PT75023B - Procede de preparation de nouveaux derives du n-dihydrothiazolyl 3-quinoleine carboxamide - Google Patents
Procede de preparation de nouveaux derives du n-dihydrothiazolyl 3-quinoleine carboxamideInfo
- Publication number
- PT75023B PT75023B PT75023A PT7502382A PT75023B PT 75023 B PT75023 B PT 75023B PT 75023 A PT75023 A PT 75023A PT 7502382 A PT7502382 A PT 7502382A PT 75023 B PT75023 B PT 75023B
- Authority
- PT
- Portugal
- Prior art keywords
- dihydrothiazolyl
- novel
- preparation
- carboxamide derivatives
- quinoline carboxamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8111607A FR2507602A1 (fr) | 1981-06-12 | 1981-06-12 | Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
| FR8204331A FR2523130A1 (fr) | 1982-03-15 | 1982-03-15 | Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT75023A PT75023A (fr) | 1982-07-01 |
| PT75023B true PT75023B (fr) | 1985-05-17 |
Family
ID=26222434
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT75023A PT75023B (fr) | 1981-06-12 | 1982-06-08 | Procede de preparation de nouveaux derives du n-dihydrothiazolyl 3-quinoleine carboxamide |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4450166A (pt) |
| EP (1) | EP0067772B1 (pt) |
| KR (1) | KR880000808B1 (pt) |
| AU (1) | AU552029B2 (pt) |
| CA (1) | CA1216795A (pt) |
| DE (1) | DE3262536D1 (pt) |
| DK (1) | DK150070C (pt) |
| ES (1) | ES8304567A1 (pt) |
| FI (1) | FI78087C (pt) |
| GR (1) | GR77201B (pt) |
| HU (1) | HU190796B (pt) |
| IE (1) | IE53520B1 (pt) |
| IL (1) | IL65943A (pt) |
| MA (1) | MA19488A1 (pt) |
| NZ (1) | NZ200931A (pt) |
| PT (1) | PT75023B (pt) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2557570B1 (fr) * | 1984-01-04 | 1986-04-18 | Adir | Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| FR2566405B1 (fr) * | 1984-06-25 | 1986-09-26 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus |
| US4602014A (en) * | 1984-07-09 | 1986-07-22 | Ciba-Geigy Corporation | Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators |
| US4560692A (en) * | 1984-07-18 | 1985-12-24 | Hoffmann-La Roche Inc. | 4-Piperidino-2-phenylquinolines |
| US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
| BR9908321A (pt) | 1998-02-26 | 2001-12-18 | Neurogen Corp | Composto |
| BR0010308A (pt) * | 1999-05-06 | 2002-01-08 | Neurogen Corp | Composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento de uma doença ou distúrbio associados com o agonismo patogênico, agonismo inverso ou antagonismo do receptor de gabaa, para localizar receptores de gabaa em uma amostra de tecido, para inibir a ligação de um composto de benzodiazepina a um receptor de gabaa e para alterar a atividade da transdução de sinal dos receptores de gabaa, e, composição farmacêutica embalada |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| US8354427B2 (en) * | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| ES2656017T3 (es) | 2004-06-24 | 2018-02-22 | Vertex Pharmaceuticals Incorporated | Moduladores de transportadores del casete de unión a ATP |
| WO2007075901A2 (en) * | 2005-12-24 | 2007-07-05 | Vertex Pharmaceuticals Incorporated | Quinolin- 4 - one derivatives as modulators of abc transporters |
| DK3219705T3 (da) | 2005-12-28 | 2020-04-14 | Vertex Pharma | Farmaceutiske sammensætninger af den amorfe form af n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid |
| EP3330255B1 (en) | 2009-03-20 | 2020-12-09 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| AU2013226076B2 (en) | 2012-02-27 | 2017-11-16 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administration thereof |
| JP6746569B2 (ja) | 2014-10-07 | 2020-08-26 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 嚢胞性線維症膜貫通コンダクタンス制御因子のモジュレーターの共結晶 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1364605A (fr) * | 1962-03-01 | 1964-06-26 | Procédé de préparation d'amides des acides carboxyliques | |
| FR2281761A1 (fr) * | 1974-08-13 | 1976-03-12 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2324304A2 (fr) * | 1975-09-22 | 1977-04-15 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2340735A1 (fr) * | 1976-02-11 | 1977-09-09 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2377400A2 (fr) * | 1977-01-18 | 1978-08-11 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2443467A1 (fr) * | 1978-12-08 | 1980-07-04 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
| FR2482596A1 (fr) * | 1980-05-19 | 1981-11-20 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament |
-
1982
- 1982-05-24 HU HU821657A patent/HU190796B/hu not_active IP Right Cessation
- 1982-05-26 MA MA19695A patent/MA19488A1/fr unknown
- 1982-06-01 IL IL65943A patent/IL65943A/xx unknown
- 1982-06-04 ES ES512852A patent/ES8304567A1/es not_active Expired
- 1982-06-08 PT PT75023A patent/PT75023B/pt not_active IP Right Cessation
- 1982-06-09 US US06/386,597 patent/US4450166A/en not_active Expired - Fee Related
- 1982-06-10 GR GR68384A patent/GR77201B/el unknown
- 1982-06-10 FI FI822067A patent/FI78087C/fi not_active IP Right Cessation
- 1982-06-11 DK DK262782A patent/DK150070C/da not_active IP Right Cessation
- 1982-06-11 KR KR8202613A patent/KR880000808B1/ko active
- 1982-06-11 IE IE1394/82A patent/IE53520B1/en unknown
- 1982-06-11 NZ NZ200931A patent/NZ200931A/en unknown
- 1982-06-11 EP EP82401062A patent/EP0067772B1/fr not_active Expired
- 1982-06-11 CA CA000405006A patent/CA1216795A/fr not_active Expired
- 1982-06-11 DE DE8282401062T patent/DE3262536D1/de not_active Expired
- 1982-06-11 AU AU84827/82A patent/AU552029B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MA19488A1 (fr) | 1982-12-31 |
| GR77201B (pt) | 1984-09-11 |
| IL65943A0 (en) | 1982-09-30 |
| KR880000808B1 (ko) | 1988-05-11 |
| AU8482782A (en) | 1982-12-16 |
| DK150070C (da) | 1987-11-09 |
| DK150070B (da) | 1986-12-01 |
| PT75023A (fr) | 1982-07-01 |
| ES512852A0 (es) | 1983-03-01 |
| NZ200931A (en) | 1984-12-14 |
| IE821394L (en) | 1982-12-12 |
| EP0067772B1 (fr) | 1985-03-13 |
| EP0067772A1 (fr) | 1982-12-22 |
| DE3262536D1 (en) | 1985-04-18 |
| ES8304567A1 (es) | 1983-03-01 |
| HU190796B (en) | 1986-11-28 |
| KR840000541A (ko) | 1984-02-25 |
| FI822067A0 (fi) | 1982-06-10 |
| US4450166A (en) | 1984-05-22 |
| FI78087B (fi) | 1989-02-28 |
| IL65943A (en) | 1985-12-31 |
| CA1216795A (fr) | 1987-01-20 |
| DK262782A (da) | 1982-12-13 |
| FI78087C (fi) | 1989-06-12 |
| IE53520B1 (en) | 1988-12-07 |
| AU552029B2 (en) | 1986-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19911130 |