PT741788E - Inducao de tolerancia com proteinas de fusao tolerogenicas - Google Patents

Inducao de tolerancia com proteinas de fusao tolerogenicas

Info

Publication number
PT741788E
PT741788E PT95910220T PT95910220T PT741788E PT 741788 E PT741788 E PT 741788E PT 95910220 T PT95910220 T PT 95910220T PT 95910220 T PT95910220 T PT 95910220T PT 741788 E PT741788 E PT 741788E
Authority
PT
Portugal
Prior art keywords
tolerogenic
epitopes
immunoglobulin
tolerance
inducing
Prior art date
Application number
PT95910220T
Other languages
English (en)
Inventor
David W Scott
Elias T Zambidis
Original Assignee
American Nat Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Nat Red Cross filed Critical American Nat Red Cross
Publication of PT741788E publication Critical patent/PT741788E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
PT95910220T 1994-02-14 1995-02-10 Inducao de tolerancia com proteinas de fusao tolerogenicas PT741788E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/195,874 US5817308A (en) 1994-02-14 1994-02-14 Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance

Publications (1)

Publication Number Publication Date
PT741788E true PT741788E (pt) 2005-05-31

Family

ID=22723177

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95910220T PT741788E (pt) 1994-02-14 1995-02-10 Inducao de tolerancia com proteinas de fusao tolerogenicas

Country Status (10)

Country Link
US (2) US5817308A (pt)
EP (1) EP0741788B1 (pt)
JP (2) JPH09509316A (pt)
AT (1) ATE288494T1 (pt)
CA (1) CA2182977A1 (pt)
DE (1) DE69533979T8 (pt)
DK (1) DK0741788T3 (pt)
ES (1) ES2233940T3 (pt)
PT (1) PT741788E (pt)
WO (1) WO1995021926A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817308A (en) * 1994-02-14 1998-10-06 University Of Rochester Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance
US6485726B1 (en) * 1995-01-17 2002-11-26 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
US5843462A (en) * 1995-11-30 1998-12-01 Regents Of The University Of Minnesota Diphtheria toxin epitopes
WO1999030736A2 (en) 1997-12-16 1999-06-24 Regents Of The University Of Minnesota Methods to treat undesirable immune responses
AU753310B2 (en) * 1998-05-20 2002-10-17 Chugai Seiyaku Kabushiki Kaisha Novel method for gene cloning
US6884785B2 (en) * 1999-06-17 2005-04-26 The Scripps Research Institute Compositions and methods for the treatment or prevention of autoimmune diabetes
DE50112965D1 (de) * 2000-04-22 2007-10-18 Pharmedartis Gmbh Apoptotika
US7498162B2 (en) 2000-09-25 2009-03-03 Nestec S.A. Lactic acid bacteria capable of reducing an individual's tendency to develop allergic reactions
US8703146B2 (en) * 2001-04-20 2014-04-22 Institute For Systems Biology Toll-like receptor 5 ligands and methods of use
DE60141773D1 (de) * 2001-04-20 2010-05-20 Inst Systems Biology Toll-ähnlichen-rezeptor-5-liganden und verwendungsverfahren
US20120148585A1 (en) * 2001-05-01 2012-06-14 Andrew Saxon Fusion molecules and methods for treatment of immune diseases
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
US7744876B2 (en) 2002-04-09 2010-06-29 The Curators Of The University Of Missouri Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes
US8603471B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions for preventing the onset of type 1 diabetes
US8603472B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide
US8609091B2 (en) 2002-04-09 2013-12-17 The Curators Of The University Of Missouri Method for endocytic presentation of an immunosuppressive for the treatment of type 1 diabetes
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
BRPI0617330A2 (pt) * 2005-10-13 2011-07-19 Virexx Medical Corp antìgeno quimérico contendo polipeptìdeo do vìrus da hepatite c e fragmento fc para despertar uma resposta imunológica
EP2450366A1 (en) 2007-01-30 2012-05-09 Epivax, Inc. Regulatory t cell epitopes, compositions and uses thereof
NZ595060A (en) 2009-03-23 2013-05-31 Pin Pharma Inc Treatment of cancer with immunostimulatory hiv tat derivative polypeptides
EA201491748A1 (ru) 2012-03-23 2015-02-27 Дзе Юниверсити Оф Квинсленд Иммуномодулирующие средства и способы их применения
RU2695653C2 (ru) 2013-10-04 2019-07-25 Пин Фарма, Инк. Иммуностимулирующие полипептидные производные тат вич для применения в лечении рака

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69023900T4 (de) * 1989-02-24 1996-10-02 Univ California Gentechnologisch veränderte immunglobuline.
GB9021679D0 (en) * 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
US6248332B1 (en) * 1990-10-05 2001-06-19 Medarex, Inc. Targeted immunostimulation with bispecific reagents
US5167956A (en) * 1991-02-11 1992-12-01 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin with in-vivo t cell suppressant activity
US5817308A (en) * 1994-02-14 1998-10-06 University Of Rochester Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance

Also Published As

Publication number Publication date
WO1995021926A1 (en) 1995-08-17
DE69533979T8 (de) 2006-11-09
JP2008001709A (ja) 2008-01-10
US20020048562A1 (en) 2002-04-25
EP0741788A1 (en) 1996-11-13
JPH09509316A (ja) 1997-09-22
DK0741788T3 (da) 2005-05-30
US6838281B2 (en) 2005-01-04
DE69533979D1 (de) 2005-03-10
DE69533979T2 (de) 2006-04-27
JP4214173B2 (ja) 2009-01-28
ATE288494T1 (de) 2005-02-15
US5817308A (en) 1998-10-06
EP0741788B1 (en) 2005-02-02
CA2182977A1 (en) 1995-08-17
ES2233940T3 (es) 2005-06-16

Similar Documents

Publication Publication Date Title
PT741788E (pt) Inducao de tolerancia com proteinas de fusao tolerogenicas
DK0700445T3 (da) Stressproteiner og anvendelser deraf
Sell Studies on rabbit lymphocytes in vitro: VI. The induction of blast transformation with sheep antisera to rabbit IgA and IgM
ATE353362T1 (de) Neuartige ctla4/cd28 liganden und deren anwendungen
DE69023900T2 (de) Gentechnologisch veränderte immunglobuline.
ZA924271B (en) Tri-and tetravalent mono specific antigen binding proteins
SE9201331D0 (sv) Protein l och hybridproteiner daerav
DE3484664D1 (de) Rekombinante immunoglobulin-praeparate, verfahren zu ihrer herstellung, dna-sequenzen, expressionsvektoren und rekombinante wirkzellen hierfuer.
ATE280227T1 (de) Epitope von stress proteinen
EP0245078A3 (en) Enhancement of antigen immunogenicity
US5043429B1 (en) Protein fragments containing factor VIII binding domain of von willebrand factor
DE69034100D1 (de) Verktorvermittelte genominsertion und expression von dna in bcg
DE69328726D1 (de) Verwendung synthetischer peptide zur induktion der toleranz gegen t- und b-zell epitope von autoantigenen
ZA9210006B (en) Anti-human IgE monoclonal antibodies.
Pedersen et al. Antigenic Analysis of Treponema pallidum: Cross‐reactions between Individual Antigens of T. pallidum and T. Reiter
DK0625157T3 (da) Blodplade-GPIIIaP1A1- og -P1A2-epitoper og fremstilling og anvendelse deraf
Itoh et al. Synthesis and secretion of alpha 1-microglobulin by human lymphocytes.
Koch et al. Association of surface IgM with two membrane proteins on murine B lymphocytes detected by chemical crosslinking
Ikeda et al. Evidence for polymorphism of MB3 antigens among three HLA-D clusters associated with HLA-DR4
WO1999042478A3 (en) LEPTOSPIRAL OUTER MEMBRANE PROTEIN, LipL32
Williams et al. Rheumatoid factors from patients with rheumatoid arthritis react with Des‐Lys58‐β2m, modified β2‐microglobulin
Patel Purification and characterization of Bovine CD36 from heart microsomes