DE3882619D1 - Leukotrien-antagonisten. - Google Patents

Leukotrien-antagonisten.

Info

Publication number
DE3882619D1
DE3882619D1 DE8888307430T DE3882619T DE3882619D1 DE 3882619 D1 DE3882619 D1 DE 3882619D1 DE 8888307430 T DE8888307430 T DE 8888307430T DE 3882619 T DE3882619 T DE 3882619T DE 3882619 D1 DE3882619 D1 DE 3882619D1
Authority
DE
Germany
Prior art keywords
alkyl
formula
phenyl
hydrogen atom
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888307430T
Other languages
English (en)
Other versions
DE3882619T2 (de
Inventor
Francis Patrick Carr
Robert Delane Dillard
Winston Stanley Marshall
Doris Elfriede Mccullough
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE3882619D1 publication Critical patent/DE3882619D1/de
Application granted granted Critical
Publication of DE3882619T2 publication Critical patent/DE3882619T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE88307430T 1987-08-14 1988-08-11 Leukotrien-Antagonisten. Expired - Fee Related DE3882619T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/085,586 US4820722A (en) 1987-08-14 1987-08-14 Disubstituted tetrazoles and their use as leukotriene antagonists

Publications (2)

Publication Number Publication Date
DE3882619D1 true DE3882619D1 (de) 1993-09-02
DE3882619T2 DE3882619T2 (de) 1993-12-23

Family

ID=22192620

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88307430T Expired - Fee Related DE3882619T2 (de) 1987-08-14 1988-08-11 Leukotrien-Antagonisten.

Country Status (13)

Country Link
US (1) US4820722A (de)
EP (1) EP0305085B1 (de)
JP (1) JPS6466175A (de)
KR (1) KR890003715A (de)
CN (1) CN1013769B (de)
AT (1) ATE92052T1 (de)
AU (1) AU610629B2 (de)
DE (1) DE3882619T2 (de)
DK (1) DK449488A (de)
HU (1) HUT50463A (de)
NZ (1) NZ225793A (de)
PT (1) PT88245B (de)
ZA (1) ZA885888B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
IL98405A0 (en) * 1990-06-11 1992-07-15 Fmc Corp Pharmaceutical compositions containing enzyme inhibiting agents
US5210208A (en) * 1990-09-24 1993-05-11 Rhone-Poulenc Rorer Pharmaceuticals Inc. Disubstituted aryl compounds exhibiting selective leukotriene b4 antagonist activity
DE4124942A1 (de) * 1991-07-27 1993-01-28 Thomae Gmbh Dr K 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
PT85110A (en) * 1986-06-23 1987-07-01 Merck Frosst Canada Inc Process for preparing benzenealkanoic acid derivatives useful as leukotriene antagonists
US4820723A (en) * 1987-08-14 1989-04-11 Eli Lilly And Company Disubstituted tetrazole leukotriene antagonists and methods for their use thereas

Also Published As

Publication number Publication date
CN1013769B (zh) 1991-09-04
KR890003715A (ko) 1989-04-17
CN1031223A (zh) 1989-02-22
AU2096688A (en) 1989-02-16
PT88245A (pt) 1989-06-30
EP0305085B1 (de) 1993-07-28
ZA885888B (en) 1990-04-25
US4820722A (en) 1989-04-11
NZ225793A (en) 1990-10-26
DK449488A (da) 1989-03-17
HUT50463A (en) 1990-02-28
DE3882619T2 (de) 1993-12-23
PT88245B (pt) 1995-03-01
EP0305085A1 (de) 1989-03-01
AU610629B2 (en) 1991-05-23
JPS6466175A (en) 1989-03-13
ATE92052T1 (de) 1993-08-15
DK449488D0 (da) 1988-08-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee