PT83187B - Processo para a preparacao de uma formulacao promotora do crescimento capaz de prolongar a libertacao de uma hormona de crescimento, contendo um complexo de metal de transicao de uma hormona de crescimento - Google Patents

Processo para a preparacao de uma formulacao promotora do crescimento capaz de prolongar a libertacao de uma hormona de crescimento, contendo um complexo de metal de transicao de uma hormona de crescimento

Info

Publication number
PT83187B
PT83187B PT83187A PT8318786A PT83187B PT 83187 B PT83187 B PT 83187B PT 83187 A PT83187 A PT 83187A PT 8318786 A PT8318786 A PT 8318786A PT 83187 B PT83187 B PT 83187B
Authority
PT
Portugal
Prior art keywords
growth hormone
growth
liberation
prolonging
preparing
Prior art date
Application number
PT83187A
Other languages
English (en)
Other versions
PT83187A (en
Inventor
Jerome L Martin
John F Kraemer
Original Assignee
Int Minerals & Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Minerals & Chem Corp filed Critical Int Minerals & Chem Corp
Publication of PT83187A publication Critical patent/PT83187A/pt
Publication of PT83187B publication Critical patent/PT83187B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PT83187A 1985-08-12 1986-08-12 Processo para a preparacao de uma formulacao promotora do crescimento capaz de prolongar a libertacao de uma hormona de crescimento, contendo um complexo de metal de transicao de uma hormona de crescimento PT83187B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76440085A 1985-08-12 1985-08-12

Publications (2)

Publication Number Publication Date
PT83187A PT83187A (en) 1986-09-01
PT83187B true PT83187B (pt) 1988-07-01

Family

ID=25070628

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83187A PT83187B (pt) 1985-08-12 1986-08-12 Processo para a preparacao de uma formulacao promotora do crescimento capaz de prolongar a libertacao de uma hormona de crescimento, contendo um complexo de metal de transicao de uma hormona de crescimento

Country Status (12)

Country Link
EP (1) EP0216485A1 (pt)
JP (1) JPS6248635A (pt)
KR (1) KR870001825A (pt)
CN (1) CN86105023A (pt)
AU (1) AU596112B2 (pt)
BR (1) BR8603848A (pt)
DK (1) DK384286A (pt)
ES (1) ES2000864A6 (pt)
IL (1) IL79681A (pt)
NZ (1) NZ217175A (pt)
PT (1) PT83187B (pt)
ZA (1) ZA866052B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE62598T1 (de) * 1984-10-04 1991-05-15 Monsanto Co Verzoegerte freisetzung biologisch aktiver somatotropine.
IL79765A (en) * 1985-08-23 1992-02-16 Lilly Co Eli Injectable sustained release formulations of bovine somatotropin
CA1257199A (en) * 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo
EP0277043A3 (en) * 1987-01-30 1989-08-23 IMCERA Group Inc. Method for recovering somatotropins from dilute aqueous solution
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
US5122512A (en) * 1988-09-12 1992-06-16 Pitman-Moore, Inc. Swine growth promoting composition
AU653325B2 (en) * 1990-02-12 1994-09-29 Lucky Limited A composition durably releasing bioactive polypeptides
US5780599A (en) * 1990-07-13 1998-07-14 Novo Nordisk A/S Growth hormone crystals and a process for production of growth hormone crystals
US6894023B1 (en) 1990-07-13 2005-05-17 Novo Nordisk A/S Growth hormone crystals and a process for production of these GH-crystals
DK168790D0 (pt) * 1990-07-13 1990-07-13 Novo Nordisk As
AU1757092A (en) * 1991-03-28 1992-11-02 Genentech Inc. Stable growth hormone metal ion formulations
YU87892A (sh) * 1991-10-01 1995-12-04 Eli Lilly And Company Lilly Corporate Center Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu
US6022858A (en) * 1991-12-20 2000-02-08 Novo Nordisk A/S Pharmaceutical formulation of human-growth hormone pretreated with zinc salt
US6087324A (en) * 1993-06-24 2000-07-11 Takeda Chemical Industries, Ltd. Sustained-release preparation
SE9303068D0 (sv) * 1993-09-21 1993-09-21 Kabi Pharmacia Ab New use
PT779806E (pt) * 1994-09-09 2001-02-28 Takeda Chemical Industries Ltd Preparacao de libertacao sustentada contendo um sal metalico de um peptido
ATE268591T1 (de) 1995-06-27 2004-06-15 Takeda Chemical Industries Ltd Verfahren zur herstellung von zubereitungen mit verzögerter freisetzung
US6191107B1 (en) * 1997-09-26 2001-02-20 Takeda Chemical Industries, Ltd. Complex of human growth hormone and zinc
US6451347B1 (en) * 1999-03-01 2002-09-17 Alkermes Controlled Therapeutics, Inc. Method for purifying human growth hormone
KR100890679B1 (ko) 2000-02-24 2009-03-26 일라이 릴리 앤드 캄파니 소마토트로핀의 지속적인 방출을 위한 비수성 주사제제들
JP4361710B2 (ja) * 2000-04-19 2009-11-11 ジェネンテック・インコーポレーテッド 徐放製剤
AU2001271491A1 (en) 2000-06-26 2002-01-08 Monsanto Technology Llc Non-aqueous surfactant-containing formulations for extended release of somatotropin
US6664234B1 (en) 2000-06-30 2003-12-16 Monsanto Technology Llc Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin
WO2002011695A2 (en) 2000-08-07 2002-02-14 Inhale Therapeutic Systems, Inc. Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
WO2002067991A1 (en) 2001-02-23 2002-09-06 Genentech, Inc. Erodible polymers for injection
EP1397155B1 (en) * 2001-06-21 2015-09-30 Genentech, Inc. Sustained release formulation
BR0317888A (pt) 2002-12-31 2005-12-06 Altus Pharmaceuticals Inc Cristais do hormÈnio do crescimento humano e processos para preparação dos mesmos
WO2004060920A1 (en) * 2002-12-31 2004-07-22 Altus Pharmaceuticals Inc. Complexes of protein crystals and ionic polymers
CA2784793A1 (en) 2009-12-21 2011-07-21 Ambrx, Inc. Modified bovine somatotropin polypeptides and their uses
NZ600363A (en) 2009-12-21 2014-07-25 Ambrx Inc Modified porcine somatotropin polypeptides and their uses
US20160303242A1 (en) 2013-12-09 2016-10-20 Durect Corporation Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB885798A (en) * 1958-12-06 1961-12-28 Organon Labor Ltd Preparations of the growth hormone
DK100792C (da) * 1961-05-23 1965-01-18 Dumex Ltd As Fremgangsmåde til fremstilling af et præparat med protraheret vitamin B12-virkning.
DE2158123A1 (de) * 1970-12-02 1972-06-08 Ciba-Geigy Ag, Basel (Schweiz) Neue pharmazeutische Präparate
US4333919A (en) * 1979-09-12 1982-06-08 Eli Lilly And Company Growth promotant controlled release formulations and method of treatment

Also Published As

Publication number Publication date
CN86105023A (zh) 1988-02-24
JPS6248635A (ja) 1987-03-03
AU596112B2 (en) 1990-04-26
PT83187A (en) 1986-09-01
AU6109286A (en) 1987-02-19
DK384286D0 (da) 1986-08-12
IL79681A0 (en) 1986-11-30
ZA866052B (en) 1987-03-25
DK384286A (da) 1987-02-13
KR870001825A (ko) 1987-03-28
EP0216485A1 (en) 1987-04-01
ES2000864A6 (es) 1988-03-16
IL79681A (en) 1991-06-10
NZ217175A (en) 1989-11-28
BR8603848A (pt) 1987-03-24

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Effective date: 19930630