PT88245A - Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos - Google Patents

Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos

Info

Publication number
PT88245A
PT88245A PT88245A PT8824588A PT88245A PT 88245 A PT88245 A PT 88245A PT 88245 A PT88245 A PT 88245A PT 8824588 A PT8824588 A PT 8824588A PT 88245 A PT88245 A PT 88245A
Authority
PT
Portugal
Prior art keywords
alkyl
formula
phenyl
hydrogen atom
group
Prior art date
Application number
PT88245A
Other languages
English (en)
Other versions
PT88245B (pt
Inventor
Francis Patrick Carr
Robert Delane Dillard
Winston Stanley Marshall
Doris Elfriede Mccullough
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT88245A publication Critical patent/PT88245A/pt
Publication of PT88245B publication Critical patent/PT88245B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT88245A 1987-08-14 1988-08-11 Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos PT88245B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/085,586 US4820722A (en) 1987-08-14 1987-08-14 Disubstituted tetrazoles and their use as leukotriene antagonists

Publications (2)

Publication Number Publication Date
PT88245A true PT88245A (pt) 1989-06-30
PT88245B PT88245B (pt) 1995-03-01

Family

ID=22192620

Family Applications (1)

Application Number Title Priority Date Filing Date
PT88245A PT88245B (pt) 1987-08-14 1988-08-11 Processo para a preparacao de derivados de tetrazole antagonistas de leucotrienos

Country Status (13)

Country Link
US (1) US4820722A (pt)
EP (1) EP0305085B1 (pt)
JP (1) JPS6466175A (pt)
KR (1) KR890003715A (pt)
CN (1) CN1013769B (pt)
AT (1) ATE92052T1 (pt)
AU (1) AU610629B2 (pt)
DE (1) DE3882619T2 (pt)
DK (1) DK449488A (pt)
HU (1) HUT50463A (pt)
NZ (1) NZ225793A (pt)
PT (1) PT88245B (pt)
ZA (1) ZA885888B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
IL98405A0 (en) * 1990-06-11 1992-07-15 Fmc Corp Pharmaceutical compositions containing enzyme inhibiting agents
US5210208A (en) * 1990-09-24 1993-05-11 Rhone-Poulenc Rorer Pharmaceuticals Inc. Disubstituted aryl compounds exhibiting selective leukotriene b4 antagonist activity
DE4124942A1 (de) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
PT85110A (en) * 1986-06-23 1987-07-01 Merck Frosst Canada Inc Process for preparing benzenealkanoic acid derivatives useful as leukotriene antagonists
US4820723A (en) * 1987-08-14 1989-04-11 Eli Lilly And Company Disubstituted tetrazole leukotriene antagonists and methods for their use thereas

Also Published As

Publication number Publication date
PT88245B (pt) 1995-03-01
HUT50463A (en) 1990-02-28
US4820722A (en) 1989-04-11
DK449488D0 (da) 1988-08-11
CN1013769B (zh) 1991-09-04
DE3882619D1 (de) 1993-09-02
EP0305085B1 (en) 1993-07-28
CN1031223A (zh) 1989-02-22
EP0305085A1 (en) 1989-03-01
AU2096688A (en) 1989-02-16
DK449488A (da) 1989-03-17
AU610629B2 (en) 1991-05-23
JPS6466175A (en) 1989-03-13
NZ225793A (en) 1990-10-26
KR890003715A (ko) 1989-04-17
ZA885888B (en) 1990-04-25
DE3882619T2 (de) 1993-12-23
ATE92052T1 (de) 1993-08-15

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940808

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960229