01-11 |
| NO943126L (no) | 1994-08-24 |
| EP0628038A1 (en) | 1994-12-14 |
| DE69325899D1 (de) | 1999-09-09 |
| FI943850A (fi) | 1994-10-19 |
| RU94045150A (ru) | 1996-08-10 |
| FI943850A0 (fi) | 1994-08-22 |
| DE69325899T2 (de) | 2000-02-24 |
| ES2137253T3 (es) | 1999-12-16 |
| NZ249756A (en) | 1996-05-28 |
| NO943126D0 (no) | 1994-08-24 |
| CZ290968B6 (cs) | 2002-11-13 |
| EP0628038B1 (en) | 1999-08-04 |
| AU3733193A (en) | 1993-09-13 |
| GR3031095T3 (en) | 1999-12-31 |
| ES2198639T3 (es) | 2004-02-01 |
| JPH07504199A (ja) | 1995-05-11 |
| RU2117665C1 (ru) | 1998-08-20 |
| CZ9402017A3 (en) | 1995-04-12 |
| HU9402421D0 (en) | 1994-10-28 |
| JP3329460B2 (ja) | 2002-09-30 |
| ATE239718T1 (de) | 2003-05-15 |
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