ES512852A0 - "un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida". - Google Patents
"un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida".Info
- Publication number
- ES512852A0 ES512852A0 ES512852A ES512852A ES512852A0 ES 512852 A0 ES512852 A0 ES 512852A0 ES 512852 A ES512852 A ES 512852A ES 512852 A ES512852 A ES 512852A ES 512852 A0 ES512852 A0 ES 512852A0
- Authority
- ES
- Spain
- Prior art keywords
- dihydrotiazolyl
- quinolein
- carboxamide
- procedure
- new derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8111607A FR2507602A1 (fr) | 1981-06-12 | 1981-06-12 | Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
FR8204331A FR2523130A1 (fr) | 1982-03-15 | 1982-03-15 | Nouveaux derives de la n-dihydrothiazolyl-3-quinoleine carboxamide, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8304567A1 ES8304567A1 (es) | 1983-03-01 |
ES512852A0 true ES512852A0 (es) | 1983-03-01 |
Family
ID=26222434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512852A Granted ES512852A0 (es) | 1981-06-12 | 1982-06-04 | "un procedimiento para preparar nuevos derivados de la n-dihidrotiazolil-3-quinolein-carboxamida". |
Country Status (16)
Country | Link |
---|---|
US (1) | US4450166A (es) |
EP (1) | EP0067772B1 (es) |
KR (1) | KR880000808B1 (es) |
AU (1) | AU552029B2 (es) |
CA (1) | CA1216795A (es) |
DE (1) | DE3262536D1 (es) |
DK (1) | DK150070C (es) |
ES (1) | ES512852A0 (es) |
FI (1) | FI78087C (es) |
GR (1) | GR77201B (es) |
HU (1) | HU190796B (es) |
IE (1) | IE53520B1 (es) |
IL (1) | IL65943A (es) |
MA (1) | MA19488A1 (es) |
NZ (1) | NZ200931A (es) |
PT (1) | PT75023B (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2557570B1 (fr) * | 1984-01-04 | 1986-04-18 | Adir | Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
FR2566405B1 (fr) * | 1984-06-25 | 1986-09-26 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2 par une fonction aminee, leur preparation, leur application comme medicaments, les compositions les renfermant et les intermediaires nouveaux obtenus |
US4602014A (en) * | 1984-07-09 | 1986-07-22 | Ciba-Geigy Corporation | Ring-fused pyrazolo[3,4-d]-pyridin-3-one derivatives as benzodiazepine receptor modulators |
US4560692A (en) * | 1984-07-18 | 1985-12-24 | Hoffmann-La Roche Inc. | 4-Piperidino-2-phenylquinolines |
US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
JP2002504544A (ja) | 1998-02-26 | 2002-02-12 | ニューロゲン コーポレイション | 置換されたシクロアルキル−4−オキソニコチン酸カルボキシアミド;gaba脳受容体リガンド |
CA2371472A1 (en) * | 1999-05-06 | 2000-11-16 | Neurogen Corporation | Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands |
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
BR122018075478B8 (pt) * | 2004-06-24 | 2023-10-31 | Vertex Pharma | moduladores de transportadores de cassete de ligação de atp |
US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
US20090105272A1 (en) * | 2005-12-24 | 2009-04-23 | Grootenhuis Peter D J | Prodrugs of modulators of ABC transporters |
HUE049976T2 (hu) | 2005-12-28 | 2020-11-30 | Vertex Pharma | N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói |
SG10201504084QA (en) | 2009-03-20 | 2015-06-29 | Vertex Pharma | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
CN109966264A (zh) | 2012-02-27 | 2019-07-05 | 沃泰克斯药物股份有限公司 | 药物组合物及其施用 |
CN107250113B (zh) | 2014-10-07 | 2019-03-29 | 弗特克斯药品有限公司 | 囊性纤维化跨膜传导调节蛋白的调节剂的共晶 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1364605A (fr) * | 1962-03-01 | 1964-06-26 | Procédé de préparation d'amides des acides carboxyliques | |
FR2281761A1 (fr) * | 1974-08-13 | 1976-03-12 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
FR2324304A2 (fr) * | 1975-09-22 | 1977-04-15 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
FR2340735A1 (fr) * | 1976-02-11 | 1977-09-09 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
FR2377400A2 (fr) * | 1977-01-18 | 1978-08-11 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
FR2443467A1 (fr) * | 1978-12-08 | 1980-07-04 | Roussel Uclaf | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
FR2482596A1 (fr) * | 1980-05-19 | 1981-11-20 | Roussel Uclaf | Nouveaux derives de l'acide 4-hydroxy 3-quinoleine carboxylique substitues en 2, leur procede de preparation et leur application comme medicament |
-
1982
- 1982-05-24 HU HU821657A patent/HU190796B/hu not_active IP Right Cessation
- 1982-05-26 MA MA19695A patent/MA19488A1/fr unknown
- 1982-06-01 IL IL65943A patent/IL65943A/xx unknown
- 1982-06-04 ES ES512852A patent/ES512852A0/es active Granted
- 1982-06-08 PT PT75023A patent/PT75023B/pt not_active IP Right Cessation
- 1982-06-09 US US06/386,597 patent/US4450166A/en not_active Expired - Fee Related
- 1982-06-10 GR GR68384A patent/GR77201B/el unknown
- 1982-06-10 FI FI822067A patent/FI78087C/fi not_active IP Right Cessation
- 1982-06-11 EP EP82401062A patent/EP0067772B1/fr not_active Expired
- 1982-06-11 AU AU84827/82A patent/AU552029B2/en not_active Ceased
- 1982-06-11 CA CA000405006A patent/CA1216795A/fr not_active Expired
- 1982-06-11 NZ NZ200931A patent/NZ200931A/en unknown
- 1982-06-11 IE IE1394/82A patent/IE53520B1/en unknown
- 1982-06-11 KR KR8202613A patent/KR880000808B1/ko active
- 1982-06-11 DE DE8282401062T patent/DE3262536D1/de not_active Expired
- 1982-06-11 DK DK262782A patent/DK150070C/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0067772A1 (fr) | 1982-12-22 |
MA19488A1 (fr) | 1982-12-31 |
IL65943A0 (en) | 1982-09-30 |
DK150070C (da) | 1987-11-09 |
GR77201B (es) | 1984-09-11 |
IE821394L (en) | 1982-12-12 |
PT75023B (fr) | 1985-05-17 |
EP0067772B1 (fr) | 1985-03-13 |
NZ200931A (en) | 1984-12-14 |
KR880000808B1 (ko) | 1988-05-11 |
FI78087B (fi) | 1989-02-28 |
IE53520B1 (en) | 1988-12-07 |
ES8304567A1 (es) | 1983-03-01 |
FI822067A0 (fi) | 1982-06-10 |
DK262782A (da) | 1982-12-13 |
HU190796B (en) | 1986-11-28 |
AU8482782A (en) | 1982-12-16 |
AU552029B2 (en) | 1986-05-22 |
DE3262536D1 (en) | 1985-04-18 |
KR840000541A (ko) | 1984-02-25 |
PT75023A (fr) | 1982-07-01 |
CA1216795A (fr) | 1987-01-20 |
DK150070B (da) | 1986-12-01 |
IL65943A (en) | 1985-12-31 |
US4450166A (en) | 1984-05-22 |
FI78087C (fi) | 1989-06-12 |
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