PT83877B - Processo para a preparacao de uma composicao de dextrometorfano de libertacao prolongada contendo um resinato - Google Patents

Processo para a preparacao de uma composicao de dextrometorfano de libertacao prolongada contendo um resinato

Info

Publication number
PT83877B
PT83877B PT83877A PT8387786A PT83877B PT 83877 B PT83877 B PT 83877B PT 83877 A PT83877 A PT 83877A PT 8387786 A PT8387786 A PT 8387786A PT 83877 B PT83877 B PT 83877B
Authority
PT
Portugal
Prior art keywords
dextrometorphanic
preparing
resin
composition containing
prolonged liberation
Prior art date
Application number
PT83877A
Other languages
English (en)
Other versions
PT83877A (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of PT83877A publication Critical patent/PT83877A/pt
Publication of PT83877B publication Critical patent/PT83877B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT83877A 1985-12-09 1986-12-05 Processo para a preparacao de uma composicao de dextrometorfano de libertacao prolongada contendo um resinato PT83877B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/806,879 US4788055A (en) 1985-12-09 1985-12-09 Resinate sustained release dextromethorphan composition

Publications (2)

Publication Number Publication Date
PT83877A PT83877A (en) 1987-01-01
PT83877B true PT83877B (pt) 1989-06-30

Family

ID=25195036

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83877A PT83877B (pt) 1985-12-09 1986-12-05 Processo para a preparacao de uma composicao de dextrometorfano de libertacao prolongada contendo um resinato

Country Status (10)

Country Link
US (1) US4788055A (pt)
EP (1) EP0225615A3 (pt)
JP (1) JPS62138428A (pt)
AU (1) AU597316B2 (pt)
DK (1) DK160601C (pt)
FI (1) FI87525C (pt)
IE (1) IE863209L (pt)
NO (1) NO864918L (pt)
PT (1) PT83877B (pt)
ZA (1) ZA869255B (pt)

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US5219563A (en) * 1988-05-11 1993-06-15 Glaxo Group Limited Drug adsorbates
IL90245A (en) * 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it
IT1226800B (it) * 1988-09-16 1991-02-19 Prodotti Formenti Composizioni farmaceutiche orali contenenti sali di destrorfano.
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
CA2002492A1 (en) * 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5840293A (en) * 1988-11-16 1998-11-24 Advanced Polymer Systems, Inc. Ionic beads for controlled release and adsorption
GB9005498D0 (en) * 1990-03-12 1990-05-09 Beecham Group Plc Composition
JP3286315B2 (ja) * 1990-06-20 2002-05-27 アドバンスト ポリマー システムズ，インコーポレイティド 可溶性活性物質の調節された放出のための組成物及び方法
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
CA2128296A1 (en) * 1993-12-22 1995-06-23 Peter John Degen Polyvinylidene fluoride membrane
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
AU736308B2 (en) * 1996-12-20 2001-07-26 Warner-Lambert Company Llc Antitussive drugs delivered by ion exchange resins
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
PT1200129E (pt) * 1999-07-14 2008-12-17 Schering Plough Ltd Máscara de sabor para preparações orais líquidas de quinolona com utilização de resinas de permuta iónica
US6514492B1 (en) 1999-07-14 2003-02-04 Schering-Plough Veterinary Corporation Taste masking of oral quinolone liquid preparations using ion exchange resins
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
ATE318299T1 (de) * 2000-06-09 2006-03-15 Procter & Gamble Verfahren zur behandlung von gewebe mit einem waschmittelformkörper enthaltend ein ionenaustauscherharz
US6855721B1 (en) 2000-07-28 2005-02-15 Indevus Pharmaceuticals, Inc. Methods and compositions for alleviating stuttering
US20030099711A1 (en) * 2001-08-29 2003-05-29 David Meadows Sustained release preparations
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US20030180249A1 (en) * 2002-03-18 2003-09-25 Khanna Satish Chandra Dosage forms for hygroscopic active ingredients
US8906413B2 (en) 2003-05-12 2014-12-09 Supernus Pharmaceuticals, Inc. Drug formulations having reduced abuse potential
US20050142097A1 (en) * 2003-12-29 2005-06-30 Deepak Thassu Multiple active drug resin conjugate
US20050238695A1 (en) * 2004-04-27 2005-10-27 Atma Chaudhari Lozenge for delivery of dextromethorphan
CN101014331A (zh) * 2004-04-27 2007-08-08 美迪诺亚公司 苯氧烷羧酸衍生物在治疗炎症中的应用
WO2005110412A1 (en) * 2004-05-14 2005-11-24 Green Cross Corp. Neuroprotective properties of dextrorotatory morphinans
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
WO2006044805A2 (en) * 2004-10-15 2006-04-27 Supernus Pharmaceuticals, Inc. Less abusable pharmaceutical preparations
EP1898913A1 (en) * 2005-06-28 2008-03-19 Ucb, S.A. Multiple active drug-resin conjugate
AU2006292946B2 (en) * 2005-09-21 2009-12-10 Chong Kun Dang Pharmaceutical Corp. Novel resinate complex of s-clopidogrel and production method thereof
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
EP2813144A1 (en) 2006-10-09 2014-12-17 Charleston Laboratories, Inc. Analgesic compositions comprising an antihistamine
MX2009005339A (es) * 2006-11-21 2009-06-01 Mcneil Ppc Inc Suspensiones analgesicas de liberacion modificada.
US9833510B2 (en) 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
EP3090743A1 (en) 2008-01-09 2016-11-09 Charleston Laboratories, Inc. Pharmaceutical compositions for treating headache and eliminating nausea
US20100273822A1 (en) * 2009-04-22 2010-10-28 William Wayne Howard Immediate release compositions and methods for delivering drug formulations using strong acid ion exchange resins
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
CN102138915A (zh) * 2011-03-28 2011-08-03 于晓勇 一种口服药物制剂及其制备方法
WO2013070656A1 (en) * 2011-11-07 2013-05-16 Navinta Llc Sustained release suspension preparation for dextromethorphan
US8962687B2 (en) 2012-12-05 2015-02-24 Medicinova, Inc. Method of treating liver disorders
JP2013119550A (ja) 2011-12-08 2013-06-17 Medicinova Inc 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
KR102352728B1 (ko) 2013-07-25 2022-01-18 메디시노바, 인크. 트리글리세라이드, 총 콜레스테롤, 및 저밀도 지단백질의 혈중농도를 감소시키는 방법
US9346754B2 (en) 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
US20150321989A1 (en) 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
US9498458B2 (en) 2014-06-02 2016-11-22 Medicinova, Inc. Method of inhibiting or treating fibrosis
KR102462638B1 (ko) 2014-11-26 2022-11-03 메디시노바, 인크. 이부딜라스트와 릴루졸의 배합물 및 이의 사용방법
US11103499B2 (en) 2016-08-26 2021-08-31 EXCIVA (UG) (haftungsbeschränkt) Compositions and methods thereof
US10745540B2 (en) * 2017-08-01 2020-08-18 Carefusion 2200, Inc. Protection and selective release of colorant
EP4346783A1 (en) 2021-05-28 2024-04-10 MediciNova, Inc. Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels

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FR1413851A (fr) * 1957-05-06 1965-10-15 Clinical Products Ltd Procédé de fabrication de composés destinés à dégager lentement et uniformément une substance active dans un milieu soit acide, soit basique
US2990332A (en) * 1958-04-02 1961-06-27 Wallace & Tiernan Inc Pharmaceutical preparations comprising cation exchange resin adsorption compounds and treatment therewith
US3085942A (en) * 1960-12-28 1963-04-16 Hoffmann La Roche Antitussive compositions and preparation
FR7759M (pt) * 1967-10-31 1970-03-16
GB1348642A (en) * 1970-10-15 1974-03-20 Howard A N Hypocholesterolaemic compositions
US4221778A (en) * 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
US4427681A (en) * 1982-09-16 1984-01-24 Richardson-Vicks, Inc. Thixotropic compositions easily convertible to pourable liquids
US4694010A (en) * 1985-08-16 1987-09-15 New York University Anticonvulsant compositions and method

Also Published As

Publication number Publication date
ZA869255B (en) 1987-07-29
FI864975L (fi) 1987-06-10
US4788055A (en) 1988-11-29
EP0225615A3 (en) 1988-04-20
EP0225615A2 (en) 1987-06-16
FI87525B (fi) 1992-10-15
NO864918L (no) 1987-06-10
DK160601C (da) 1991-09-02
PT83877A (en) 1987-01-01
AU6618186A (en) 1987-06-11
FI864975A0 (fi) 1986-12-05
NO864918D0 (no) 1986-12-08
IE863209L (en) 1987-06-09
DK589086A (da) 1987-06-10
AU597316B2 (en) 1990-05-31
FI87525C (fi) 1993-01-25
DK160601B (da) 1991-04-02
DK589086D0 (da) 1986-12-08
JPS62138428A (ja) 1987-06-22

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Effective date: 19940630