IT1150697B - AMID-AMINO ACIDS WITH PHARMACOLOGICAL ACTIVITY AND RELATED PREPARATION PROCEDURE - Google Patents

AMID-AMINO ACIDS WITH PHARMACOLOGICAL ACTIVITY AND RELATED PREPARATION PROCEDURE

Info

Publication number
IT1150697B
IT1150697B IT20259/82A IT2025982A IT1150697B IT 1150697 B IT1150697 B IT 1150697B IT 20259/82 A IT20259/82 A IT 20259/82A IT 2025982 A IT2025982 A IT 2025982A IT 1150697 B IT1150697 B IT 1150697B
Authority
IT
Italy
Prior art keywords
amid
amino acids
pharmacological activity
preparation procedure
related preparation
Prior art date
Application number
IT20259/82A
Other languages
Italian (it)
Other versions
IT8220259A0 (en
Inventor
John T Suh
Jeffrey N Barton
John R Regan
Original Assignee
Usv Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Pharma Corp filed Critical Usv Pharma Corp
Publication of IT8220259A0 publication Critical patent/IT8220259A0/en
Application granted granted Critical
Publication of IT1150697B publication Critical patent/IT1150697B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
IT20259/82A 1981-03-19 1982-03-18 AMID-AMINO ACIDS WITH PHARMACOLOGICAL ACTIVITY AND RELATED PREPARATION PROCEDURE IT1150697B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24540781A 1981-03-19 1981-03-19

Publications (2)

Publication Number Publication Date
IT8220259A0 IT8220259A0 (en) 1982-03-18
IT1150697B true IT1150697B (en) 1986-12-17

Family

ID=22926526

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20259/82A IT1150697B (en) 1981-03-19 1982-03-18 AMID-AMINO ACIDS WITH PHARMACOLOGICAL ACTIVITY AND RELATED PREPARATION PROCEDURE

Country Status (21)

Country Link
JP (1) JPS57165355A (en)
KR (1) KR890001146B1 (en)
AU (1) AU558451B2 (en)
BE (1) BE892552A (en)
CH (1) CH658455A5 (en)
DE (1) DE3209708A1 (en)
DK (1) DK120982A (en)
ES (3) ES510498A0 (en)
FI (1) FI820974L (en)
FR (1) FR2502149A1 (en)
GB (1) GB2095252B (en)
IE (1) IE53076B1 (en)
IL (1) IL65247A (en)
IN (1) IN156096B (en)
IT (1) IT1150697B (en)
NL (1) NL8201066A (en)
NO (1) NO820903L (en)
NZ (1) NZ200047A (en)
PH (1) PH18657A (en)
SE (1) SE8201654L (en)
ZA (1) ZA821833B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3242599A1 (en) * 1982-11-18 1984-05-24 Dr. Karl Thomae Gmbh, 7950 Biberach NEW BENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
US4410520A (en) * 1981-11-09 1983-10-18 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4555502A (en) * 1982-09-30 1985-11-26 Merck & Co., Inc. Aminoacyl-containing dipeptide derivatives useful as antihypertensives
US4410807A (en) * 1982-03-26 1983-10-18 Kay Industries, Inc. Regulating device for polyphase electrical circuits
US4473575A (en) * 1982-07-19 1984-09-25 Ciba-Geigy Corporation 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
US4520025A (en) * 1982-07-21 1985-05-28 William H. Rorer, Inc. Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
DE3302125A1 (en) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF
FI841052A (en) * 1983-03-16 1984-09-17 Usv Pharma Corp FOERENINGAR FOER BEHANDLING AV BLODTRYCKSSJUKDOMAR.
DE3333454A1 (en) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt METHOD FOR PRODUCING N-ALKYLATED DIPEPTIDES AND THEIR ESTERS
DE3622297A1 (en) * 1986-07-03 1988-01-07 Basf Ag DISAZOTHIOPHENE DYES
US5246943A (en) * 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
ES2122941B1 (en) * 1997-05-29 1999-07-01 Esteve Quimica Sa PROCEDURE FOR OBTAINING QUINAPRIL CHLORHYDRATE AND SOLVATES USEFUL FOR THE ISOLATION AND PURIFICATION OF QUINAPRIL CHLORHYDRATE.
DE60220877T2 (en) * 2002-01-30 2008-04-10 Les Laboratoires Servier Process for the preparation of high purity perindopril and intermediates useful in the synthesis
ATE360616T1 (en) 2002-12-16 2007-05-15 Lupin Ltd CRYSTALLINE FORM OF QUINAPRIL HYDROCHLORIDE AND METHOD FOR THE PRODUCTION THEREOF
WO2004075889A1 (en) 2003-02-28 2004-09-10 Lupin Limited Process for preparation of perindopril and salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503155A2 (en) * 1980-10-02 1982-10-08 Science Union & Cie NOVEL SUBSTITUTED IMINO DIACIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS AN ENZYME INHIBITOR
DE3177130D1 (en) * 1980-08-30 1990-01-11 Hoechst Ag AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF.
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
GB2086390B (en) * 1980-11-03 1984-06-06 Ciba Geigy Ag 1-carboxy-azaalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application

Also Published As

Publication number Publication date
FI820974L (en) 1982-09-20
ES8307718A1 (en) 1983-08-01
KR890001146B1 (en) 1989-04-25
AU8158482A (en) 1982-09-23
ES521030A0 (en) 1984-05-16
IL65247A (en) 1987-07-31
GB2095252A (en) 1982-09-29
BE892552A (en) 1982-09-20
DK120982A (en) 1982-09-20
NO820903L (en) 1982-09-20
ES510498A0 (en) 1983-08-01
PH18657A (en) 1985-08-29
IL65247A0 (en) 1982-05-31
CH658455A5 (en) 1986-11-14
FR2502149B1 (en) 1985-01-18
GB2095252B (en) 1985-04-17
KR830009065A (en) 1983-12-17
SE8201654L (en) 1982-09-20
IN156096B (en) 1985-05-11
IE53076B1 (en) 1988-06-08
IE820635L (en) 1982-09-19
ES8404317A1 (en) 1984-05-16
ZA821833B (en) 1983-01-26
DE3209708A1 (en) 1982-10-21
NL8201066A (en) 1982-10-18
JPS57165355A (en) 1982-10-12
NZ200047A (en) 1985-07-12
AU558451B2 (en) 1987-01-29
ES521031A0 (en) 1984-12-01
ES8501363A1 (en) 1984-12-01
FR2502149A1 (en) 1982-09-24
IT8220259A0 (en) 1982-03-18

Similar Documents

Publication Publication Date Title
IT1176983B (en) DIPEPTIDES WITH PHARMACOLOGICAL ACTIVITY
IT1142170B (en) HETEROSYCLIC COMPOUNDS EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION
IT8519512A0 (en) NATURAL DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY
IT1197038B (en) PHARMACEUTICAL COMPOSITION WITH ANALGESIC ACTIVITY
IT1190375B (en) N-BENZHYDRYDIAZACYCLALCHYL-ALCANYLIDES WITH ANTIANAPHYLACTIC AND ANTIBRONCOSPASTIC ACTIVITY
IT7849577A0 (en) SPIROAMINE DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY AND RELATED PRODUCTION PROCEDURE
IT1150697B (en) AMID-AMINO ACIDS WITH PHARMACOLOGICAL ACTIVITY AND RELATED PREPARATION PROCEDURE
IT1186717B (en) BENZOIL-UREE WITH INSECTICIDE ACTIVITY
IT1150622B (en) POLYSACCHARIDES EQUIPPED WITH ANTI-CARCINOGENE ACTIVITY AND PROCEDURE FOR THEIR PREPARATION
IT1205123B (en) BIPHENYL-HYDROXAMIC ACIDS
IT1187756B (en) ISOINDOLINIL-ALCHIL-PIPERAZINE WITH PHARMACEUTICAL ACTIVITY
AR231144A1 (en) PROCEDURE FOR THE PREPARATION OF 5'-DESOXI-5'-METHYLTICADENOSINE WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY
IT1178792B (en) ACILAMINO MITOSANI WITH ANTI-TUMOR ACTIVITY AND RELATED PREPARATION PROCEDURE
IT1190130B (en) 3-ACYLAMINO-2-BONE-1-AZETIDINSOLFONICI ACIDS
IT1164826B (en) EPOXY-SUCCINAMIC ACID COMPOUNDS EQUIPPED WITH PHARMACOLOGICAL PROPERTIES AND PREPARATION PROCEDURE
IT7920398A0 (en) DERIVED FROM ENHANCED ANTI-INFLAMMATORY ANALGESIC ACTIVITY AND PROCEDURE FOR ITS PREPARATION.
IT1128706B (en) PROCEDURE FOR THE PREPARATION OF ARYLPROPIONIC ACIDS EQUIPPED WITH PHARMACOLOGICAL ACTIVITY
BE893322A (en) PREPARATION OF CARBOXYLIC ACIDS
IT8721328A0 (en) HYDROXYMIC ACIDS OF ETHERS AND DITHIOETHERS 7 SUBSTITUTED OXABICICLOHEPTANS.
IT8247833A0 (en) WATER SOLUBLE CHOLESTEROL DERIVATIVE WITH PHARMACOLOGICAL ACTIVITY AND PREPARATION PROCEDURE
NO862548L (en) PREPARATION OF 3-AMINO-4-HYDROXY-BENZO ACIDS.
IT1188557B (en) ACIDS 8-BONE-2-BONE-1-AZABICYCLE (4.2.0) OCTANE-3-CARBOXYLIC
ES545117A0 (en) PROCEDURE FOR THE PREPARATION OF NEW ACID DERIVATIVES- 9- OR 11-NITROAPROVINCAMINICO RACEMICOS AND OPTICAMENTE ACTIVOS
FR2510117B1 (en) NOVEL HYDRAZONOCEPHEM DERIVATIVES AND THEIR PHARMACOLOGICAL APPLICATION
IT1149073B (en) 4-PYRIDYLPYRIDAZINONE DERIVATIVES EQUIPPED WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY