PT88874A - Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinante - Google Patents
Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinanteInfo
- Publication number
- PT88874A PT88874A PT88874A PT8887488A PT88874A PT 88874 A PT88874 A PT 88874A PT 88874 A PT88874 A PT 88874A PT 8887488 A PT8887488 A PT 8887488A PT 88874 A PT88874 A PT 88874A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- recombinant dna
- dna techniques
- human immunoglobulins
- immunoglobulins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11463287A | 1987-10-28 | 1987-10-28 | |
US25400488A | 1988-09-16 | 1988-09-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT88874A true PT88874A (pt) | 1989-07-31 |
PT88874B PT88874B (pt) | 1994-01-31 |
Family
ID=26812406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT88874A PT88874B (pt) | 1987-10-28 | 1988-10-27 | Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinante |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0314161A1 (pt) |
JP (1) | JPH02138989A (pt) |
AU (2) | AU634151B2 (pt) |
DK (1) | DK597288A (pt) |
FI (1) | FI884924A (pt) |
IL (1) | IL88175A0 (pt) |
MY (1) | MY104344A (pt) |
NO (1) | NO884795L (pt) |
NZ (1) | NZ226694A (pt) |
PT (1) | PT88874B (pt) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63267295A (ja) * | 1986-12-03 | 1988-11-04 | Sumitomo Chem Co Ltd | ヒト抗体、抗体遺伝子及び対応する組換え体 |
US5610034A (en) * | 1987-04-29 | 1997-03-11 | Alko Group Ltd. | Immunoglobulin production by trichoderma |
EP0493433B1 (en) * | 1989-09-19 | 1996-01-10 | Centocor, Inc. | Method for improving human monoclonal antibody production and cells used therein |
JPH04505709A (ja) * | 1989-11-07 | 1992-10-08 | ブリストル―マイアーズ スクイブ カンパニー | オリゴマー免疫グロブリン |
JPH05508768A (ja) * | 1990-07-16 | 1993-12-09 | オユ・アルコー・アーベー | トリコデルマによる免疫グロブリン製造 |
GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
ES2199216T3 (es) * | 1991-07-15 | 2004-02-16 | The Wellcome Foundation Limited | Produccion de anticuerpos. |
AU669124B2 (en) | 1991-09-18 | 1996-05-30 | Kyowa Hakko Kirin Co., Ltd. | Process for producing humanized chimera antibody |
AU669379B2 (en) * | 1992-09-07 | 1996-06-06 | Kyowa Hakko Kirin Co., Ltd. | Humanized antibodies |
US6042828A (en) | 1992-09-07 | 2000-03-28 | Kyowa Hakko Kogyo Co., Ltd. | Humanized antibodies to ganglioside GM2 |
US5939532A (en) * | 1993-09-07 | 1999-08-17 | Kyowa Hakko Kogyo Co., Ltd | Humanized antibodies to ganglioside GM2 |
US6130364A (en) | 1995-03-29 | 2000-10-10 | Abgenix, Inc. | Production of antibodies using Cre-mediated site-specific recombination |
CN101275136A (zh) | 2000-08-11 | 2008-10-01 | 麒麟医药株式会社 | 调节磷酸代谢,钙代谢,钙化和维生素d代谢的多肽及其编码dna |
EP2011802A3 (en) | 2001-04-27 | 2009-04-15 | Kyowa Hakko Kirin Co., Ltd. | Anti-CD40 monoclonal antibody |
ATE441666T1 (de) | 2001-12-28 | 2009-09-15 | Kyowa Hakko Kirin Co Ltd | Antikírper gegen den fibroblastenwachstumsfaktor 23 |
DK1523496T3 (da) | 2002-07-18 | 2011-10-17 | Merus B V | Rekombinant fremstilling af blanding af antistoffer |
USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
ES2408582T3 (es) | 2003-05-30 | 2013-06-21 | Merus B.V. | Biblioteca de Fab para la preparación de una mezcla de anticuerpos |
EP1707627B1 (en) | 2003-12-25 | 2012-11-14 | Kyowa Hakko Kirin Co., Ltd. | Antagonistic anti-CD40 antibody mutant |
WO2005068622A2 (en) | 2004-01-20 | 2005-07-28 | Merus B.V. | Mixtures of binding proteins |
US7579187B2 (en) | 2004-09-06 | 2009-08-25 | Kyoma Hakko Kirin Co., Ltd. | Anti-A33 antibody |
US8048421B2 (en) | 2006-03-23 | 2011-11-01 | Kyowa Hakko Kirin Co., Ltd. | Agonist antibody to human thrombopoietin receptor |
TWI390034B (zh) | 2006-04-06 | 2013-03-21 | Kyowa Hakko Kirin Co Ltd | Novel anti-CD98 antibody |
GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
US7947274B2 (en) | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
US7883705B2 (en) | 2007-02-14 | 2011-02-08 | Kyowa Hakko Kirin Co., Ltd. | Anti FGF23 antibody and a pharmaceutical composition comprising the same |
PE20141434A1 (es) | 2008-07-16 | 2014-10-22 | Inst Research In Biomedicine | Anticuerpos neutralizantes de citomegalovirus humano |
EP3594232A1 (en) | 2012-04-20 | 2020-01-15 | Merus N.V. | Methods and means for the production of ig-like molecules |
EP2869845B1 (en) | 2012-07-06 | 2019-08-28 | Genmab B.V. | Dimeric protein with triple mutations |
PL2711426T3 (pl) | 2012-09-24 | 2015-09-30 | Lonza Biologics Plc | Wektory ekspresyjne zawierające chimeryczne sekwencje promotora i wzmacniacza wirusa cytomegalii |
EP3470431A1 (en) | 2012-09-27 | 2019-04-17 | Merus N.V. | Bispecific igg antibodies as t cell engagers |
JP6771385B2 (ja) | 2014-02-28 | 2020-10-21 | メルス ナムローゼ フェンノートシャップ | 二重特異性抗体および医薬組成物 |
KR20240042540A (ko) | 2014-02-28 | 2024-04-02 | 메뤼스 엔.페. | ErbB-2와 ErbB-3에 결합하는 항체 |
RS57928B1 (sr) | 2015-07-10 | 2019-01-31 | Merus Nv | Antitela koja vezuju humani cd3 |
PL3365373T3 (pl) | 2015-10-23 | 2021-08-23 | Merus N.V. | Molekuły wiążące, które hamują wzrost nowotworu |
CN110650752A (zh) | 2017-03-31 | 2020-01-03 | 美勒斯公司 | 用于治疗具有NRG1融合基因的细胞的ErbB-2和ErbB3结合双特异性抗体 |
SG11202001050PA (en) | 2017-08-09 | 2020-03-30 | Merus Nv | Antibodies that bind egfr and cmet |
WO2019070047A1 (ja) | 2017-10-06 | 2019-04-11 | 小野薬品工業株式会社 | 二重特異性抗体 |
TWI804572B (zh) | 2018-02-09 | 2023-06-11 | 日商小野藥品工業股份有限公司 | 雙特異性抗體 |
TW202102544A (zh) | 2019-04-04 | 2021-01-16 | 日商小野藥品工業股份有限公司 | 雙特異性抗體 |
EP3998081A4 (en) | 2019-07-05 | 2023-07-12 | Ono Pharmaceutical Co., Ltd. | TREATMENT OF BLOOD CANCER WITH PD-1/CD3 DUAL SPECIFICITY PROTEIN |
WO2021020416A1 (ja) | 2019-07-30 | 2021-02-04 | 小野薬品工業株式会社 | 二重特異性抗体 |
US20220332825A1 (en) | 2019-08-08 | 2022-10-20 | Ono Pharmaceutical Co., Ltd. | Bispecific protein |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
DE3689123T2 (de) * | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
-
1988
- 1988-10-25 FI FI884924A patent/FI884924A/fi not_active IP Right Cessation
- 1988-10-25 NZ NZ226694A patent/NZ226694A/en unknown
- 1988-10-26 IL IL88175A patent/IL88175A0/xx unknown
- 1988-10-26 AU AU24363/88A patent/AU634151B2/en not_active Ceased
- 1988-10-27 NO NO88884795A patent/NO884795L/no unknown
- 1988-10-27 JP JP63271910A patent/JPH02138989A/ja active Pending
- 1988-10-27 DK DK597288A patent/DK597288A/da not_active Application Discontinuation
- 1988-10-27 MY MYPI88001221A patent/MY104344A/en unknown
- 1988-10-27 PT PT88874A patent/PT88874B/pt active IP Right Grant
- 1988-10-28 EP EP88117998A patent/EP0314161A1/en not_active Ceased
-
1992
- 1992-10-01 AU AU26082/92A patent/AU2608292A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU634151B2 (en) | 1993-02-18 |
IL88175A0 (en) | 1989-06-30 |
NO884795L (no) | 1989-04-28 |
JPH02138989A (ja) | 1990-05-28 |
FI884924A0 (fi) | 1988-10-25 |
NZ226694A (en) | 1994-04-27 |
DK597288A (da) | 1989-04-29 |
MY104344A (en) | 1994-03-31 |
NO884795D0 (no) | 1988-10-27 |
EP0314161A1 (en) | 1989-05-03 |
DK597288D0 (da) | 1988-10-27 |
AU2436388A (en) | 1989-06-01 |
AU2608292A (en) | 1992-12-17 |
PT88874B (pt) | 1994-01-31 |
FI884924A (fi) | 1989-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19930709 |