DK1872800T3 - Radiomærkede peptidsammensætninger til stedsspecifik målsøgning - Google Patents

Radiomærkede peptidsammensætninger til stedsspecifik målsøgning

Info

Publication number
DK1872800T3
DK1872800T3 DK07019899.9T DK07019899T DK1872800T3 DK 1872800 T3 DK1872800 T3 DK 1872800T3 DK 07019899 T DK07019899 T DK 07019899T DK 1872800 T3 DK1872800 T3 DK 1872800T3
Authority
DK
Denmark
Prior art keywords
somatostatin
peptide
radiolabeled peptide
radiolabeled
diagnostic
Prior art date
Application number
DK07019899.9T
Other languages
English (en)
Inventor
Mary Marmion Dyszlewski
Jack L Erion
Ananthachari Srinivasan
Joseph E Bugaj
Original Assignee
Mallinckrodt Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23907713&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1872800(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mallinckrodt Llc filed Critical Mallinckrodt Llc
Application granted granted Critical
Publication of DK1872800T3 publication Critical patent/DK1872800T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK07019899.9T 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedsspecifik målsøgning DK1872800T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/480,373 US5830431A (en) 1995-06-07 1995-06-07 Radiolabeled peptide compositions for site-specific targeting
EP96922403A EP0831938B1 (en) 1995-06-07 1996-06-06 Radiolabeled peptide compositions for site-specific targeting

Publications (1)

Publication Number Publication Date
DK1872800T3 true DK1872800T3 (da) 2013-02-04

Family

ID=23907713

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07019899.9T DK1872800T3 (da) 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedsspecifik målsøgning
DK96922403T DK0831938T3 (da) 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedspecifik målsögninger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK96922403T DK0831938T3 (da) 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedspecifik målsögninger

Country Status (10)

Country Link
US (2) US5830431A (da)
EP (2) EP1872800B1 (da)
JP (2) JP4236282B2 (da)
AT (1) ATE395938T1 (da)
CA (1) CA2224153C (da)
DE (1) DE69637535D1 (da)
DK (2) DK1872800T3 (da)
ES (2) ES2395961T3 (da)
PT (1) PT831938E (da)
WO (1) WO1996040291A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
MY133346A (en) 1999-03-01 2007-11-30 Biogen Inc Kit for radiolabeling ligands with yttrium-90
US20020102208A1 (en) 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
US7067111B1 (en) 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
JP5448284B2 (ja) * 2000-06-02 2014-03-19 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム エチレンジシステイン(ec)−薬物結合体
CA2444483A1 (en) * 2001-04-26 2002-11-07 Board Of Regents, The University Of Texas System Diagnostic imaging compositions, their methods of synthesis and use
US7261875B2 (en) * 2001-12-21 2007-08-28 Board Of Regents, The University Of Texas System Dendritic poly (amino acid) carriers and methods of use
PL377107A1 (pl) * 2002-11-07 2006-01-23 Board Of Regents, The University Of Texas System Koniugaty etylenodicysteiny (EC) z lekiem, kompozycje oraz sposoby obrazowania tkankowo specyficznych chorób
AU2004220104A1 (en) * 2003-03-10 2004-09-23 Biogen Idec Inc. Thiol-mediated drug attachment to targeting peptides
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
EP1861127A1 (en) * 2005-03-10 2007-12-05 Bayer Schering Pharma Aktiengesellschaft Chelators for radioactively labeled conjugates comprising a stabilizing sidechain
US8758723B2 (en) * 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
US9345789B2 (en) 2009-12-18 2016-05-24 The Board Of Trustees Of The Leland Stanford Junior University Specific inhibitors and active site probes for legumain
EP2889295A1 (en) 2010-08-12 2015-07-01 New York University Oligooxopiperazines and methods of making and using them
CN104334541A (zh) 2012-02-16 2015-02-04 纽约大学 使用低聚氧代哌嗪非肽螺旋模拟物对低氧诱导基因表达的控制
JP2015532636A (ja) 2012-05-08 2015-11-12 リグスホスピタレト 部位特異的uPAR標的化のための177−Lu標識ペプチド
SG10201913964QA (en) 2015-06-25 2020-03-30 Advanced Accelerator Applications Method of treatment of neuroendocrine tumors that over-express somatostatatin receptors
PL3568205T3 (pl) 2017-01-12 2024-03-18 Radiomedix Inc. Leczenie komórek nowotworowych z nadekspresją receptorów somatostatyny z użyciem pochodnych okreotydu chelatowanych z radioizotopami
US10596278B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US20200085979A1 (en) 2018-09-11 2020-03-19 Stanley Satz Precision medicine theranostics and diagnostics a combination thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029579B1 (en) * 1979-11-27 1983-02-16 Sandoz Ag Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
US4282143A (en) * 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone
US4440904A (en) * 1983-01-31 1984-04-03 American Home Products Corporation Nonapeptide anti-secretory agents
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4585755A (en) * 1985-04-29 1986-04-29 Merck & Co., Inc. Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
JPH04236282A (ja) * 1991-01-18 1992-08-25 Aica Kogyo Co Ltd 接着剤組成物
EP0600992B1 (en) * 1991-08-29 2000-09-20 Mallinckrodt Medical, Inc. Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5411943A (en) * 1992-02-25 1995-05-02 Biomeasure, Inc. Hepatoma treatment with somatostatin analogs
NZ250653A (en) * 1993-01-12 1995-12-21 Sandoz Ltd Somatostatin derivatives and pharmaceutical or diagnostic imaging compositions
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
UA44707C2 (uk) * 1993-08-09 2002-03-15 Біомежер, Інк. Похідні пептидів та спосіб лікування раку
EP0730472B1 (en) * 1993-11-16 2006-08-02 Bracco International B.V. Immobilized labelling method
EP0738158B1 (en) * 1994-01-12 2002-04-03 Amersham plc Biological targeting agents
EP0835662B1 (en) * 1996-10-08 2001-11-14 National Institute of Immunology A drug for the treatment of cancer

Also Published As

Publication number Publication date
EP1872800B1 (en) 2012-10-17
EP0831938B1 (en) 2008-05-21
ES2395961T3 (es) 2013-02-18
JP2008266342A (ja) 2008-11-06
JPH11507342A (ja) 1999-06-29
DE69637535D1 (de) 2008-07-03
DK0831938T3 (da) 2008-07-21
EP1872800A2 (en) 2008-01-02
EP1872800A3 (en) 2008-03-19
CA2224153A1 (en) 1996-12-19
CA2224153C (en) 2010-08-17
US5804157A (en) 1998-09-08
JP4236282B2 (ja) 2009-03-11
ATE395938T1 (de) 2008-06-15
ES2308778T3 (es) 2008-12-01
EP0831938A1 (en) 1998-04-01
US5830431A (en) 1998-11-03
EP0831938A4 (en) 2001-12-05
WO1996040291A1 (en) 1996-12-19
PT831938E (pt) 2008-08-26

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