PT78114B - Process for the preparation of quinolone carboxylic acids having an antibacterial effect and use thereof for the preparation of pharmaceutical compositions having an antibacterial effect - Google Patents
Process for the preparation of quinolone carboxylic acids having an antibacterial effect and use thereof for the preparation of pharmaceutical compositions having an antibacterial effectInfo
- Publication number
- PT78114B PT78114B PT78114A PT7811484A PT78114B PT 78114 B PT78114 B PT 78114B PT 78114 A PT78114 A PT 78114A PT 7811484 A PT7811484 A PT 7811484A PT 78114 B PT78114 B PT 78114B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- antibacterial effect
- pharmaceutical compositions
- carboxylic acids
- quinolone carboxylic
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 2
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 quinolone carboxylic acids Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833306772 DE3306772A1 (de) | 1983-02-25 | 1983-02-25 | Chinolonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT78114A PT78114A (en) | 1984-03-01 |
| PT78114B true PT78114B (en) | 1986-04-30 |
Family
ID=6191897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT78114A PT78114B (en) | 1983-02-25 | 1984-02-15 | Process for the preparation of quinolone carboxylic acids having an antibacterial effect and use thereof for the preparation of pharmaceutical compositions having an antibacterial effect |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4559342A (pt) |
| EP (1) | EP0117474B1 (pt) |
| JP (1) | JPS59157068A (pt) |
| KR (1) | KR870000891B1 (pt) |
| AR (1) | AR244669A1 (pt) |
| AT (1) | ATE23152T1 (pt) |
| AU (1) | AU562184B2 (pt) |
| CA (1) | CA1216849A (pt) |
| DE (2) | DE3306772A1 (pt) |
| DK (1) | DK103284A (pt) |
| ES (1) | ES8500931A1 (pt) |
| FI (1) | FI83955C (pt) |
| GR (1) | GR79988B (pt) |
| HU (1) | HU192398B (pt) |
| IE (1) | IE56924B1 (pt) |
| IL (1) | IL71036A (pt) |
| NO (1) | NO840557L (pt) |
| NZ (1) | NZ207238A (pt) |
| PH (3) | PH21906A (pt) |
| PT (1) | PT78114B (pt) |
| ZA (1) | ZA841375B (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3306772A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinolonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3306771A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3308908A1 (de) * | 1983-03-12 | 1984-09-13 | Bayer Ag, 5090 Leverkusen | Bakterizide mittel |
| DE3318145A1 (de) * | 1983-05-18 | 1984-11-22 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3420798A1 (de) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren |
| DE3504643A1 (de) * | 1985-02-12 | 1986-08-14 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| IT1200470B (it) * | 1985-05-10 | 1989-01-18 | Schering Spa | Composti ad attivita' antibatterica,loro preparazione e composizioni farmaceutiche relative |
| NZ217650A (en) * | 1985-09-24 | 1989-09-27 | Hoffmann La Roche | Quinoline derivatives and pharmaceutical compositions |
| EP0224121A3 (en) * | 1985-11-19 | 1987-11-11 | ROTTAPHARM S.p.A. | 7-[4-amino-piperazinyl]- or 7-[4-chloro-piperazinyl]quinolinone derivatives, a process for the preparation thereof and pharmaceutical compositions containing them |
| DE3542002A1 (de) * | 1985-11-28 | 1987-06-04 | Bayer Ag | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3705621C2 (de) * | 1986-02-25 | 1997-01-09 | Otsuka Pharma Co Ltd | Heterocyclisch substituierte Chinoloncarbonsäurederivate |
| JPH0811749B2 (ja) * | 1986-03-06 | 1996-02-07 | 富山化学工業株式会社 | 新規なキノリン誘導体およびその塩 |
| DE3902079A1 (de) * | 1988-04-15 | 1989-10-26 | Bayer Ag | I.m. injektionsformen von gyrase-inhibitoren |
| EP0338372A3 (en) * | 1988-04-22 | 1991-10-09 | American Cyanamid Company | Solubilized pro-drugs |
| EP0447484A1 (en) * | 1988-12-06 | 1991-09-25 | The Upjohn Company | Antibacterial quinolone compounds |
| US5262417A (en) * | 1988-12-06 | 1993-11-16 | The Upjohn Company | Antibacterial quinolone compounds |
| WO2004043496A1 (de) * | 2002-11-11 | 2004-05-27 | Austria Wirtschaftsservice Gesellschaft M.B.H. | Fluor-18-markierte fluorchinolone |
| EP2712911A3 (en) | 2009-06-04 | 2014-08-06 | JX Nippon Oil & Energy Corporation | Lubricant oil composition |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149104A (en) * | 1961-01-03 | 1964-09-15 | Sterling Drug Inc | 4-hydroxy-7-styryl-1, 8-naphthyridine-3-carboxylic acids and esters |
| US3590036A (en) * | 1968-11-18 | 1971-06-29 | George Y Lesher | Naphthyridine-3-carboxylic acids,their derivatives and preparation thereof |
| US4017622A (en) * | 1972-12-18 | 1977-04-12 | Dainippon Pharmaceutical Co., Ltd. | Piperazine derivatives |
| SE444566B (sv) * | 1977-09-20 | 1986-04-21 | Bellon Labor Sa Roger | 7-dialkylamin-6-halogen-4-oxo-1,4-dihydrokinolin-3-karboxylsyra, forfarande for framstellning derav och farmaceutiskt preparat derav |
| DE2808070A1 (de) * | 1978-02-24 | 1979-08-30 | Bayer Ag | Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten |
| JPS5845426B2 (ja) * | 1978-09-29 | 1983-10-08 | 杏林製薬株式会社 | 置換キノリンカルボン酸誘導体 |
| DE3142854A1 (de) * | 1981-10-29 | 1983-05-11 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3033157A1 (de) * | 1980-09-03 | 1982-04-01 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| EP0090424B1 (en) * | 1982-03-31 | 1986-05-28 | Sterling Drug Inc. | New quinolone compounds and preparation thereof |
| DE3248505A1 (de) * | 1982-12-29 | 1984-07-05 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(4- (oxoalkyl)-1-piperazinyl/-3-chinolincarbonsaeuren und ihre derivate, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3306771A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinoloncarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3306772A1 (de) * | 1983-02-25 | 1984-08-30 | Bayer Ag, 5090 Leverkusen | Chinolonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
-
1983
- 1983-02-25 DE DE19833306772 patent/DE3306772A1/de not_active Withdrawn
-
1984
- 1984-02-03 US US06/576,596 patent/US4559342A/en not_active Expired - Lifetime
- 1984-02-08 AU AU24283/84A patent/AU562184B2/en not_active Ceased
- 1984-02-13 DE DE8484101443T patent/DE3461087D1/de not_active Expired
- 1984-02-13 EP EP84101443A patent/EP0117474B1/de not_active Expired
- 1984-02-13 AT AT84101443T patent/ATE23152T1/de not_active IP Right Cessation
- 1984-02-15 PT PT78114A patent/PT78114B/pt not_active IP Right Cessation
- 1984-02-15 NO NO840557A patent/NO840557L/no unknown
- 1984-02-21 PH PH30274A patent/PH21906A/en unknown
- 1984-02-22 JP JP59030467A patent/JPS59157068A/ja active Granted
- 1984-02-22 IL IL71036A patent/IL71036A/xx not_active IP Right Cessation
- 1984-02-22 NZ NZ207238A patent/NZ207238A/en unknown
- 1984-02-23 FI FI840747A patent/FI83955C/fi not_active IP Right Cessation
- 1984-02-23 CA CA000448123A patent/CA1216849A/en not_active Expired
- 1984-02-23 GR GR73903A patent/GR79988B/el unknown
- 1984-02-24 DK DK103284A patent/DK103284A/da not_active Application Discontinuation
- 1984-02-24 IE IE443/84A patent/IE56924B1/en not_active IP Right Cessation
- 1984-02-24 ZA ZA841375A patent/ZA841375B/xx unknown
- 1984-02-24 KR KR1019840000914A patent/KR870000891B1/ko not_active IP Right Cessation
- 1984-02-24 ES ES530045A patent/ES8500931A1/es not_active Expired
- 1984-02-24 HU HU84749A patent/HU192398B/hu not_active IP Right Cessation
-
1985
- 1985-07-09 PH PH32498A patent/PH22443A/en unknown
- 1985-07-09 PH PH32499A patent/PH23079A/en unknown
-
1986
- 1986-06-03 AR AR86304202A patent/AR244669A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| US4559342A (en) | 1985-12-17 |
| NZ207238A (en) | 1986-05-09 |
| CA1216849A (en) | 1987-01-20 |
| FI840747A (fi) | 1984-08-26 |
| ZA841375B (en) | 1984-10-31 |
| FI840747A0 (fi) | 1984-02-23 |
| ES530045A0 (es) | 1984-11-01 |
| IL71036A0 (en) | 1984-05-31 |
| JPS59157068A (ja) | 1984-09-06 |
| PT78114A (en) | 1984-03-01 |
| PH21906A (en) | 1988-04-08 |
| ES8500931A1 (es) | 1984-11-01 |
| DE3306772A1 (de) | 1984-08-30 |
| DE3461087D1 (en) | 1986-12-04 |
| EP0117474A1 (de) | 1984-09-05 |
| HU192398B (en) | 1987-06-29 |
| PH22443A (en) | 1988-09-12 |
| FI83955C (fi) | 1991-09-25 |
| AR244669A1 (es) | 1993-11-30 |
| FI83955B (fi) | 1991-06-14 |
| KR870000891B1 (ko) | 1987-05-02 |
| EP0117474B1 (de) | 1986-10-29 |
| NO840557L (no) | 1984-08-27 |
| AU2428384A (en) | 1984-08-30 |
| JPH0430391B2 (pt) | 1992-05-21 |
| IL71036A (en) | 1987-12-31 |
| GR79988B (pt) | 1984-10-31 |
| DK103284D0 (da) | 1984-02-24 |
| DK103284A (da) | 1984-08-26 |
| IE840443L (en) | 1984-08-25 |
| ATE23152T1 (de) | 1986-11-15 |
| KR840008013A (ko) | 1984-12-12 |
| IE56924B1 (en) | 1992-01-29 |
| PH23079A (en) | 1989-04-10 |
| AU562184B2 (en) | 1987-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19991031 |