PT83096B - Processo para a preparacao de vacinas conjugadas contendo polissacaridos e proteinas contra infeccoes provocadas por bacterias gram-negativas - Google Patents

Processo para a preparacao de vacinas conjugadas contendo polissacaridos e proteinas contra infeccoes provocadas por bacterias gram-negativas

Info

Publication number
PT83096B
PT83096B PT83096A PT8309686A PT83096B PT 83096 B PT83096 B PT 83096B PT 83096 A PT83096 A PT 83096A PT 8309686 A PT8309686 A PT 8309686A PT 83096 B PT83096 B PT 83096B
Authority
PT
Portugal
Prior art keywords
toxin
polysaccharide
polysacarides
gram
preparation
Prior art date
Application number
PT83096A
Other languages
English (en)
Other versions
PT83096A (en
Inventor
Stanley Cryz
Emil Fuerer
Original Assignee
Schweizererisches Serum Impfin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schweizererisches Serum Impfin filed Critical Schweizererisches Serum Impfin
Publication of PT83096A publication Critical patent/PT83096A/pt
Publication of PT83096B publication Critical patent/PT83096B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PT83096A 1985-09-27 1986-07-29 Processo para a preparacao de vacinas conjugadas contendo polissacaridos e proteinas contra infeccoes provocadas por bacterias gram-negativas PT83096B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH419985 1985-09-27

Publications (2)

Publication Number Publication Date
PT83096A PT83096A (en) 1986-08-01
PT83096B true PT83096B (pt) 1988-07-01

Family

ID=4271640

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83096A PT83096B (pt) 1985-09-27 1986-07-29 Processo para a preparacao de vacinas conjugadas contendo polissacaridos e proteinas contra infeccoes provocadas por bacterias gram-negativas

Country Status (11)

Country Link
US (1) US4771127A (pt)
EP (1) EP0220387B1 (pt)
JP (1) JPH0662434B2 (pt)
AT (1) ATE56615T1 (pt)
AU (1) AU587865B2 (pt)
CA (1) CA1276552C (pt)
DE (1) DE3674328D1 (pt)
DK (1) DK163176C (pt)
ES (1) ES2000140A6 (pt)
PT (1) PT83096B (pt)
ZA (1) ZA866564B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360897A (en) * 1981-08-31 1994-11-01 The University Of Rochester Immunogenic conjugates of streptococcus pneumonial capsular polymer and toxin or in toxiad
US5057301A (en) * 1988-04-06 1991-10-15 Neorx Corporation Modified cellular substrates used as linkers for increased cell retention of diagnostic and therapeutic agents
JP2639416B2 (ja) * 1988-04-23 1997-08-13 財団法人化学及血清療法研究所 真珠生産用二枚貝の血球活性化製剤および該製剤を用いる真珠の生産方法
NZ239643A (en) * 1990-09-17 1996-05-28 North American Vaccine Inc Vaccine containing bacterial polysaccharide protein conjugate and adjuvant (c-nd-che-a-co-b-r) with a long chain alkyl group.
US6139843A (en) * 1991-04-02 2000-10-31 Albert Einstein College Of Medicine Of Yeshiva University Peptide compositions for the treatment of HIV
US5370872A (en) * 1991-08-12 1994-12-06 Swiss Serum And Vaccine Institute Berne Escherichia coliO-polysaccharide-protein conjugate vaccine
US5554730A (en) * 1993-03-09 1996-09-10 Middlesex Sciences, Inc. Method and kit for making a polysaccharide-protein conjugate
US5866132A (en) * 1995-06-07 1999-02-02 Alberta Research Council Immunogenic oligosaccharide compositions
US5695768A (en) * 1995-06-07 1997-12-09 Alberta Research Council Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides
US6749831B1 (en) * 1997-05-16 2004-06-15 Medical Defense Technology, Llc Vaccine against lipopolysaccharide core
MXPA00003108A (es) * 1997-10-03 2001-07-01 Polisacaridos formadores de iminas, preparacion de los mismos y el uso como adyuvantes e inmunoestimulan
EP1073667A2 (en) 1998-04-28 2001-02-07 Galenica Pharmaceuticals, Inc. Polysaccharide-antigen conjugates
JP2004515450A (ja) * 2000-04-18 2004-05-27 エンドバイオロジックス, インコーポレイテッド 敗血症処置のためのリポ多糖結合体ワクチン
US7749511B2 (en) * 2000-04-18 2010-07-06 Endobiologics, Incorporated Anti-sepsis conjugate vaccine
US8048432B2 (en) 2003-08-06 2011-11-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Polysaccharide-protein conjugate vaccines
CA2844154C (en) * 2003-08-06 2016-12-20 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polysaccharide-protein conjugate vaccines
US7625736B2 (en) * 2004-06-04 2009-12-01 The United States Of America As Represented By The Department Of Health And Human Services Methods for preparing immunogenic conjugates
WO2005117965A1 (en) * 2004-06-04 2005-12-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for preparing immunogenic conjugates
JP5382380B2 (ja) * 2008-10-21 2014-01-08 インターナショナル ワクチン インスティテュート 新規のシゲラタンパク質抗原及び方法
CN101912609B (zh) * 2009-08-20 2012-02-01 成都蓉生药业有限责任公司 防治绿脓杆菌感染的组合物及其制备方法
CA2871081A1 (en) 2011-04-21 2012-10-26 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Peptide and conjugate vaccines for fungal infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4356170A (en) * 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4619828A (en) * 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
US4663160A (en) * 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4693891A (en) * 1985-09-09 1987-09-15 Miles Laboratories, Inc. Vaccine for Pseudomonas aeruginosa
US4707543A (en) * 1985-09-17 1987-11-17 The United States Of America As Represented By The Secretary Of The Army Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines

Also Published As

Publication number Publication date
DK163176B (da) 1992-02-03
DK163176C (da) 1992-06-22
DE3674328D1 (de) 1990-10-25
ZA866564B (en) 1987-05-27
DK320786D0 (da) 1986-07-04
EP0220387A3 (en) 1989-03-22
DK320786A (da) 1987-03-28
EP0220387B1 (de) 1990-09-19
JPH0662434B2 (ja) 1994-08-17
AU6322986A (en) 1987-04-02
AU587865B2 (en) 1989-08-31
PT83096A (en) 1986-08-01
ES2000140A6 (es) 1987-12-16
CA1276552C (en) 1990-11-20
US4771127A (en) 1988-09-13
EP0220387A2 (de) 1987-05-06
ATE56615T1 (de) 1990-10-15
JPS6289632A (ja) 1987-04-24

Similar Documents

Publication Publication Date Title
PT83096B (pt) Processo para a preparacao de vacinas conjugadas contendo polissacaridos e proteinas contra infeccoes provocadas por bacterias gram-negativas
CA1336308C (en) Polysaccharide-protein conjugates
EP0598818B1 (en) Escherichia coli o-polysaccharide-protein conjugate vaccine
Knirel Polysaccharide antigens of Pseudomonas aeruginosa
AU601742B2 (en) Immunogenic conjugates
CA1181344A (en) Immunogenic polysaccharide-protein conjugates
Cryz et al. Safety and immunogenicity of a Pseudomonas aeruginosa O-polysaccharide toxin A conjugate vaccine in humans.
KR920003982A (ko) 면역원성 콘쥬게이트 및 이를 함유하는 백신 조성물
CA2246760C (en) Polysaccharide-peptide-conjugates
FI110164B (fi) Menetelmä oligosakkaridin valmistamiseksi depolymeroimalla antigeeninen polysakkaridi
US20040213804A1 (en) Immunogenic beta-propionamido-linked polysaccharide protein conjugate useful as a vaccine produced using an N-acryloylated polysaccharide
Seid et al. Preparation and characterization of detoxified lipopolysaccharide-protein conjugates.
AU740784B2 (en) Coupling of unmodified proteins to haloacyl or dihaloacyl derivatized polysaccharides for the preparation of protein-polysaccharide vaccines
US20060134141A1 (en) Glycoconjugate vaccines containing peptidoglycan
CA2145397A1 (en) Group b streptococcus type ii and type v polysaccharide-protein conjugate vaccines
Midwinter et al. Vaccination of mice with lipopolysaccharide (LPS) and LPS-derived immuno-conjugates from Leptospira interrogans
Khatuntseva et al. Cross reacting material (CRM197) as a carrier protein for carbohydrate conjugate vaccines targeted at bacterial and fungal pathogens
AU678549B2 (en) Detoxified LPS-cholera toxin conjugate vaccine for prevention of cholera
US6165468A (en) Antigenic carbohydrate linked to an immunogenic carrier
Tsay et al. Preparation and characterization of a nontoxic polysaccharide-protein conjugate that induces active immunity and passively protective antibody against Pseudomonas aeruginosa immunotype 1 in mice
Singh et al. Protective efficacy and immunogenicity of Vi-porin conjugate against Salmonella typhi
Muniandy et al. Immunogenicity of purified lipopolysaccharide or protein–oligosaccharide conjugates of Pasteurella multocida type 6: B in mice
Chhibber et al. Immunoprotective potential of polysaccharide-tetanus toxoid conjugate in Klebsiella pneumoniae induced lobar pneumonia in rats
Tiwari et al. Immunobiology of lipopolysaccharide (LPS) and LPS-derived immunoconjugates vaccinate mice against Salmonella typhimurium
US20210401960A1 (en) Multivalent glycoconjugates immunogenic compositions

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Effective date: 20050623