PT87377A - Method for the treatment of withdrawal symptoms associated with smoking cessation and preparations for use in said method - Google Patents

Method for the treatment of withdrawal symptoms associated with smoking cessation and preparations for use in said method

Info

Publication number
PT87377A
PT87377A PT87377A PT8737788A PT87377A PT 87377 A PT87377 A PT 87377A PT 87377 A PT87377 A PT 87377A PT 8737788 A PT8737788 A PT 8737788A PT 87377 A PT87377 A PT 87377A
Authority
PT
Portugal
Prior art keywords
solid
symptoms associated
semi
mixture
withdrawal symptoms
Prior art date
Application number
PT87377A
Other languages
English (en)
Other versions
PT87377B (pt
Inventor
Yvonne Brigid Bannon
John Corish
Owen Ignatius Corrigan
Edward James Geoghegan
Joseph G Masterson
Original Assignee
Elan Transdermal Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26319051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT87377(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IE1119/87A external-priority patent/IE57786B1/en
Application filed by Elan Transdermal Ltd filed Critical Elan Transdermal Ltd
Publication of PT87377A publication Critical patent/PT87377A/pt
Publication of PT87377B publication Critical patent/PT87377B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Addiction (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
PT87377A 1987-05-01 1988-04-29 Processo para a preparacao de uma composicao farmaceutica contendo nicotina PT87377B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE1119/87A IE57786B1 (en) 1987-07-17 1987-05-01 Method for the treatment of withdrawal symptoms associated with smoking cessation and preparations for use in said method
IE194687 1987-07-17

Publications (2)

Publication Number Publication Date
PT87377A true PT87377A (pt) 1989-05-31
PT87377B PT87377B (pt) 1992-08-31

Family

ID=26319051

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87377A PT87377B (pt) 1987-05-01 1988-04-29 Processo para a preparacao de uma composicao farmaceutica contendo nicotina

Country Status (14)

Country Link
US (2) US4946853A (pt)
EP (1) EP0289342B1 (pt)
JP (1) JPS646216A (pt)
AT (1) ATE161721T1 (pt)
CA (1) CA1333051C (pt)
DE (1) DE3856096T2 (pt)
DK (1) DK235088A (pt)
ES (1) ES2112241T3 (pt)
GR (1) GR3026563T3 (pt)
IL (1) IL86170A (pt)
NO (1) NO179963C (pt)
NZ (1) NZ224426A (pt)
PH (1) PH24437A (pt)
PT (1) PT87377B (pt)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908027A (en) * 1986-09-12 1990-03-13 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
US5344656A (en) * 1986-09-12 1994-09-06 Alza Corporation Subsaturated transdermal therapeutic system having improved release characteristics
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
US5004610A (en) * 1988-06-14 1991-04-02 Alza Corporation Subsaturated nicotine transdermal therapeutic system
IE62662B1 (en) * 1989-01-06 1995-02-22 Elan Corp Plc Use of nicotine in the treatment of conditions susceptible to said treatment
US4908213A (en) * 1989-02-21 1990-03-13 Schering Corporation Transdermal delivery of nicotine
JPH02258718A (ja) * 1989-03-31 1990-10-19 Nippon Kayaku Co Ltd ペースト状基剤及び製剤
US5652214A (en) * 1989-06-05 1997-07-29 Cephalon, Inc. Treating disorders by application of insulin-like growth factors and analogs
US5095109A (en) * 1989-06-08 1992-03-10 University Of Vermont Novel alkaloids
FR2650747B1 (fr) * 1989-08-11 1994-02-11 Oreal Film composite pour traitement cutane local et procedes de fabrication correspondants
US5230896A (en) * 1989-10-12 1993-07-27 Warner-Lambert Company Transdermal nicotine delivery system
US5525351A (en) * 1989-11-07 1996-06-11 Dam; Anders Nicotine containing stimulant unit
US5077104A (en) * 1989-12-21 1991-12-31 Alza Corporation Nicotine packaging materials
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
JP2849937B2 (ja) * 1990-04-18 1999-01-27 日東電工株式会社 医療用貼付剤
US5484604A (en) * 1990-07-21 1996-01-16 Chatfield Pharmaceuticals Limited Cross-linked alginate transdermal medicine delivery devices
GB9016056D0 (en) * 1990-07-21 1990-09-05 Chatfield Pharmaceuticals Limi Transdermal medicine delivery devices
US5135753A (en) * 1991-03-12 1992-08-04 Pharmetrix Corporation Method and therapeutic system for smoking cessation
US5486362A (en) * 1991-05-07 1996-01-23 Dynagen, Inc. Controlled, sustained release delivery system for treating drug dependency
US5629019A (en) * 1992-02-27 1997-05-13 Alza Corporation Formulations with hydrophobic permeation enhancers
US5596007A (en) * 1992-05-18 1997-01-21 Pharmaco Behavioral Associates, Inc. Therapeutic method to alleviate the craving associated with cessation of tobacco with cotinine
US5643928A (en) * 1992-10-21 1997-07-01 Pharmaco Behavioral Associates, Inc. Human body weight management
US5869505A (en) * 1993-02-02 1999-02-09 Keenan; Robert M. Nicotine metabolites and nicotine dependence
CA2142871A1 (en) * 1992-08-25 1994-03-03 Jesus Miranda Printed transdermal drug delivery device
US5573774A (en) * 1993-02-02 1996-11-12 Keenan; Robert M. Nicotine metabolites, nicotine dependence and human body weight
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
CA2164109C (en) * 1993-06-23 2005-09-27 John J. Masiz Molecular transdermal transport system
EP0708627B1 (en) * 1993-07-09 2000-02-02 Cygnus, Inc. Method and device for providing nicotine replacement therapy transdermally/transbuccally
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
DE4440563A1 (de) * 1994-11-12 1996-05-15 Herzog Sen Rolf Verfahren und Mittel zum Genuß von Tabak - Nikotin unter Vermeidung schädlicher Verbrennungs - Derivate
US5691365A (en) * 1995-07-18 1997-11-25 University Of Kentucky Research Foundation Nicotinic receptor antagonists in the treatment of neuropharmacological disorders
US5716635A (en) * 1995-07-19 1998-02-10 M. E. Cody Products, Inc. Plantago major transdermal patch for use in treating a tobacco or nicotine habit
US6245347B1 (en) * 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US5776956A (en) * 1996-07-30 1998-07-07 Lectec Corporation Use of cotinine in treating psychiatric disorders
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
SE9703458D0 (sv) * 1997-09-25 1997-09-25 Pharmacia & Upjohn Ab Nicotine compositions and methods of formulation thereof
DE19746191C2 (de) * 1997-10-18 2000-05-18 Lohmann Therapie Syst Lts Verfahren zur Anwendung eines Wirkstoff enthaltenden Pflasters zur Bekämpfung oder Linderung einer Sucht
US20020098264A1 (en) * 1998-11-27 2002-07-25 Cherukuri Subraman R. Medicated chewing gum delivery system for nicotine
US6358060B2 (en) * 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
AU6406299A (en) * 1998-09-29 2000-04-17 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
CN1331586A (zh) 1998-12-18 2002-01-16 阿尔扎有限公司 透明的透皮烟碱输送装置
US8188043B2 (en) * 1999-07-28 2012-05-29 The Board Of Trustees Of The Leland Stanford Jr. University Nicotine in therapeutic angiogenesis and vasculogenesis
US6974588B1 (en) * 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
WO2001051089A1 (de) * 2000-01-13 2001-07-19 Merck Patent Gmbh Pharmazeutische zubereitungen enthaltend 2-pyrrolidon als lösungsvermittler
US6635274B1 (en) 2000-10-27 2003-10-21 Biochemics, Inc. Solution-based transdermal drug delivery system
CA2423930C (en) * 2000-10-27 2009-11-24 Leo Pharma A/S Topical composition containing at least one vitamin d or one vitamin d analogue and at least one corticosteroid
EP1372708B1 (en) 2001-02-13 2008-06-18 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE ARMY Vaccine for transcutaneous immunization against travellers' diarrhoea
EP1462099A4 (en) * 2001-12-13 2007-12-26 Dia Pharmaceutical Co Ltd GEL COMPOSITIONS FOR EXTERNAL APPLICATION, UPHOLSTERY MATERIALS AND UPHOLSTERED POLTER MATERIALS
US7105173B1 (en) 2002-03-21 2006-09-12 Rolling Kenneth J Nicotine replacement applique
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
US20050282977A1 (en) * 2004-06-17 2005-12-22 Emil Stempel Cross-linked gel and pressure sensitive adhesive blend, and skin-attachable products using the same
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
IL177071A0 (en) * 2005-08-01 2006-12-10 Nitto Denko Corp Method of preparing a nicotine transdermal preparation
EP1774964B1 (en) * 2005-10-13 2014-08-06 Nitto Denko Corporation Nicotine transdermal preparation and production method thereof
SE530256C2 (sv) * 2005-12-16 2008-04-15 Moelnlycke Health Care Ab Metod för att uppta hål i värmesmältbara material
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
WO2007112581A1 (en) 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US8642016B2 (en) * 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US20080230078A1 (en) * 2007-03-19 2008-09-25 Oby George Tolman Method of smoking cessation
US20080287507A1 (en) * 2007-05-16 2008-11-20 John Hedenstrom Nicotine containing toiletry waters
EP2413837A4 (en) * 2009-04-01 2013-10-23 Jie Zhang METHODS FOR TREATING MYOFASCIAL, MUSCLE AND / OR BACK PAIN
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
EP2427160A4 (en) * 2009-05-04 2012-12-19 Zars Pharma Inc METHOD FOR TREATING PAIN RELATED TO NEUROMAS, NERVE CLAIMS AND OTHER SUFFERING PAINS
KR101670379B1 (ko) * 2009-07-31 2016-10-28 (주)씨엘팜 니코틴 경피 전달 패취
KR101746204B1 (ko) * 2010-02-18 2017-06-13 에스케이케미칼주식회사 피부 투과가 개선된 톨테로딘의 경피 투여용 조성물
KR20110094858A (ko) * 2010-02-18 2011-08-24 에스케이케미칼주식회사 피부 자극이 감소한 톨테로딘의 경피 투여용 조성물
WO2011117740A2 (en) 2010-03-26 2011-09-29 Philip Morris Products S.A. Inhibition of sensory irritation during consumption of non-smokeable tobacco products
US8952038B2 (en) 2010-03-26 2015-02-10 Philip Morris Usa Inc. Inhibition of undesired sensory effects by the compound camphor
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
PL2672847T3 (pl) 2011-02-11 2015-10-30 Batmark Ltd Część składowa inhalatora
BR112013028802B1 (pt) 2011-05-10 2021-10-26 Itochu Chemical Frontier Corporation Curativo adesivo não-aquoso
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
US9925264B2 (en) 2011-05-10 2018-03-27 Itochu Chemical Frontier Corporation Non-aqueous patch
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
LT2823815T (lt) 2011-09-27 2018-08-27 Itochu Chemical Frontier Corporation Nevandeninis pleistras
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
CN104411297B (zh) 2012-03-27 2017-10-24 尼科辛诺公司 尼古丁制剂
US10799451B2 (en) 2012-03-27 2020-10-13 Nicoccino Ab Nicotine formulation
US10335378B2 (en) 2013-03-15 2019-07-02 Altria Client Services Llc Inhibition of central nervous system effects from smoking and sensory effects from smoking
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
WO2016069875A1 (en) 2014-10-30 2016-05-06 Arena Pharmaceuticals, Inc. Compositions and methods for ceasing tobacco smoking
GB2535427A (en) 2014-11-07 2016-08-24 Nicoventures Holdings Ltd Solution
BR112017023088B1 (pt) 2015-04-27 2023-10-03 Arena Pharmaceuticals, Inc Compostos agonistas do receptor 5-ht2c, composição farmacêutica,seu processo de preparação e seus usos
EP3346998A4 (en) * 2015-08-17 2019-08-28 Sidmak Laboratories (India) PVT. Ltd. TOPIC FILM DELIVERY SYSTEM
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
EA038219B1 (ru) 2016-08-19 2021-07-26 Арена Фармасьютикалз, Инк. Агонисты рецептора 5-ht2c и композиции, а также способ их применения
GB201718031D0 (en) 2017-11-01 2017-12-13 British American Tobacco Investments Ltd Aerosolisable gel
BR112020025604A2 (pt) 2018-06-15 2021-03-23 R.J. Reynolds Tobacco Company purificação de nicotina

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3901248A (en) * 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3877468A (en) * 1970-07-22 1975-04-15 Leo Ab Chewable tobacco substitute composition
US3731683A (en) * 1971-06-04 1973-05-08 Alza Corp Bandage for the controlled metering of topical drugs to the skin
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
US4675009A (en) * 1977-11-07 1987-06-23 Lec Tec Corporation Drug dispensing device for transdermal delivery of medicaments
IL59063A (en) * 1979-01-11 1983-12-30 Key Pharma Polymeric diffusion matrix for release of pharmaceutical dosage
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4336243A (en) * 1980-08-11 1982-06-22 G. D. Searle & Co. Transdermal nitroglycerin pad
IE53703B1 (en) * 1982-12-13 1989-01-18 Elan Corp Plc Drug delivery device
IE54286B1 (en) * 1983-01-18 1989-08-16 Elan Corp Plc Drug delivery device
JPS6094209A (ja) * 1983-10-31 1985-05-27 Toyoda Mach Works Ltd コレツトチヤツクによる工作物保持装置
US4624665A (en) * 1984-10-01 1986-11-25 Biotek, Inc. Method of transdermal drug delivery
US4687481A (en) * 1984-10-01 1987-08-18 Biotek, Inc. Transdermal drug delivery system
EP0177329B1 (en) * 1984-10-05 1992-09-30 Hercon Laboratories Corporation Device for transdermal drug administration
DE3438284A1 (de) * 1984-10-16 1985-03-07 Hans-Harald von 2400 Lübeck Tilly Nikotinhaltiges depotpflaster
US4597961A (en) * 1985-01-23 1986-07-01 Etscorn Frank T Transcutaneous application of nicotine
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4665069A (en) * 1985-04-02 1987-05-12 Barnett Rosenberg Analgesic composition and method of relieving pain
US5016652A (en) * 1985-04-25 1991-05-21 The Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US4953572A (en) * 1985-04-25 1990-09-04 Rose Jed E Method and apparatus for aiding in the reduction of incidence of tobacco smoking
US4920989A (en) * 1985-04-25 1990-05-01 Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
JPS61251619A (ja) * 1985-04-30 1986-11-08 Nitto Electric Ind Co Ltd ニコチン含有テ−プ製剤
US4821745A (en) * 1985-11-14 1989-04-18 Rosen David I Apparatus and method for overcoming the habit of tobacco smoking
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
CA1273878A (en) * 1987-01-15 1990-09-11 Richard Philip Moody Nicotine-containing preparation for transdermal administration
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
US4839174A (en) * 1987-10-05 1989-06-13 Pharmetrix Corporation Novel transdermal nicotine patch

Also Published As

Publication number Publication date
NO881910L (no) 1988-11-02
EP0289342B1 (en) 1998-01-07
DE3856096T2 (de) 1998-07-09
ES2112241T3 (es) 1998-04-01
NO179963C (no) 1997-01-22
NZ224426A (en) 1990-12-21
GR3026563T3 (en) 1998-07-31
IL86170A0 (en) 1988-11-15
NO881910D0 (no) 1988-04-29
EP0289342A2 (en) 1988-11-02
AU1534988A (en) 1988-11-03
NO179963B (no) 1996-10-14
JPS646216A (en) 1989-01-10
ATE161721T1 (de) 1998-01-15
PT87377B (pt) 1992-08-31
EP0289342A3 (en) 1989-01-25
DK235088A (da) 1989-01-10
PH24437A (en) 1990-06-25
AU607214B2 (en) 1991-02-28
DK235088D0 (da) 1988-04-28
CA1333051C (en) 1994-11-15
IL86170A (en) 1992-12-01
DE3856096D1 (de) 1998-02-12
US4946853A (en) 1990-08-07
US5298257A (en) 1994-03-29

Similar Documents

Publication Publication Date Title
PT87377A (pt) Method for the treatment of withdrawal symptoms associated with smoking cessation and preparations for use in said method
GB8401965D0 (en) Composition
ATE20518T1 (de) Trockene pulverige allergenzusammensetzung und verfahren zu deren herstellung.
SE8402550D0 (sv) N-substituerade deriavat av moranolin
ATE56365T1 (de) Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung.
DE58901002D1 (de) Mittel mit zerstoerender wirkung auf maligne tumore, verfahren zu dessen herstellung und praeparation zur anwendung in der therapie von krebskranken.
ATE51343T1 (de) Abwaschbare topische zubereitung zur therapie der psoriasis.
SE7601535L (sv) Injicerbara antibiotiska kompositioner
IE873348L (en) Compositions for topical application
TW269636B (en) Once-daily transdermal pharmaceutical composition of nicotine for the treatment of withdrawal symptoms associated with smoking cessation
KR890007728A (ko) 진통제 제조방법
KR900017599A (ko) 종양 치료용 약학 조성물
KR880002521A (ko) 약제 제형
Pozuels Suppression of craving and withdrawal in humans addicted to narcotics or amphetamines by administration of alpha-methyl-para-tyrosine (AMPT) and 5-butylpicolinic acid (fusaric acid) treatment of narcotic and amphetamine addiction in humans: preliminary report
KR870005642A (ko) 디플루니살과 트로메타민의 혼합물
FR2300574A2 (fr) Composition a base d'huile vegetale metabolisab
JPS5261217A (en) Method for increasing absorption of novel penicillin at rectal infusio n
GB2019720A (en) S-adenosyl-L-homocysteine and salts thereof for use in therapy
KR890001567A (ko) 디플루니살 및 트로메타민-함유 조성물
OA05887A (fr) Dérivés d'acides méthyl-2 phénoxy-2 propioniques, leur procédé de préparation et leurs applications en thérapeutique.
EP0307390A3 (de) Chemische Verbindung bestehend aus cis-3-hydroxyprolin zur therapeutischen Behandlung und Verfahren zu deren Herstellung
RU96117923A (ru) Способ лечения хронических сальпингоофоритов
JPS5699420A (en) Immune reactivator
EP0323147A3 (en) 1-aralkyl-1,2-dihydropyrimidine-2-thiones

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920213

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040813