PT900077E - Utilizacao de um metabolito de tomerifene para diminuir o nivel de colesterol no soro - Google Patents

Utilizacao de um metabolito de tomerifene para diminuir o nivel de colesterol no soro

Info

Publication number
PT900077E
PT900077E PT97906196T PT97906196T PT900077E PT 900077 E PT900077 E PT 900077E PT 97906196 T PT97906196 T PT 97906196T PT 97906196 T PT97906196 T PT 97906196T PT 900077 E PT900077 E PT 900077E
Authority
PT
Portugal
Prior art keywords
pct
tomerifene
metabolite
cholesterol
serum
Prior art date
Application number
PT97906196T
Other languages
English (en)
Inventor
Michael Degregorio
Pirkko Harkonen
Lauri Kangas
Tatu Miettinen
Eero Mantyla
Original Assignee
Orion Corp
Michael Degregorio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp, Michael Degregorio filed Critical Orion Corp
Publication of PT900077E publication Critical patent/PT900077E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
PT97906196T 1996-03-04 1997-03-04 Utilizacao de um metabolito de tomerifene para diminuir o nivel de colesterol no soro PT900077E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9604577.8A GB9604577D0 (en) 1996-03-04 1996-03-04 Serum cholesterol lowering agent

Publications (1)

Publication Number Publication Date
PT900077E true PT900077E (pt) 2002-07-31

Family

ID=10789817

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97906196T PT900077E (pt) 1996-03-04 1997-03-04 Utilizacao de um metabolito de tomerifene para diminuir o nivel de colesterol no soro

Country Status (13)

Country Link
US (1) US6037379A (pt)
EP (1) EP0900077B1 (pt)
JP (1) JP4113583B2 (pt)
AT (1) ATE212832T1 (pt)
AU (1) AU708336B2 (pt)
CA (1) CA2248032C (pt)
DE (1) DE69710326T2 (pt)
DK (1) DK0900077T3 (pt)
ES (1) ES2171889T3 (pt)
GB (1) GB9604577D0 (pt)
NZ (1) NZ331624A (pt)
PT (1) PT900077E (pt)
WO (1) WO1997032574A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9803521D0 (en) * 1998-02-19 1998-04-15 Orion Yhtymo Oy New compounds and pharmaceutical compositions thereof
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
SI1235776T1 (sl) * 1999-11-16 2006-06-30 Hormos Medical Corp Trifenilalkenski derivati in njihova uporaba kot selektivni estrogenski receptorski modulatorji
US6245819B1 (en) 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
US8124625B2 (en) 2001-09-14 2012-02-28 Shionogi & Co., Ltd. Method of enhancing the expression of apolipoprotein AI using olefin derivatives
US20040248989A1 (en) * 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
US8236861B2 (en) 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en) 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US8758821B2 (en) 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
DK2275098T3 (da) 2004-05-04 2012-08-20 Hormos Medical Ltd Hidtil ukendte orale formulationer af ospemifen
CN102702013B (zh) * 2005-11-28 2016-02-10 Gtx公司 核受体结合剂
AU2007252991B2 (en) 2006-05-22 2012-08-02 Hormos Medical Ltd. Selective estrogen receptor modulators or aromatase inhibitors for treating chronic nonbacterial prostatitis
WO2008099060A2 (en) 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene
ES2524002T3 (es) 2007-02-14 2014-12-03 Forendo Pharma Ltd. Método para la preparación de derivados de trifenilbuteno con valor terapéutico
EP2909163A1 (en) * 2012-10-19 2015-08-26 Fermion Oy A process for the preparation of ospemifene
JP6174156B2 (ja) 2012-10-19 2017-08-02 フェルミオン オサケ ユキチュア オスペミフェンの製造方法
WO2016108172A1 (en) 2014-12-29 2016-07-07 Olon S.P.A. Process for the preparation of ospemifene and fispemifene
US10138190B2 (en) * 2015-01-09 2018-11-27 Glenmark Pharmaceuticals Limited Process for preparation of ospemifene
CA2976811C (en) 2015-03-10 2023-06-27 Shionogi Inc. Solid dispersions of ospemifene
GR1009542B (el) 2018-04-25 2019-06-07 Φαρματεν Α.Β.Ε.Ε. Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126576B (en) * 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives

Also Published As

Publication number Publication date
CA2248032A1 (en) 1997-09-12
ATE212832T1 (de) 2002-02-15
CA2248032C (en) 2006-11-07
DK0900077T3 (da) 2002-03-25
NZ331624A (en) 2001-03-30
ES2171889T3 (es) 2002-09-16
WO1997032574A1 (en) 1997-09-12
DE69710326D1 (de) 2002-03-21
DE69710326T2 (de) 2002-08-22
US6037379A (en) 2000-03-14
AU708336B2 (en) 1999-08-05
AU2096897A (en) 1997-09-22
EP0900077A1 (en) 1999-03-10
JP4113583B2 (ja) 2008-07-09
EP0900077B1 (en) 2002-02-06
GB9604577D0 (en) 1996-05-01
JP2000506155A (ja) 2000-05-23

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