DK1872800T3 - Radiomærkede peptidsammensætninger til stedsspecifik målsøgning - Google Patents
Radiomærkede peptidsammensætninger til stedsspecifik målsøgningInfo
- Publication number
- DK1872800T3 DK1872800T3 DK07019899.9T DK07019899T DK1872800T3 DK 1872800 T3 DK1872800 T3 DK 1872800T3 DK 07019899 T DK07019899 T DK 07019899T DK 1872800 T3 DK1872800 T3 DK 1872800T3
- Authority
- DK
- Denmark
- Prior art keywords
- somatostatin
- peptide
- radiolabeled peptide
- radiolabeled
- diagnostic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/480,373 US5830431A (en) | 1995-06-07 | 1995-06-07 | Radiolabeled peptide compositions for site-specific targeting |
EP96922403A EP0831938B1 (en) | 1995-06-07 | 1996-06-06 | Radiolabeled peptide compositions for site-specific targeting |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1872800T3 true DK1872800T3 (da) | 2013-02-04 |
Family
ID=23907713
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07019899.9T DK1872800T3 (da) | 1995-06-07 | 1996-06-06 | Radiomærkede peptidsammensætninger til stedsspecifik målsøgning |
DK96922403T DK0831938T3 (da) | 1995-06-07 | 1996-06-06 | Radiomærkede peptidsammensætninger til stedspecifik målsögninger |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96922403T DK0831938T3 (da) | 1995-06-07 | 1996-06-06 | Radiomærkede peptidsammensætninger til stedspecifik målsögninger |
Country Status (10)
Country | Link |
---|---|
US (2) | US5830431A (da) |
EP (2) | EP1872800B1 (da) |
JP (2) | JP4236282B2 (da) |
AT (1) | ATE395938T1 (da) |
CA (1) | CA2224153C (da) |
DE (1) | DE69637535D1 (da) |
DK (2) | DK1872800T3 (da) |
ES (2) | ES2395961T3 (da) |
PT (1) | PT831938E (da) |
WO (1) | WO1996040291A1 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5849261A (en) * | 1991-02-08 | 1998-12-15 | Diatide, Inc. | Radiolabeled vasoactive intestinal peptides for diagnosis and therapy |
MY133346A (en) | 1999-03-01 | 2007-11-30 | Biogen Inc | Kit for radiolabeling ligands with yttrium-90 |
US20020102208A1 (en) | 1999-03-01 | 2002-08-01 | Paul Chinn | Radiolabeling kit and binding assay |
US6358491B1 (en) | 1999-08-27 | 2002-03-19 | Berlex Laboratories, Inc. | Somatostatin analogs |
US7067111B1 (en) | 1999-10-25 | 2006-06-27 | Board Of Regents, University Of Texas System | Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging |
JP5448284B2 (ja) * | 2000-06-02 | 2014-03-19 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | エチレンジシステイン(ec)−薬物結合体 |
CA2444483A1 (en) * | 2001-04-26 | 2002-11-07 | Board Of Regents, The University Of Texas System | Diagnostic imaging compositions, their methods of synthesis and use |
US7261875B2 (en) * | 2001-12-21 | 2007-08-28 | Board Of Regents, The University Of Texas System | Dendritic poly (amino acid) carriers and methods of use |
PL377107A1 (pl) * | 2002-11-07 | 2006-01-23 | Board Of Regents, The University Of Texas System | Koniugaty etylenodicysteiny (EC) z lekiem, kompozycje oraz sposoby obrazowania tkankowo specyficznych chorób |
AU2004220104A1 (en) * | 2003-03-10 | 2004-09-23 | Biogen Idec Inc. | Thiol-mediated drug attachment to targeting peptides |
US9050378B2 (en) * | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
EP1861127A1 (en) * | 2005-03-10 | 2007-12-05 | Bayer Schering Pharma Aktiengesellschaft | Chelators for radioactively labeled conjugates comprising a stabilizing sidechain |
US8758723B2 (en) * | 2006-04-19 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for cellular imaging and therapy |
US10925977B2 (en) | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
US9345789B2 (en) | 2009-12-18 | 2016-05-24 | The Board Of Trustees Of The Leland Stanford Junior University | Specific inhibitors and active site probes for legumain |
EP2889295A1 (en) | 2010-08-12 | 2015-07-01 | New York University | Oligooxopiperazines and methods of making and using them |
CN104334541A (zh) | 2012-02-16 | 2015-02-04 | 纽约大学 | 使用低聚氧代哌嗪非肽螺旋模拟物对低氧诱导基因表达的控制 |
JP2015532636A (ja) | 2012-05-08 | 2015-11-12 | リグスホスピタレト | 部位特異的uPAR標的化のための177−Lu標識ペプチド |
SG10201913964QA (en) | 2015-06-25 | 2020-03-30 | Advanced Accelerator Applications | Method of treatment of neuroendocrine tumors that over-express somatostatatin receptors |
PL3568205T3 (pl) | 2017-01-12 | 2024-03-18 | Radiomedix Inc. | Leczenie komórek nowotworowych z nadekspresją receptorów somatostatyny z użyciem pochodnych okreotydu chelatowanych z radioizotopami |
US10596278B2 (en) | 2018-07-25 | 2020-03-24 | Advanced Accelerator Applications (Italy) S.R.L. | Stable, concentrated radionuclide complex solutions |
US10596276B2 (en) | 2018-07-25 | 2020-03-24 | Advanced Accelerator Applications (Italy) S.R.L. | Stable, concentrated radionuclide complex solutions |
US20200085979A1 (en) | 2018-09-11 | 2020-03-19 | Stanley Satz | Precision medicine theranostics and diagnostics a combination thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0029579B1 (en) * | 1979-11-27 | 1983-02-16 | Sandoz Ag | Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use |
US4282143A (en) * | 1980-06-13 | 1981-08-04 | American Home Products Corporation | Octapeptides lowering growth hormone |
US4440904A (en) * | 1983-01-31 | 1984-04-03 | American Home Products Corporation | Nonapeptide anti-secretory agents |
US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
US4585755A (en) * | 1985-04-29 | 1986-04-29 | Merck & Co., Inc. | Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents |
GB9111199D0 (en) * | 1991-05-23 | 1991-07-17 | Sandoz Ltd | Improvements in or relating to organic compounds |
MY106120A (en) * | 1988-12-05 | 1995-03-31 | Novartis Ag | Peptide derivatives. |
US5443816A (en) * | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
JPH04236282A (ja) * | 1991-01-18 | 1992-08-25 | Aica Kogyo Co Ltd | 接着剤組成物 |
EP0600992B1 (en) * | 1991-08-29 | 2000-09-20 | Mallinckrodt Medical, Inc. | Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins |
US5225180A (en) * | 1991-09-10 | 1993-07-06 | Diatech, Inc. | Technetium-99m labeled somatostatin-derived peptides for imaging |
US5411943A (en) * | 1992-02-25 | 1995-05-02 | Biomeasure, Inc. | Hepatoma treatment with somatostatin analogs |
NZ250653A (en) * | 1993-01-12 | 1995-12-21 | Sandoz Ltd | Somatostatin derivatives and pharmaceutical or diagnostic imaging compositions |
US5650134A (en) * | 1993-01-12 | 1997-07-22 | Novartis Ag (Formerly Sandoz Ltd.) | Peptides |
UA44707C2 (uk) * | 1993-08-09 | 2002-03-15 | Біомежер, Інк. | Похідні пептидів та спосіб лікування раку |
EP0730472B1 (en) * | 1993-11-16 | 2006-08-02 | Bracco International B.V. | Immobilized labelling method |
EP0738158B1 (en) * | 1994-01-12 | 2002-04-03 | Amersham plc | Biological targeting agents |
EP0835662B1 (en) * | 1996-10-08 | 2001-11-14 | National Institute of Immunology | A drug for the treatment of cancer |
-
1995
- 1995-06-07 US US08/480,373 patent/US5830431A/en not_active Expired - Lifetime
-
1996
- 1996-06-06 EP EP07019899A patent/EP1872800B1/en not_active Expired - Lifetime
- 1996-06-06 PT PT96922403T patent/PT831938E/pt unknown
- 1996-06-06 ES ES07019899T patent/ES2395961T3/es not_active Expired - Lifetime
- 1996-06-06 EP EP96922403A patent/EP0831938B1/en not_active Expired - Lifetime
- 1996-06-06 JP JP50171497A patent/JP4236282B2/ja not_active Expired - Lifetime
- 1996-06-06 DK DK07019899.9T patent/DK1872800T3/da active
- 1996-06-06 DK DK96922403T patent/DK0831938T3/da active
- 1996-06-06 WO PCT/US1996/009384 patent/WO1996040291A1/en active Application Filing
- 1996-06-06 DE DE69637535T patent/DE69637535D1/de not_active Expired - Lifetime
- 1996-06-06 ES ES96922403T patent/ES2308778T3/es not_active Expired - Lifetime
- 1996-06-06 CA CA2224153A patent/CA2224153C/en not_active Expired - Lifetime
- 1996-06-06 AT AT96922403T patent/ATE395938T1/de active
-
1997
- 1997-12-12 US US08/989,434 patent/US5804157A/en not_active Expired - Lifetime
-
2008
- 2008-05-12 JP JP2008125326A patent/JP2008266342A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1872800B1 (en) | 2012-10-17 |
EP0831938B1 (en) | 2008-05-21 |
ES2395961T3 (es) | 2013-02-18 |
JP2008266342A (ja) | 2008-11-06 |
JPH11507342A (ja) | 1999-06-29 |
DE69637535D1 (de) | 2008-07-03 |
DK0831938T3 (da) | 2008-07-21 |
EP1872800A2 (en) | 2008-01-02 |
EP1872800A3 (en) | 2008-03-19 |
CA2224153A1 (en) | 1996-12-19 |
CA2224153C (en) | 2010-08-17 |
US5804157A (en) | 1998-09-08 |
JP4236282B2 (ja) | 2009-03-11 |
ATE395938T1 (de) | 2008-06-15 |
ES2308778T3 (es) | 2008-12-01 |
EP0831938A1 (en) | 1998-04-01 |
US5830431A (en) | 1998-11-03 |
EP0831938A4 (en) | 2001-12-05 |
WO1996040291A1 (en) | 1996-12-19 |
PT831938E (pt) | 2008-08-26 |
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