PT81605A - Imidazolylalkylguanidinderivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Imidazolylalkylguanidinderivate verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
PT81605A
PT81605A PT81605A PT8160585A PT81605A PT 81605 A PT81605 A PT 81605A PT 81605 A PT81605 A PT 81605A PT 8160585 A PT8160585 A PT 8160585A PT 81605 A PT81605 A PT 81605A
Authority
PT
Portugal
Prior art keywords
imidazolylalkylguanidine
compounds
manufacture
medicaments containing
derivatives process
Prior art date
Application number
PT81605A
Other languages
German (de)
English (en)
Other versions
PT81605B (pt
Original Assignee
Heumann Pharma Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853512084 external-priority patent/DE3512084A1/de
Priority claimed from DE19853528214 external-priority patent/DE3528214A1/de
Priority claimed from DE19853528215 external-priority patent/DE3528215A1/de
Application filed by Heumann Pharma Gmbh & Co filed Critical Heumann Pharma Gmbh & Co
Publication of PT81605A publication Critical patent/PT81605A/pt
Publication of PT81605B publication Critical patent/PT81605B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
PT81605A 1985-04-02 1985-12-04 Processo para a preparacao de derivados de imidazolilalquil-guanidina e de composicoes farmaceuticas contendo estes compostos PT81605B (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19853512084 DE3512084A1 (de) 1985-04-02 1985-04-02 Guanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE19853528214 DE3528214A1 (de) 1985-08-06 1985-08-06 Arylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE19853528215 DE3528215A1 (de) 1985-08-06 1985-08-06 Heteroarylalkylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
PT81605A true PT81605A (de) 1986-01-01
PT81605B PT81605B (pt) 1987-10-20

Family

ID=27192965

Family Applications (1)

Application Number Title Priority Date Filing Date
PT81605A PT81605B (pt) 1985-04-02 1985-12-04 Processo para a preparacao de derivados de imidazolilalquil-guanidina e de composicoes farmaceuticas contendo estes compostos

Country Status (13)

Country Link
US (1) US5021431A (pt)
EP (1) EP0199845B1 (pt)
KR (1) KR930011491B1 (pt)
AU (1) AU589586B2 (pt)
CA (1) CA1266657A (pt)
DE (1) DE3579000D1 (pt)
DK (1) DK165367C (pt)
ES (4) ES8802042A1 (pt)
GR (1) GR852852B (pt)
HU (1) HU198024B (pt)
IE (1) IE58777B1 (pt)
PT (1) PT81605B (pt)
YU (2) YU45929B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631334A1 (de) * 1986-09-15 1988-03-17 Heumann Pharma Gmbh & Co Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726381A1 (de) * 1987-08-07 1989-02-16 Heumann Pharma Gmbh & Co Guanidincarbonsaeureester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE120461T1 (de) * 1990-01-15 1995-04-15 Heumann Pharma Gmbh & Co Imidazolylpropylguanidinderivat, verfahren zu seiner herstellung und diese verbindung enthaltende arzneimittel.
ATE109979T1 (de) * 1990-03-30 1994-09-15 Heumann Pharma Gmbh & Co Verwendung von guanidinderivaten zur herstellung eines arzneimittels mit npy-antagonistischer wirkung.
ES2108107T3 (es) * 1991-02-27 1997-12-16 Seed Capital Investments Derivados de imidazol que tienen actividad antagonista en el receptor h3 de histamina.
DE4119696A1 (de) * 1991-06-14 1992-12-17 Edmund Dr Neugebauer Verwendung von guanidinderivaten zur herstellung eines arzneimittels zur behandlung des sepsis-syndroms, des sepsis-like syndroms und des septischen schocks
FR2686084B1 (fr) * 1992-01-10 1995-12-22 Bioprojet Soc Civ Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques.
USRE37303E1 (en) * 1992-01-10 2001-07-31 Institut National Del La Sante Et De La Recherche Medicale Imidazole compounds and their therapeutic applications
CA2237384A1 (en) * 1995-11-13 1997-05-22 The Albany Medical College Analgesic compounds and uses thereof
EP0912551A1 (en) * 1996-05-14 1999-05-06 Novo Nordisk A/S Somatostatin agonists and antagonists
US6127343A (en) * 1996-05-14 2000-10-03 Novo Nordisk A/S Somatostatin agonists and antagonists
AU4772497A (en) * 1996-10-31 1998-05-22 Novo Nordisk A/S Constrained somatostatin agonists and antagonists
DE19755016A1 (de) 1997-12-11 1999-06-17 Bayer Ag Substituierte 2,4-Diamino-1,3,5-triazine
GB9803536D0 (en) 1998-02-19 1998-04-15 Black James Foundation Histamine H,receptor ligands
US6232316B1 (en) 1998-06-16 2001-05-15 Targacept, Inc. Methods for treatment of CNS disorders

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
US4048319A (en) * 1969-10-29 1977-09-13 Smith Kline & French Laboratories Limited Method of inhibiting histamine activity with quanidine compounds
GB1431589A (en) 1973-07-13 1976-04-07 Smith Kline French Lab Ureas, thioureas and guanidines n,n-disubstituted by heterocyclo- alkylene and/or heterocycloalkylenethioalkylene groups
US4070472A (en) * 1974-02-07 1978-01-24 Smith Kline & French Laboratories Limited Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine
US4107319A (en) * 1974-03-12 1978-08-15 Smith Kline & French Laboratories Limited Pharmacologically active compounds
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
GB1602458A (en) * 1977-05-05 1981-11-11 Smith Kline French Lab Bisamidines as histamine h2-antagonists
DK221081A (da) * 1980-05-31 1981-12-01 Smith Kline French Lab Fremgangsmaade til fremstilling af heterocyklylalkylanidiner mellemprodukter til anvendelse ved denne fremgangsmaade og en fremgangsmaade til fremstilling af disse mellemprodukter
DE3631334A1 (de) * 1986-09-15 1988-03-17 Heumann Pharma Gmbh & Co Neue imidazolylguanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
KR930011491B1 (ko) 1993-12-08
ES557692A0 (es) 1988-03-01
AU589586B2 (en) 1989-10-19
ES8802042A1 (es) 1988-04-01
DK538885D0 (da) 1985-11-21
EP0199845B1 (de) 1990-08-01
YU45469B (en) 1992-05-28
HU198024B (en) 1989-07-28
KR860008147A (ko) 1986-11-12
IE853319L (en) 1986-10-02
PT81605B (pt) 1987-10-20
IE58777B1 (en) 1993-11-17
US5021431A (en) 1991-06-04
ES550875A0 (es) 1988-04-01
DE3579000D1 (de) 1990-09-06
GR852852B (pt) 1986-08-11
YU45929B (sh) 1992-09-07
ES8801820A1 (es) 1988-03-01
AU5182886A (en) 1986-10-09
ES557693A0 (es) 1988-03-01
DK165367B (da) 1992-11-16
EP0199845A1 (de) 1986-11-05
ES557691A0 (es) 1988-03-01
HUT41392A (en) 1987-04-28
ES8801819A1 (es) 1988-03-01
CA1266657A (en) 1990-03-13
DK165367C (da) 1993-04-05
DK538885A (da) 1986-10-03
YU210187A (en) 1988-10-31
ES8801821A1 (es) 1988-03-01
YU207285A (en) 1988-06-30

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960930