PT88874A - Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinante - Google Patents

Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinante

Info

Publication number
PT88874A
PT88874A PT88874A PT8887488A PT88874A PT 88874 A PT88874 A PT 88874A PT 88874 A PT88874 A PT 88874A PT 8887488 A PT8887488 A PT 8887488A PT 88874 A PT88874 A PT 88874A
Authority
PT
Portugal
Prior art keywords
preparation
recombinant dna
dna techniques
human immunoglobulins
immunoglobulins
Prior art date
Application number
PT88874A
Other languages
English (en)
Other versions
PT88874B (pt
Inventor
Linda J Harris
Leah A Lipsich
Michael A Walls
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of PT88874A publication Critical patent/PT88874A/pt
Publication of PT88874B publication Critical patent/PT88874B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT88874A 1987-10-28 1988-10-27 Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinante PT88874B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11463287A 1987-10-28 1987-10-28
US25400488A 1988-09-16 1988-09-16

Publications (2)

Publication Number Publication Date
PT88874A true PT88874A (pt) 1989-07-31
PT88874B PT88874B (pt) 1994-01-31

Family

ID=26812406

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88874A PT88874B (pt) 1987-10-28 1988-10-27 Processo para a preparacao de imunoglobulinas humanas por tecnicas de dna recombinante

Country Status (10)

Country Link
EP (1) EP0314161A1 (pt)
JP (1) JPH02138989A (pt)
AU (2) AU634151B2 (pt)
DK (1) DK597288A (pt)
FI (1) FI884924A (pt)
IL (1) IL88175A0 (pt)
MY (1) MY104344A (pt)
NO (1) NO884795L (pt)
NZ (1) NZ226694A (pt)
PT (1) PT88874B (pt)

Families Citing this family (44)

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Publication number Priority date Publication date Assignee Title
JPS63267295A (ja) * 1986-12-03 1988-11-04 Sumitomo Chem Co Ltd ヒト抗体、抗体遺伝子及び対応する組換え体
US5610034A (en) * 1987-04-29 1997-03-11 Alko Group Ltd. Immunoglobulin production by trichoderma
EP0493433B1 (en) * 1989-09-19 1996-01-10 Centocor, Inc. Method for improving human monoclonal antibody production and cells used therein
JPH04505709A (ja) * 1989-11-07 1992-10-08 ブリストル―マイアーズ　スクイブ　カンパニー オリゴマー免疫グロブリン
JPH05508768A (ja) * 1990-07-16 1993-12-09 オユ・アルコー・アーベー トリコデルマによる免疫グロブリン製造
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
ES2199216T3 (es) * 1991-07-15 2004-02-16 The Wellcome Foundation Limited Produccion de anticuerpos.
AU669124B2 (en) 1991-09-18 1996-05-30 Kyowa Hakko Kirin Co., Ltd. Process for producing humanized chimera antibody
AU669379B2 (en) * 1992-09-07 1996-06-06 Kyowa Hakko Kirin Co., Ltd. Humanized antibodies
US6042828A (en) 1992-09-07 2000-03-28 Kyowa Hakko Kogyo Co., Ltd. Humanized antibodies to ganglioside GM2
US5939532A (en) * 1993-09-07 1999-08-17 Kyowa Hakko Kogyo Co., Ltd Humanized antibodies to ganglioside GM2
US6130364A (en) 1995-03-29 2000-10-10 Abgenix, Inc. Production of antibodies using Cre-mediated site-specific recombination
CN101275136A (zh) 2000-08-11 2008-10-01 麒麟医药株式会社 调节磷酸代谢,钙代谢,钙化和维生素d代谢的多肽及其编码dna
EP2011802A3 (en) 2001-04-27 2009-04-15 Kyowa Hakko Kirin Co., Ltd. Anti-CD40 monoclonal antibody
ATE441666T1 (de) 2001-12-28 2009-09-15 Kyowa Hakko Kirin Co Ltd Antikírper gegen den fibroblastenwachstumsfaktor 23
DK1523496T3 (da) 2002-07-18 2011-10-17 Merus B V Rekombinant fremstilling af blanding af antistoffer
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
ES2408582T3 (es) 2003-05-30 2013-06-21 Merus B.V. Biblioteca de Fab para la preparación de una mezcla de anticuerpos
EP1707627B1 (en) 2003-12-25 2012-11-14 Kyowa Hakko Kirin Co., Ltd. Antagonistic anti-CD40 antibody mutant
WO2005068622A2 (en) 2004-01-20 2005-07-28 Merus B.V. Mixtures of binding proteins
US7579187B2 (en) 2004-09-06 2009-08-25 Kyoma Hakko Kirin Co., Ltd. Anti-A33 antibody
US8048421B2 (en) 2006-03-23 2011-11-01 Kyowa Hakko Kirin Co., Ltd. Agonist antibody to human thrombopoietin receptor
TWI390034B (zh) 2006-04-06 2013-03-21 Kyowa Hakko Kirin Co Ltd Novel anti-CD98 antibody
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
US7883705B2 (en) 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
PE20141434A1 (es) 2008-07-16 2014-10-22 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano
EP3594232A1 (en) 2012-04-20 2020-01-15 Merus N.V. Methods and means for the production of ig-like molecules
EP2869845B1 (en) 2012-07-06 2019-08-28 Genmab B.V. Dimeric protein with triple mutations
PL2711426T3 (pl) 2012-09-24 2015-09-30 Lonza Biologics Plc Wektory ekspresyjne zawierające chimeryczne sekwencje promotora i wzmacniacza wirusa cytomegalii
EP3470431A1 (en) 2012-09-27 2019-04-17 Merus N.V. Bispecific igg antibodies as t cell engagers
JP6771385B2 (ja) 2014-02-28 2020-10-21 メルス ナムローゼ フェンノートシャップ 二重特異性抗体および医薬組成物
KR20240042540A (ko) 2014-02-28 2024-04-02 메뤼스 엔.페. ErbB-2와 ErbB-3에 결합하는 항체
RS57928B1 (sr) 2015-07-10 2019-01-31 Merus Nv Antitela koja vezuju humani cd3
PL3365373T3 (pl) 2015-10-23 2021-08-23 Merus N.V. Molekuły wiążące, które hamują wzrost nowotworu
CN110650752A (zh) 2017-03-31 2020-01-03 美勒斯公司 用于治疗具有NRG1融合基因的细胞的ErbB-2和ErbB3结合双特异性抗体
SG11202001050PA (en) 2017-08-09 2020-03-30 Merus Nv Antibodies that bind egfr and cmet
WO2019070047A1 (ja) 2017-10-06 2019-04-11 小野薬品工業株式会社 二重特異性抗体
TWI804572B (zh) 2018-02-09 2023-06-11 日商小野藥品工業股份有限公司 雙特異性抗體
TW202102544A (zh) 2019-04-04 2021-01-16 日商小野藥品工業股份有限公司 雙特異性抗體
EP3998081A4 (en) 2019-07-05 2023-07-12 Ono Pharmaceutical Co., Ltd. TREATMENT OF BLOOD CANCER WITH PD-1/CD3 DUAL SPECIFICITY PROTEIN
WO2021020416A1 (ja) 2019-07-30 2021-02-04 小野薬品工業株式会社 二重特異性抗体
US20220332825A1 (en) 2019-08-08 2022-10-20 Ono Pharmaceutical Co., Ltd. Bispecific protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3689123T2 (de) * 1985-11-01 1994-03-03 Xoma Corp Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung.

Also Published As

Publication number Publication date
AU634151B2 (en) 1993-02-18
IL88175A0 (en) 1989-06-30
NO884795L (no) 1989-04-28
JPH02138989A (ja) 1990-05-28
FI884924A0 (fi) 1988-10-25
NZ226694A (en) 1994-04-27
DK597288A (da) 1989-04-29
MY104344A (en) 1994-03-31
NO884795D0 (no) 1988-10-27
EP0314161A1 (en) 1989-05-03
DK597288D0 (da) 1988-10-27
AU2436388A (en) 1989-06-01
AU2608292A (en) 1992-12-17
PT88874B (pt) 1994-01-31
FI884924A (fi) 1989-04-29

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930709