IL65247A - Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing them - Google Patents
Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL65247A IL65247A IL65247A IL6524782A IL65247A IL 65247 A IL65247 A IL 65247A IL 65247 A IL65247 A IL 65247A IL 6524782 A IL6524782 A IL 6524782A IL 65247 A IL65247 A IL 65247A
- Authority
- IL
- Israel
- Prior art keywords
- acyltetra
- benzazocine
- hydroquinoline
- benzazepine
- isoquinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24540781A | 1981-03-19 | 1981-03-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL65247A0 IL65247A0 (en) | 1982-05-31 |
| IL65247A true IL65247A (en) | 1987-07-31 |
Family
ID=22926526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL65247A IL65247A (en) | 1981-03-19 | 1982-03-15 | Derivatives of n-acyltetra-hydroquinoline,isoquinoline,benzazepine and benzazocine carboxylic acids,process for their preparation and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS57165355A (en) |
| KR (1) | KR890001146B1 (en) |
| AU (1) | AU558451B2 (en) |
| BE (1) | BE892552A (en) |
| CH (1) | CH658455A5 (en) |
| DE (1) | DE3209708A1 (en) |
| DK (1) | DK120982A (en) |
| ES (3) | ES510498A0 (en) |
| FI (1) | FI820974L (en) |
| FR (1) | FR2502149A1 (en) |
| GB (1) | GB2095252B (en) |
| IE (1) | IE53076B1 (en) |
| IL (1) | IL65247A (en) |
| IN (1) | IN156096B (en) |
| IT (1) | IT1150697B (en) |
| NL (1) | NL8201066A (en) |
| NO (1) | NO820903L (en) |
| NZ (1) | NZ200047A (en) |
| PH (1) | PH18657A (en) |
| SE (1) | SE8201654L (en) |
| ZA (1) | ZA821833B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3242599A1 (en) * | 1982-11-18 | 1984-05-24 | Dr. Karl Thomae Gmbh, 7950 Biberach | NEW BENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS |
| US4410520A (en) * | 1981-11-09 | 1983-10-18 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
| US4555502A (en) * | 1982-09-30 | 1985-11-26 | Merck & Co., Inc. | Aminoacyl-containing dipeptide derivatives useful as antihypertensives |
| US4410807A (en) * | 1982-03-26 | 1983-10-18 | Kay Industries, Inc. | Regulating device for polyphase electrical circuits |
| US4473575A (en) * | 1982-07-19 | 1984-09-25 | Ciba-Geigy Corporation | 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids |
| US4520025A (en) * | 1982-07-21 | 1985-05-28 | William H. Rorer, Inc. | Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses |
| DE3302125A1 (en) * | 1983-01-22 | 1984-07-26 | Boehringer Ingelheim KG, 6507 Ingelheim | AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF |
| DK156484A (en) * | 1983-03-16 | 1984-09-17 | Usv Pharma Corp | AMINO ACID DERIVATIVES |
| DE3333454A1 (en) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS |
| DE3622297A1 (en) * | 1986-07-03 | 1988-01-07 | Basf Ag | DISAZOTHIOPHENE DYES |
| US5246943A (en) * | 1992-05-19 | 1993-09-21 | Warner-Lambert Company | Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties |
| ES2122941B1 (en) * | 1997-05-29 | 1999-07-01 | Esteve Quimica Sa | PROCEDURE FOR OBTAINING QUINAPRIL CHLORHYDRATE AND SOLVATES USEFUL FOR THE ISOLATION AND PURIFICATION OF QUINAPRIL CHLORHYDRATE. |
| ES2289060T3 (en) | 2002-01-30 | 2008-02-01 | Les Laboratoires Servier | PROCESS FOR THE PREPARATION OF HIGH PURITY PERINDOPRILE AND USEFUL INTERMEDIATES IN ITS SYNTHESIS. |
| US7482361B2 (en) | 2002-12-16 | 2009-01-27 | Lupin Limited | Crystalline form for quinapril hydrochloride and process for preparing the same |
| DK1603558T3 (en) * | 2003-02-28 | 2008-09-01 | Servier S A Lab | Process for the preparation of perindopril and its salts |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2503155A2 (en) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | NOVEL SUBSTITUTED IMINO DIACIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS AN ENZYME INHIBITOR |
| DE3177311D1 (en) * | 1980-08-30 | 1994-06-09 | Hoechst Ag | Amino acid derivatives, processes for their preparation, compositions containing them and their use. |
| US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| GB2086390B (en) * | 1980-11-03 | 1984-06-06 | Ciba Geigy Ag | 1-carboxy-azaalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application |
-
1982
- 1982-03-08 IN IN265/CAL/82A patent/IN156096B/en unknown
- 1982-03-15 PH PH26998A patent/PH18657A/en unknown
- 1982-03-15 IL IL65247A patent/IL65247A/en unknown
- 1982-03-15 NL NL8201066A patent/NL8201066A/en not_active Application Discontinuation
- 1982-03-16 AU AU81584/82A patent/AU558451B2/en not_active Ceased
- 1982-03-16 SE SE8201654A patent/SE8201654L/en not_active Application Discontinuation
- 1982-03-17 ES ES510498A patent/ES510498A0/en active Granted
- 1982-03-17 DE DE19823209708 patent/DE3209708A1/en not_active Withdrawn
- 1982-03-17 GB GB8207770A patent/GB2095252B/en not_active Expired
- 1982-03-18 CH CH1691/82A patent/CH658455A5/en not_active IP Right Cessation
- 1982-03-18 DK DK120982A patent/DK120982A/en not_active Application Discontinuation
- 1982-03-18 NO NO820903A patent/NO820903L/en unknown
- 1982-03-18 KR KR8201157A patent/KR890001146B1/en active
- 1982-03-18 IT IT20259/82A patent/IT1150697B/en active
- 1982-03-18 NZ NZ200047A patent/NZ200047A/en unknown
- 1982-03-18 ZA ZA821833A patent/ZA821833B/en unknown
- 1982-03-18 JP JP57041801A patent/JPS57165355A/en active Pending
- 1982-03-18 BE BE0/207610A patent/BE892552A/en not_active IP Right Cessation
- 1982-03-19 IE IE635/82A patent/IE53076B1/en unknown
- 1982-03-19 FI FI820974A patent/FI820974L/en not_active Application Discontinuation
- 1982-03-19 FR FR8204738A patent/FR2502149A1/en active Granted
-
1983
- 1983-03-16 ES ES521030A patent/ES8404317A1/en not_active Expired
- 1983-03-16 ES ES521031A patent/ES521031A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IE53076B1 (en) | 1988-06-08 |
| DE3209708A1 (en) | 1982-10-21 |
| ES8307718A1 (en) | 1983-08-01 |
| GB2095252A (en) | 1982-09-29 |
| NZ200047A (en) | 1985-07-12 |
| NL8201066A (en) | 1982-10-18 |
| NO820903L (en) | 1982-09-20 |
| ES8501363A1 (en) | 1984-12-01 |
| AU8158482A (en) | 1982-09-23 |
| CH658455A5 (en) | 1986-11-14 |
| BE892552A (en) | 1982-09-20 |
| SE8201654L (en) | 1982-09-20 |
| IL65247A0 (en) | 1982-05-31 |
| KR830009065A (en) | 1983-12-17 |
| JPS57165355A (en) | 1982-10-12 |
| AU558451B2 (en) | 1987-01-29 |
| ES521030A0 (en) | 1984-05-16 |
| IT1150697B (en) | 1986-12-17 |
| IN156096B (en) | 1985-05-11 |
| FR2502149A1 (en) | 1982-09-24 |
| IE820635L (en) | 1982-09-19 |
| GB2095252B (en) | 1985-04-17 |
| PH18657A (en) | 1985-08-29 |
| ZA821833B (en) | 1983-01-26 |
| ES8404317A1 (en) | 1984-05-16 |
| IT8220259A0 (en) | 1982-03-18 |
| ES510498A0 (en) | 1983-08-01 |
| FR2502149B1 (en) | 1985-01-18 |
| FI820974L (en) | 1982-09-20 |
| KR890001146B1 (en) | 1989-04-25 |
| ES521031A0 (en) | 1984-12-01 |
| DK120982A (en) | 1982-09-20 |
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