FI884924A0 - Humanimmuglobulin som producerats med hybrid-dna-teknik. - Google Patents

Humanimmuglobulin som producerats med hybrid-dna-teknik.

Info

Publication number
FI884924A0
FI884924A0 FI884924A FI884924A FI884924A0 FI 884924 A0 FI884924 A0 FI 884924A0 FI 884924 A FI884924 A FI 884924A FI 884924 A FI884924 A FI 884924A FI 884924 A0 FI884924 A0 FI 884924A0
Authority
FI
Finland
Prior art keywords
producerats
humanimmuglobulin
teknik
som
med
Prior art date
Application number
FI884924A
Other languages
English (en)
Other versions
FI884924A (fi
Inventor
Linda J Harris
Leah A Lipsich
Michael A Walls
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of FI884924A0 publication Critical patent/FI884924A0/fi
Publication of FI884924A publication Critical patent/FI884924A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI884924A 1987-10-28 1988-10-25 Humanimmuglobulin som producerats med hybrid-dna-teknik. FI884924A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11463287A 1987-10-28 1987-10-28
US25400488A 1988-09-16 1988-09-16

Publications (2)

Publication Number Publication Date
FI884924A0 true FI884924A0 (fi) 1988-10-25
FI884924A FI884924A (fi) 1989-04-29

Family

ID=26812406

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884924A FI884924A (fi) 1987-10-28 1988-10-25 Humanimmuglobulin som producerats med hybrid-dna-teknik.

Country Status (10)

Country Link
EP (1) EP0314161A1 (fi)
JP (1) JPH02138989A (fi)
AU (2) AU634151B2 (fi)
DK (1) DK597288A (fi)
FI (1) FI884924A (fi)
IL (1) IL88175A0 (fi)
MY (1) MY104344A (fi)
NO (1) NO884795L (fi)
NZ (1) NZ226694A (fi)
PT (1) PT88874B (fi)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63267295A (ja) * 1986-12-03 1988-11-04 Sumitomo Chem Co Ltd ヒト抗体、抗体遺伝子及び対応する組換え体
US5610034A (en) * 1987-04-29 1997-03-11 Alko Group Ltd. Immunoglobulin production by trichoderma
ATE132907T1 (de) * 1989-09-19 1996-01-15 Centocor Inc Verfahren zur verbesserten herstellung von menschlichen antikörpern sowie hierzu benutzte zellen
EP0462246A4 (en) * 1989-11-07 1992-11-25 Bristol-Myers Squibb Company Oligomeric immunoglobulins
AU657911B2 (en) * 1990-07-16 1995-03-30 Roal Oy Immunoglobulin production by (Trichoderma)
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
IE922287A1 (en) * 1991-07-15 1993-01-27 Wellcome Found Production of antibodies
CA2078539C (en) 1991-09-18 2005-08-02 Kenya Shitara Process for producing humanized chimera antibody
US5830470A (en) * 1992-09-07 1998-11-03 Kyowa Hakko Kogyo Co., Ltd. Humanized antibodies to ganglioside GM2
US5939532A (en) * 1993-09-07 1999-08-17 Kyowa Hakko Kogyo Co., Ltd Humanized antibodies to ganglioside GM2
US6042828A (en) 1992-09-07 2000-03-28 Kyowa Hakko Kogyo Co., Ltd. Humanized antibodies to ganglioside GM2
US6130364A (en) * 1995-03-29 2000-10-10 Abgenix, Inc. Production of antibodies using Cre-mediated site-specific recombination
EP1310554B1 (en) 2000-08-11 2010-05-26 Kyowa Hakko Kirin Co., Ltd. Polypeptides controlling phosphoric acid metabolism, calcium metabolism, calcification and vitamin d metabolism and dnas encoding the same
CN101508734A (zh) 2001-04-27 2009-08-19 协和发酵麒麟株式会社 抗cd40单克隆抗体
CN100519584C (zh) 2001-12-28 2009-07-29 麒麟医药株式会社 抗成纤维细胞生长因子23的抗体
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
CN101537180B (zh) 2002-07-18 2016-02-10 莫鲁斯有限公司 抗体混合物的重组生产
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
ES2408582T3 (es) 2003-05-30 2013-06-21 Merus B.V. Biblioteca de Fab para la preparación de una mezcla de anticuerpos
PT1707627E (pt) 2003-12-25 2013-01-24 Kyowa Hakko Kirin Co Ltd Mutante antagonista de anticorpo anti-cd40
DK1737971T3 (da) 2004-01-20 2017-11-13 Merus Nv Blandinger af bindingsproteiner
EP2145954A1 (en) 2004-09-06 2010-01-20 Kyowa Hakko Kirin Co., Ltd. Anti-A33 antibody
EP2006380A4 (en) 2006-03-23 2010-08-11 Kyowa Hakko Kirin Co Ltd AGONIST ANTIBODY AGAINST THE HUMAN THROMBOPOIETINE RECEPTOR
TWI390034B (zh) 2006-04-06 2013-03-21 Kyowa Hakko Kirin Co Ltd Novel anti-CD98 antibody
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
US7883705B2 (en) 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
MX2011000543A (es) 2008-07-16 2011-04-27 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano y uso de los mismos.
PT2838918T (pt) 2012-04-20 2019-08-23 Merus Nv Métodos e meios para a produção de moléculas heterrodiméricas do tipo ig
BR112015000167B1 (pt) 2012-07-06 2021-11-23 Genmab B.V. Proteína dimérica, proteína, composição, kit de partes e seus usos, bem como método para aumentar a oligomerização em solução de uma proteína dimérica compreendendo um primeiro e segundo polipeptídeo, cada um compreendendo pelo menos as regiões ch2 e ch3 de uma cadeia pesada de igg1 humana e proteína dimérica variante
EP2711426B1 (en) * 2012-09-24 2015-04-08 Lonza Biologics plc Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences
SI2900694T1 (sl) 2012-09-27 2018-12-31 Merus N.V. Bispecifična IGG protitelesa kot vključitelji T-celic
CA2941030A1 (en) 2014-02-28 2015-09-03 Merus N.V. Antibodies that bind egfr and erbb3
CN106459212B (zh) 2014-02-28 2021-07-13 美勒斯公司 结合erbb-2和erbb-3的抗体
ES2812303T3 (es) 2015-07-10 2021-03-16 Merus Nv Anticuerpo que se une a CD3 humano
HUE055222T2 (hu) 2015-10-23 2021-11-29 Merus Nv Megkötõ molekulák, amelyek gátolják a rák növekedését
MX2019011660A (es) 2017-03-31 2019-11-18 Merus Nv Anticuerpos biespecificos que se unen al receptor 2 del factor de crecimiento humano (erbb-2) y receptor 3 del factor de crecimiento humano (erbb3) para usarse en el tratamiento de celulas que tienen un gen de fusion de neuregulina-1 (nrg1).
CN111094351A (zh) 2017-08-09 2020-05-01 美勒斯公司 结合EGFR和cMET的抗体
WO2019070047A1 (ja) 2017-10-06 2019-04-11 小野薬品工業株式会社 二重特異性抗体
TWI804572B (zh) 2018-02-09 2023-06-11 日商小野藥品工業股份有限公司 雙特異性抗體
TW202102544A (zh) 2019-04-04 2021-01-16 日商小野藥品工業股份有限公司 雙特異性抗體
WO2021006199A1 (ja) 2019-07-05 2021-01-14 小野薬品工業株式会社 Ｐｄ－１／ｃｄ３二重特異性タンパク質による血液がん治療
TW202118790A (zh) 2019-07-30 2021-05-16 日商小野藥品工業股份有限公司 雙特異性抗體
JPWO2021025140A1 (fi) 2019-08-08 2021-02-11

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3689123T2 (de) * 1985-11-01 1994-03-03 Xoma Corp Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung.

Also Published As

Publication number Publication date
MY104344A (en) 1994-03-31
FI884924A (fi) 1989-04-29
AU2608292A (en) 1992-12-17
PT88874B (pt) 1994-01-31
AU2436388A (en) 1989-06-01
AU634151B2 (en) 1993-02-18
NZ226694A (en) 1994-04-27
NO884795D0 (no) 1988-10-27
DK597288A (da) 1989-04-29
DK597288D0 (da) 1988-10-27
EP0314161A1 (en) 1989-05-03
JPH02138989A (ja) 1990-05-28
NO884795L (no) 1989-04-28
PT88874A (pt) 1989-07-31
IL88175A0 (en) 1989-06-30

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Legal Events

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FD Application lapsed
MM Patent lapsed

Owner name: ONCOGEN