PT88269A - Processo para evitar a formacao de um hidrato cristalino numa dispersao de um liquido numa matriz nao aquosa - Google Patents

Processo para evitar a formacao de um hidrato cristalino numa dispersao de um liquido numa matriz nao aquosa

Info

Publication number
PT88269A
PT88269A PT88269A PT8826988A PT88269A PT 88269 A PT88269 A PT 88269A PT 88269 A PT88269 A PT 88269A PT 8826988 A PT8826988 A PT 8826988A PT 88269 A PT88269 A PT 88269A
Authority
PT
Portugal
Prior art keywords
subunits
dispersion
liquid
crystalline
dispersions
Prior art date
Application number
PT88269A
Other languages
English (en)
Other versions
PT88269B (pt
Inventor
Robert M Gale
David James Enscore
Patricia S Campbell
Arnold Kaufman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22189156&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT88269(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of PT88269A publication Critical patent/PT88269A/pt
Publication of PT88269B publication Critical patent/PT88269B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Laminated Bodies (AREA)
  • Liquid Crystal Substances (AREA)
  • Colloid Chemistry (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
PT88269A 1987-08-13 1988-08-12 Processo para evitar a formacao de um hidrato cristalino numa dispersao de um liquido numa matriz nao aquosa PT88269B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/085,052 US4832953A (en) 1987-08-13 1987-08-13 Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix

Publications (2)

Publication Number Publication Date
PT88269A true PT88269A (pt) 1989-06-30
PT88269B PT88269B (pt) 1996-01-31

Family

ID=22189156

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88269A PT88269B (pt) 1987-08-13 1988-08-12 Processo para evitar a formacao de um hidrato cristalino numa dispersao de um liquido numa matriz nao aquosa

Country Status (14)

Country Link
US (1) US4832953A (pt)
EP (1) EP0304227B1 (pt)
JP (1) JP2610314B2 (pt)
KR (1) KR910000411B1 (pt)
AT (1) ATE86126T1 (pt)
AU (1) AU600634B2 (pt)
CA (1) CA1331340C (pt)
DE (1) DE3878781T2 (pt)
DK (1) DK175797B1 (pt)
ES (1) ES2042754T3 (pt)
GR (1) GR3008020T3 (pt)
IE (1) IE61680B1 (pt)
NZ (1) NZ225766A (pt)
PT (1) PT88269B (pt)

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DE4223360C1 (pt) * 1992-07-16 1993-04-08 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
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US5714162A (en) * 1994-09-16 1998-02-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Scopolamine patch
US5662928A (en) * 1995-04-21 1997-09-02 Ciba-Geigy Corporation Method for the prevention or removal of crystalline scopolamine in a non-aqueous matrix of a transdermal system
US5698217A (en) * 1995-05-31 1997-12-16 Minnesota Mining And Manufacturing Company Transdermal drug delivery device containing a desiccant
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
US6238700B1 (en) * 1995-12-01 2001-05-29 Alza Corporation Method for preventing crystal formation in a dispersion of a liquid in a matrix
AU1120097A (en) * 1995-12-01 1997-06-27 Alza Corporation Improved method for preventing crystal formation in a dispersion of a liquid in a matrix
US6007837A (en) * 1996-07-03 1999-12-28 Alza Corporation Drug delivery devices and process of manufacture
KR100483913B1 (ko) * 1996-07-03 2005-09-02 알자 코포레이션 약물송달장치
DE69716737T2 (de) * 1996-07-03 2003-03-20 Alza Corp., Palo Alto Vorrichtungen zur arzneistoffabgabe und herstellungsverfahren
US6174545B1 (en) 1997-07-01 2001-01-16 Alza Corporation Drug delivery devices and process of manufacture
DE19738643C2 (de) 1997-09-04 2001-10-04 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Scopolaminbase und Verfahren zu seiner Herstellung
GB9720470D0 (en) 1997-09-25 1997-11-26 Ethical Pharmaceuticals South Inhibition of crystallization in transdermal devices
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
KR100572539B1 (ko) * 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
CA2313698C (en) * 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
EP1911488A3 (en) 1997-12-11 2008-12-03 Alza Corporation Device for enhancing transdermal agent flux
ATE406935T1 (de) 1997-12-11 2008-09-15 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
JP4215188B2 (ja) 1997-12-22 2009-01-28 インターシア セラピューティクス，インコーポレイティド 薬剤供給を調節するデバイスのための速度調節膜
AU6406299A (en) * 1998-09-29 2000-04-17 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US20070196490A1 (en) * 1999-01-22 2007-08-23 Powderject Research Limited Method of enhancing needleless transdermal powered drug delivery
DE60024312T2 (de) 1999-12-10 2006-08-17 Alza Corp., Mountain View Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür
AR030312A1 (es) * 2000-08-03 2003-08-20 Antares Pharma Ipl Ag Composicion novedosa para la administracion transdermica y/o transmucosica de compuestos activos, que asegura adecuados niveles terapeuticos
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
US7198801B2 (en) * 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
US20040198706A1 (en) * 2003-03-11 2004-10-07 Carrara Dario Norberto R. Methods and formulations for transdermal or transmucosal application of active agents
US20070225379A1 (en) * 2001-08-03 2007-09-27 Carrara Dario Norberto R Transdermal delivery of systemically active central nervous system drugs
US7387788B1 (en) 2003-10-10 2008-06-17 Antares Pharma Ipl Ag Pharmaceutical compositions of nicotine and methods of use thereof
ES2377932T3 (es) 2003-10-10 2012-04-03 Ferring Bv Formulación farmacéutica transdérmica para minimizar los residuos sobre la piel
US7425340B2 (en) * 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
WO2007124250A2 (en) 2006-04-21 2007-11-01 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
US8067399B2 (en) * 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
KR100699582B1 (ko) 2005-07-11 2007-03-23 삼성전기주식회사 출력 버퍼회로
US20080193534A1 (en) * 2005-08-12 2008-08-14 Astrazeneca Ab Process
US7888422B2 (en) 2005-11-09 2011-02-15 Mylan Technologies Inc. Long-wearing removable pressure sensitive adhesive
WO2008067991A2 (en) * 2006-12-08 2008-06-12 Antares Pharma Ipl Ag Skin-friendly drug complexes for transdermal administration
US20080226698A1 (en) * 2007-03-16 2008-09-18 Mylan Technologies, Inc. Amorphous drug transdermal systems, manufacturing methods, and stabilization
EP2465609B1 (en) 2007-06-21 2016-12-28 Gen-Probe Incorporated Method for mixing the contents of a detection chamber
US9017301B2 (en) * 2007-09-04 2015-04-28 Mylan Technologies, Inc. Transdermal drug delivery systems comprising a coated release liner
CN102099020B (zh) * 2008-05-30 2013-09-18 迈兰股份有限公司 稳定的透皮药物递送系统
AU2009302853B2 (en) * 2008-10-06 2014-09-11 Mylan Technologies, Inc. Amorphous rotigotine transdermal system
AU2010246064A1 (en) 2009-05-04 2011-12-22 Zars Pharma, Inc. Methods of treating pains associated with neuroma, nerve entrapment, and other conditions
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
DE102009052972A1 (de) 2009-11-12 2011-09-15 Lts Lohmann Therapie-Systeme Ag Verfahren zur Verhinderung der Kristallisation von Arzneistoffen in einem Polymerfilm
JP5766475B2 (ja) * 2010-03-30 2015-08-19 日東電工株式会社 貼付製剤およびその製造方法
AU2011311255B2 (en) 2010-04-28 2015-10-08 Sorrento Therapeutics, Inc. Method for increasing permeability of an epithelial barrier
CN102985131B (zh) 2010-04-28 2016-06-29 金伯利-克拉克环球有限公司 用于递送siRNA的医疗装置
DK2563453T3 (en) 2010-04-28 2017-05-22 Kimberly Clark Co Nano-patterned medical device with improved cellular interaction and process for its preparation
PT2563450T (pt) 2010-04-28 2017-08-28 Kimberly Clark Co Dispositivo para entrega de medicação para a artrite reumatóide
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
CA2790749A1 (en) * 2011-09-29 2013-03-29 Nitto Denko Corporation Manufacturing method of patch preparation
EP2771059B1 (en) 2011-10-27 2019-07-17 Sorrento Therapeutics, Inc. Transdermal delivery of high viscosity bioactive agents
JP5270035B1 (ja) * 2012-12-06 2013-08-21 久光製薬株式会社 貼付剤及びその製造方法
JP5307931B1 (ja) 2012-12-27 2013-10-02 久光製薬株式会社 貼付剤及びその製造方法
JP5415645B1 (ja) 2013-06-28 2014-02-12 久光製薬株式会社 貼付剤の製造方法、貼付剤及び包装体
DE102018120505A1 (de) * 2017-10-20 2019-04-25 Amw Gmbh Verhinderung der Kristallisation von Wirkstoffen in transdermalen Darreichungssystemen
AU2020240797A1 (en) 2019-03-19 2021-10-21 Nobelpharma Co., Ltd. Pharmaceutical composition having excellent drug absorption into the living body and excellent chemical stability

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US4262003A (en) * 1975-12-08 1981-04-14 Alza Corporation Method and therapeutic system for administering scopolamine transdermally
US4436741A (en) * 1975-12-08 1984-03-13 Alza Corporation Method for administering scopolamine transdermally
US4031894A (en) * 1975-12-08 1977-06-28 Alza Corporation Bandage for transdermally administering scopolamine to prevent nausea
US4230105A (en) * 1978-11-13 1980-10-28 Merck & Co., Inc. Transdermal delivery of drugs
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
US4532244A (en) * 1984-09-06 1985-07-30 Innes Margaret N Method of treating migraine headaches
JPH0742228B2 (ja) * 1985-11-13 1995-05-10 日東電工株式会社 医薬製剤

Also Published As

Publication number Publication date
IE882424L (en) 1989-02-13
KR890003354A (ko) 1989-04-14
DK453488A (da) 1989-02-14
AU600634B2 (en) 1990-08-16
ES2042754T3 (es) 1993-12-16
DE3878781D1 (de) 1993-04-08
DK453488D0 (da) 1988-08-12
AU2060788A (en) 1989-02-16
US4832953A (en) 1989-05-23
DK175797B1 (da) 2005-02-28
GR3008020T3 (pt) 1993-09-30
IE61680B1 (en) 1994-11-16
JP2610314B2 (ja) 1997-05-14
KR910000411B1 (ko) 1991-01-25
PT88269B (pt) 1996-01-31
EP0304227A3 (en) 1989-06-28
CA1331340C (en) 1994-08-09
EP0304227B1 (en) 1993-03-03
DE3878781T2 (de) 1993-06-09
JPS6466113A (en) 1989-03-13
NZ225766A (en) 1990-06-26
ATE86126T1 (de) 1993-03-15
EP0304227A2 (en) 1989-02-22

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19951027

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20101027