DK1872800T3 - Radiomærkede peptidsammensætninger til stedsspecifik målsøgning - Google Patents

Radiomærkede peptidsammensætninger til stedsspecifik målsøgning

Info

Publication number
DK1872800T3
DK1872800T3 DK07019899.9T DK07019899T DK1872800T3 DK 1872800 T3 DK1872800 T3 DK 1872800T3 DK 07019899 T DK07019899 T DK 07019899T DK 1872800 T3 DK1872800 T3 DK 1872800T3
Authority
DK
Denmark
Prior art keywords
somatostatin
peptide
radiolabeled peptide
radiolabeled
diagnostic
Prior art date
Application number
DK07019899.9T
Other languages
English (en)
Inventor
Mary Marmion Dyszlewski
Jack L Erion
Ananthachari Srinivasan
Joseph E Bugaj
Original Assignee
Mallinckrodt Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23907713&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1872800(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mallinckrodt Llc filed Critical Mallinckrodt Llc
Application granted granted Critical
Publication of DK1872800T3 publication Critical patent/DK1872800T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DK07019899.9T 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedsspecifik målsøgning DK1872800T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/480,373 US5830431A (en) 1995-06-07 1995-06-07 Radiolabeled peptide compositions for site-specific targeting
EP96922403A EP0831938B1 (en) 1995-06-07 1996-06-06 Radiolabeled peptide compositions for site-specific targeting

Publications (1)

Publication Number Publication Date
DK1872800T3 true DK1872800T3 (da) 2013-02-04

Family

ID=23907713

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07019899.9T DK1872800T3 (da) 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedsspecifik målsøgning
DK96922403T DK0831938T3 (da) 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedspecifik målsögninger

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK96922403T DK0831938T3 (da) 1995-06-07 1996-06-06 Radiomærkede peptidsammensætninger til stedspecifik målsögninger

Country Status (10)

Country Link
US (2) US5830431A (da)
EP (2) EP0831938B1 (da)
JP (2) JP4236282B2 (da)
AT (1) ATE395938T1 (da)
CA (1) CA2224153C (da)
DE (1) DE69637535D1 (da)
DK (2) DK1872800T3 (da)
ES (2) ES2308778T3 (da)
PT (1) PT831938E (da)
WO (1) WO1996040291A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
MY133346A (en) 1999-03-01 2007-11-30 Biogen Inc Kit for radiolabeling ligands with yttrium-90
US20020102208A1 (en) 1999-03-01 2002-08-01 Paul Chinn Radiolabeling kit and binding assay
US6358491B1 (en) 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
US7067111B1 (en) * 1999-10-25 2006-06-27 Board Of Regents, University Of Texas System Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
DK1286704T3 (da) * 2000-06-02 2014-09-22 Univ Texas Ethylendicystein (EC)-glucose analoge konjugater
US20020197261A1 (en) * 2001-04-26 2002-12-26 Chun Li Therapeutic agent/ligand conjugate compositions, their methods of synthesis and use
US7261875B2 (en) * 2001-12-21 2007-08-28 Board Of Regents, The University Of Texas System Dendritic poly (amino acid) carriers and methods of use
EP1562641A4 (en) * 2002-11-07 2008-12-03 Univ Texas CONJUGATES ETHYLENE DICYSTEINE (EC) -MEDICAMENT, COMPOSITIONS AND METHODS FOR IMAGING TISSUE-SPECIFIC DISEASES
EP1610805A2 (en) * 2003-03-10 2006-01-04 Biogen Idec Inc. Thiol-mediated drug attachment to targeting peptides
US9050378B2 (en) * 2003-12-10 2015-06-09 Board Of Regents, The University Of Texas System N2S2 chelate-targeting ligand conjugates
EP1861127A1 (en) * 2005-03-10 2007-12-05 Bayer Schering Pharma Aktiengesellschaft Chelators for radioactively labeled conjugates comprising a stabilizing sidechain
US8758723B2 (en) * 2006-04-19 2014-06-24 The Board Of Regents Of The University Of Texas System Compositions and methods for cellular imaging and therapy
US10925977B2 (en) * 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
US9345789B2 (en) 2009-12-18 2016-05-24 The Board Of Trustees Of The Leland Stanford Junior University Specific inhibitors and active site probes for legumain
US8791121B2 (en) 2010-08-12 2014-07-29 New York University Oligooxopiperazines and methods of making and using them
EP2814821B1 (en) 2012-02-16 2018-04-25 New York University Control of hypoxia-inducible gene expression with oligooxopiperazine nonpeptidic helix mimetics
JP2015532636A (ja) * 2012-05-08 2015-11-12 リグスホスピタレト 部位特異的ｕＰＡＲ標的化のための１７７−Ｌｕ標識ペプチド
CN108137690A (zh) 2015-06-25 2018-06-08 高级催化剂应用品有限公司 治疗过度表达生长抑素受体的神经内分泌肿瘤的方法
RS64815B1 (sr) 2017-01-12 2023-12-29 Radiomedix Inc Lečenje ćelija kancera koje prekomerno eksprimiraju receptore za somatostatin primenom derivata oktreotida heliranih sa radioizotopima
US10596278B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
US10596276B2 (en) 2018-07-25 2020-03-24 Advanced Accelerator Applications (Italy) S.R.L. Stable, concentrated radionuclide complex solutions
JP2022500464A (ja) 2018-09-11 2022-01-04 サッツ, スタンレイSATZ, Stanley Ｈｅｒ２＋癌および他の新生物の標的放射性核種治療および分子イメージング及び精密治療

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1327A (en) * 1979-11-27 1986-06-27 Sandoz Ag Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use
US4282143A (en) * 1980-06-13 1981-08-04 American Home Products Corporation Octapeptides lowering growth hormone
US4440904A (en) * 1983-01-31 1984-04-03 American Home Products Corporation Nonapeptide anti-secretory agents
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4585755A (en) * 1985-04-29 1986-04-29 Merck & Co., Inc. Cyclic and bridged cyclic somatostatin analogs useful as local anti-inflammatory agents
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
JPH04236282A (ja) * 1991-01-18 1992-08-25 Aica Kogyo Co Ltd 接着剤組成物
JP3853354B2 (ja) * 1991-08-29 2006-12-06 マリンクロッド・インコーポレイテッド 放射性標識ペプチドおよびタンパク質の自己放射線分解を防止する安定剤
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5411943A (en) * 1992-02-25 1995-05-02 Biomeasure, Inc. Hepatoma treatment with somatostatin analogs
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
IL108308A0 (en) * 1993-01-12 1994-04-12 Sandoz Ag Polypeptides, their production and pharmaceutical compositions containing them
ATE284413T1 (de) * 1993-08-09 2004-12-15 Sod Conseils Rech Applic Therapeutische peptid derivate
WO1995013832A1 (en) * 1993-11-16 1995-05-26 Resolution Pharmaceuticals Inc. Immobilized labelling method
WO1995019187A1 (en) * 1994-01-12 1995-07-20 Amersham International Plc Biological targeting agents
EP0835662B1 (en) * 1996-10-08 2001-11-14 National Institute of Immunology A drug for the treatment of cancer

Also Published As

Publication number Publication date
DK0831938T3 (da) 2008-07-21
EP1872800B1 (en) 2012-10-17
WO1996040291A1 (en) 1996-12-19
CA2224153A1 (en) 1996-12-19
US5830431A (en) 1998-11-03
DE69637535D1 (de) 2008-07-03
EP1872800A2 (en) 2008-01-02
US5804157A (en) 1998-09-08
JP2008266342A (ja) 2008-11-06
EP0831938A4 (en) 2001-12-05
PT831938E (pt) 2008-08-26
CA2224153C (en) 2010-08-17
ES2395961T3 (es) 2013-02-18
JP4236282B2 (ja) 2009-03-11
ATE395938T1 (de) 2008-06-15
ES2308778T3 (es) 2008-12-01
JPH11507342A (ja) 1999-06-29
EP1872800A3 (en) 2008-03-19
EP0831938A1 (en) 1998-04-01
EP0831938B1 (en) 2008-05-21

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