PT831938E - Composições de peptídeos radiomarcados para alvejamento específico de um sítio - Google Patents

Composições de peptídeos radiomarcados para alvejamento específico de um sítio Download PDF

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Publication number
PT831938E
PT831938E PT96922403T PT96922403T PT831938E PT 831938 E PT831938 E PT 831938E PT 96922403 T PT96922403 T PT 96922403T PT 96922403 T PT96922403 T PT 96922403T PT 831938 E PT831938 E PT 831938E
Authority
PT
Portugal
Prior art keywords
somatostatin
peptide
radiolabeled peptide
radiolabeled
diagnostic
Prior art date
Application number
PT96922403T
Other languages
English (en)
Portuguese (pt)
Inventor
Ananthachari Srinivasan
Jack L Erion
Mary Marmion Dyszlewski
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23907713&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT831938(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of PT831938E publication Critical patent/PT831938E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PT96922403T 1995-06-07 1996-06-06 Composições de peptídeos radiomarcados para alvejamento específico de um sítio PT831938E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/480,373 US5830431A (en) 1995-06-07 1995-06-07 Radiolabeled peptide compositions for site-specific targeting

Publications (1)

Publication Number Publication Date
PT831938E true PT831938E (pt) 2008-08-26

Family

ID=23907713

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96922403T PT831938E (pt) 1995-06-07 1996-06-06 Composições de peptídeos radiomarcados para alvejamento específico de um sítio

Country Status (10)

Country Link
US (2) US5830431A (fr)
EP (2) EP0831938B1 (fr)
JP (2) JP4236282B2 (fr)
AT (1) ATE395938T1 (fr)
CA (1) CA2224153C (fr)
DE (1) DE69637535D1 (fr)
DK (2) DK1872800T3 (fr)
ES (2) ES2395961T3 (fr)
PT (1) PT831938E (fr)
WO (1) WO1996040291A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
MY133346A (en) 1999-03-01 2007-11-30 Biogen Inc Kit for radiolabeling ligands with yttrium-90
US20020102208A1 (en) 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
CA2410906C (fr) * 2000-06-02 2012-10-02 Board Of Regents, The University Of Texas System Conjugues ethylenedicysteine (ec)-medicament
CA2444483A1 (fr) * 2001-04-26 2002-11-07 Board Of Regents, The University Of Texas System Compositions d'imagerie diagnostique, leurs methodes de synthese et utilisation
US7261875B2 (en) * 2001-12-21 2007-08-28 Board Of Regents, The University Of Texas System Dendritic poly (amino acid) carriers and methods of use
EP2316493A3 (fr) * 2002-11-07 2011-08-10 Board of Regents, The University of Texas System Conjugués ethylène dicysteine (ec)-médicament, compositions et procédés d'imagerie de maladies spécifiques des tissus
WO2004081031A2 (fr) * 2003-03-10 2004-09-23 Biogen Idec Inc. Fixation de medicament a mediation de thiol a des peptides de ciblage
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
EP1861127A1 (fr) * 2005-03-10 2007-12-05 Bayer Schering Pharma Aktiengesellschaft Chelateurs pour des conjugues radioactivement marques comprenant une chaine laterale stabilisante
US8758723B2 (en) * 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) * 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
WO2011075678A1 (fr) 2009-12-18 2011-06-23 The Board Of Trustees Of The Leland Stanford Junior University Inhibiteurs spécifiques et sondes de site actif pour la légumaïne
EP2889295A1 (fr) 2010-08-12 2015-07-01 New York University Oligooxopiperazines et procédés de fabrication et d'utilisation de celles-ci
US9255086B2 (en) 2012-02-16 2016-02-09 New York University Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics
CN104768573B (zh) * 2012-05-08 2017-08-29 Trt创新有限责任公司 用于位点特异性uPAR靶向的177‑Lu标记肽
MX2017016863A (es) 2015-06-25 2018-09-06 Advanced Accelerator Applications Metodo de tratamiento de tumores neuroendocrinos que sobreexpresan receptores de somatostatatina.
ES2960030T3 (es) 2017-01-12 2024-02-29 Radiomedix Inc Tratamiento de células cancerosas que sobreexpresan receptores de somatostatina utilizando derivados de ocreótido quelados con radioisótopos
US10596278B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
WO2020056064A1 (fr) 2018-09-11 2020-03-19 Stanley Satz Thérapie par radionucléides ciblée antitumorale et imagerie moléculaire de cancers her2 + et d'autres néoplasmes, et médicament de précision

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19375086I2 (de) * 1979-11-27 2003-01-09 Novartis Ag Polypeptide Verfahren zu ihrer Herstellung pharmazeutische Zusammensetzungen die diese Polypeptide enthalten und ihre Verwendung
US4282143A (en) * 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone
US4440904A (en) * 1983-01-31 1984-04-03 American Home Products Corporation Nonapeptide anti-secretory agents
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4585755A (en) * 1985-04-29 1986-04-29 Merck & Co., Inc. Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
JPH04236282A (ja) * 1991-01-18 1992-08-25 Aica Kogyo Co Ltd 接着剤組成物
EP0600992B1 (fr) * 1991-08-29 2000-09-20 Mallinckrodt Medical, Inc. Utilisation de l'acide gentisique ou de l'alcool gentisyle pour stabiliser des peptides et proteines radiomarques
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5411943A (en) * 1992-02-25 1995-05-02 Biomeasure, Inc. Hepatoma treatment with somatostatin analogs
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
CA2113121A1 (fr) * 1993-01-12 1994-07-13 Rainer Albert Peptides
KR100325972B1 (ko) * 1993-08-09 2002-07-27 바이오메져 인코퍼레이티드 치료성펩타이드유도체
DE69434810T2 (de) * 1993-11-16 2007-08-02 Bracco International B.V. Immobilisiertes markierungsverfahren
EP0738158B1 (fr) * 1994-01-12 2002-04-03 Amersham plc Agents biologiques de ciblage
EP0835662B1 (fr) * 1996-10-08 2001-11-14 National Institute of Immunology Médicament pour le traitement du cancer

Also Published As

Publication number Publication date
ES2308778T3 (es) 2008-12-01
EP1872800A3 (fr) 2008-03-19
JPH11507342A (ja) 1999-06-29
CA2224153A1 (fr) 1996-12-19
CA2224153C (fr) 2010-08-17
DK1872800T3 (da) 2013-02-04
DE69637535D1 (de) 2008-07-03
ATE395938T1 (de) 2008-06-15
EP1872800B1 (fr) 2012-10-17
ES2395961T3 (es) 2013-02-18
EP0831938A4 (fr) 2001-12-05
US5804157A (en) 1998-09-08
DK0831938T3 (da) 2008-07-21
JP4236282B2 (ja) 2009-03-11
EP1872800A2 (fr) 2008-01-02
WO1996040291A1 (fr) 1996-12-19
EP0831938B1 (fr) 2008-05-21
EP0831938A1 (fr) 1998-04-01
US5830431A (en) 1998-11-03
JP2008266342A (ja) 2008-11-06

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