PT78496A - Process for the preparation of ergoline derivatives - Google Patents

Process for the preparation of ergoline derivatives

Info

Publication number
PT78496A
PT78496A PT78496A PT7849684A PT78496A PT 78496 A PT78496 A PT 78496A PT 78496 A PT78496 A PT 78496A PT 7849684 A PT7849684 A PT 7849684A PT 78496 A PT78496 A PT 78496A
Authority
PT
Portugal
Prior art keywords
preparation
ergoline derivatives
ergoline
derivatives
Prior art date
Application number
PT78496A
Other languages
English (en)
Other versions
PT78496B (en
Inventor
Luigi Bernardi
Laura Chiodini
Sergio Mantegani
Daniela Ruggieri
Aldemio Temperilli
Patricia Salvati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311679A external-priority patent/GB8311679D0/en
Priority claimed from GB838314816A external-priority patent/GB8314816D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of PT78496A publication Critical patent/PT78496A/pt
Publication of PT78496B publication Critical patent/PT78496B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT78496A 1983-04-28 1984-04-26 Process for the preparation of ergoline derivatives PT78496B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838311679A GB8311679D0 (en) 1983-04-28 1983-04-28 Ergoline derivatives
GB838314816A GB8314816D0 (en) 1983-05-27 1983-05-27 Ergoline derivatives

Publications (2)

Publication Number Publication Date
PT78496A true PT78496A (en) 1984-05-01
PT78496B PT78496B (en) 1986-07-22

Family

ID=26285978

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78496A PT78496B (en) 1983-04-28 1984-04-26 Process for the preparation of ergoline derivatives

Country Status (18)

Country Link
US (1) US4690929A (pt)
EP (1) EP0126968B1 (pt)
KR (1) KR900008696B1 (pt)
AU (1) AU556968B2 (pt)
CA (1) CA1205801A (pt)
DE (1) DE3475709D1 (pt)
DK (1) DK162996C (pt)
ES (1) ES8506031A1 (pt)
FI (1) FI81349C (pt)
GR (1) GR79575B (pt)
HU (1) HU198713B (pt)
IE (1) IE57240B1 (pt)
IL (1) IL71633A (pt)
NO (1) NO161562C (pt)
PH (1) PH21123A (pt)
PT (1) PT78496B (pt)
SU (1) SU1327788A3 (pt)
YU (1) YU43357B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
NL8400333A (nl) * 1983-02-16 1984-09-17 Sandoz Ag Moederkoornalkaloiden, hun bereiding en hun toepassing.
GB8501078D0 (en) * 1985-01-16 1985-02-20 Erba Farmitalia Piperazin-1-yl-ergo-line derivatives
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8515528D0 (en) * 1985-06-19 1985-07-24 Erba Farmitalia Ergoline derivatives
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3528576A1 (de) * 1985-08-06 1987-02-19 Schering Ag Verfahren zur herstellung von ergolin-thioharnstoffen
DE3535929A1 (de) * 1985-10-04 1987-04-09 Schering Ag 1,2-disubstituierte ergolinderivate
GB8617907D0 (en) * 1986-07-22 1986-08-28 Erba Farmitalia Tetracyclic indole derivatives
GB8702364D0 (en) * 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
ES2083564T3 (es) * 1990-01-25 1996-04-16 Pharmacia Spa Procedimiento para la preparacion de derivados de ergolina.
GB9006772D0 (en) * 1990-03-27 1990-05-23 Erba Carlo Spa 4-piperidinyl-ergoline derivatives
TW252979B (pt) * 1992-12-24 1995-08-01 Erba Carlo Spa
KR100743212B1 (ko) 2001-06-08 2007-07-26 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. 소마토스타틴-도파민 키메라 유사체
US9777039B2 (en) 2012-11-01 2017-10-03 Ipsen Pharma S.A.S. Somatostatin analogs and dimers thereof
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL283102A (pt) * 1961-09-11
SE393615B (sv) * 1971-05-19 1977-05-16 Sandoz Ag Forfarande for framstellning av 6-metyl-8 beta-ureidometyl-ergolener
NL7416120A (nl) * 1973-12-21 1975-06-24 Farmaceutici Italia Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten.
US3996228A (en) * 1973-12-21 1976-12-07 Societa' Farmaceutici Italia S.P.A. Pyrimidinoaminoethyl ergoline derivatives
DE2456930A1 (de) * 1974-12-02 1976-08-12 Tesch Kg E Elektronisches zeitspeicherrelais
CH615181A5 (en) * 1975-05-21 1980-01-15 Sandoz Ag Process for the preparation of novel ergolene derivatives
GB2056437A (en) * 1979-08-07 1981-03-18 Erba Farmitalia Secoergoline derivatives
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
DD154897A1 (de) * 1980-12-02 1982-04-28 Seifert Karlheinz Dipl Chem Dr Verfahren zur herstellung von 8-substituierten ergolinen
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
GB2112382B (en) * 1981-11-06 1985-03-06 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
ES531906A0 (es) 1985-06-01
US4690929A (en) 1987-09-01
NO161562C (no) 1989-08-30
IE57240B1 (en) 1992-06-17
NO161562B (no) 1989-05-22
FI81349B (fi) 1990-06-29
KR840008353A (ko) 1984-12-14
ES8506031A1 (es) 1985-06-01
PH21123A (en) 1987-07-27
YU43357B (en) 1989-06-30
FI81349C (fi) 1990-10-10
GR79575B (pt) 1984-10-30
FI841631A0 (pt) 1984-04-25
DK212784D0 (da) 1984-04-27
DK162996C (da) 1992-06-01
HU198713B (en) 1989-11-28
IL71633A (en) 1987-12-20
PT78496B (en) 1986-07-22
AU556968B2 (en) 1986-11-27
IL71633A0 (en) 1984-07-31
KR900008696B1 (ko) 1990-11-27
DK162996B (da) 1992-01-06
NO841657L (no) 1984-10-29
DE3475709D1 (en) 1989-01-26
DK212784A (da) 1984-10-29
HUT34024A (en) 1985-01-28
SU1327788A3 (ru) 1987-07-30
YU74284A (en) 1986-10-31
EP0126968B1 (en) 1988-12-21
CA1205801A (en) 1986-06-10
AU2742184A (en) 1984-11-01
EP0126968A1 (en) 1984-12-05
FI841631A (pt) 1984-10-29

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Legal Events

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MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19970131