ATE288494T1 - Toleranzinduktion mit tolerogenischen fusionsproteinen - Google Patents

Toleranzinduktion mit tolerogenischen fusionsproteinen

Info

Publication number
ATE288494T1
ATE288494T1 AT95910220T AT95910220T ATE288494T1 AT E288494 T1 ATE288494 T1 AT E288494T1 AT 95910220 T AT95910220 T AT 95910220T AT 95910220 T AT95910220 T AT 95910220T AT E288494 T1 ATE288494 T1 AT E288494T1
Authority
AT
Austria
Prior art keywords
epitopes
tolerogenic
immunoglobulin
inducing
provides methods
Prior art date
Application number
AT95910220T
Other languages
English (en)
Inventor
David W Scott
Elias T Zambidis
Original Assignee
American Nat Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Nat Red Cross filed Critical American Nat Red Cross
Application granted granted Critical
Publication of ATE288494T1 publication Critical patent/ATE288494T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fuses (AREA)
  • Burglar Alarm Systems (AREA)
  • Control Of High-Frequency Heating Circuits (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
AT95910220T 1994-02-14 1995-02-10 Toleranzinduktion mit tolerogenischen fusionsproteinen ATE288494T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/195,874 US5817308A (en) 1994-02-14 1994-02-14 Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance
PCT/US1995/001671 WO1995021926A1 (en) 1994-02-14 1995-02-10 Inducing tolerance with tolerogenic fusion proteins

Publications (1)

Publication Number Publication Date
ATE288494T1 true ATE288494T1 (de) 2005-02-15

Family

ID=22723177

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910220T ATE288494T1 (de) 1994-02-14 1995-02-10 Toleranzinduktion mit tolerogenischen fusionsproteinen

Country Status (10)

Country Link
US (2) US5817308A (de)
EP (1) EP0741788B1 (de)
JP (2) JPH09509316A (de)
AT (1) ATE288494T1 (de)
CA (1) CA2182977A1 (de)
DE (1) DE69533979T8 (de)
DK (1) DK0741788T3 (de)
ES (1) ES2233940T3 (de)
PT (1) PT741788E (de)
WO (1) WO1995021926A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817308A (en) * 1994-02-14 1998-10-06 University Of Rochester Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance
US6485726B1 (en) * 1995-01-17 2002-11-26 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
US5843462A (en) * 1995-11-30 1998-12-01 Regents Of The University Of Minnesota Diphtheria toxin epitopes
CA2315537A1 (en) 1997-12-16 1999-06-24 Regents Of The University Of Minnesota Methods to treat undesirable immune responses
KR100518958B1 (ko) * 1998-05-20 2005-10-06 추가이 세이야쿠 가부시키가이샤 신규한 유전자 클로닝 방법
US6884785B2 (en) * 1999-06-17 2005-04-26 The Scripps Research Institute Compositions and methods for the treatment or prevention of autoimmune diabetes
WO2001080880A2 (de) * 2000-04-22 2001-11-01 Stefan Barth Apoptotika
IL154284A0 (en) * 2000-09-25 2003-09-17 Nestle Sa Lactic acid bacteria capable of reducing an individual's tendency to develop allergic reactions
US8703146B2 (en) * 2001-04-20 2014-04-22 Institute For Systems Biology Toll-like receptor 5 ligands and methods of use
WO2002085933A1 (en) * 2001-04-20 2002-10-31 The Institute For Systems Biology Toll-like receptor 5 ligands and methods of use
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
US20120148585A1 (en) * 2001-05-01 2012-06-14 Andrew Saxon Fusion molecules and methods for treatment of immune diseases
US7744876B2 (en) 2002-04-09 2010-06-29 The Curators Of The University Of Missouri Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes
US8603472B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide
US8609091B2 (en) 2002-04-09 2013-12-17 The Curators Of The University Of Missouri Method for endocytic presentation of an immunosuppressive for the treatment of type 1 diabetes
US8603471B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions for preventing the onset of type 1 diabetes
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
CN101300355A (zh) * 2005-10-13 2008-11-05 威瑞克斯医药公司 包含丙型肝炎病毒多肽和用于引起免疫应答的Fc片段的嵌合抗原
EP2423222B2 (de) * 2007-01-30 2020-07-29 Epivax, Inc. Regulatorische T-Zellen-Epitopen sowie Zusammensetzungen damit und Anwendungen davon
CN102405057B (zh) 2009-03-23 2016-05-25 那尼尔科斯治疗公司 用免疫刺激性Hiv Tat衍生物多肽治疗癌症
KR20150010716A (ko) 2012-03-23 2015-01-28 더 유니버시티 오브 퀸스랜드 면역조절제 및 이의 용도
CA2926221A1 (en) 2013-10-04 2015-04-09 Pin Pharma, Inc. Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2047244C (en) * 1989-02-24 2002-09-17 Zanetti Maurizio Genetically engineered immunoglobulins
US6248332B1 (en) * 1990-10-05 2001-06-19 Medarex, Inc. Targeted immunostimulation with bispecific reagents
GB9021679D0 (en) * 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
US5167956A (en) * 1991-02-11 1992-12-01 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin with in-vivo t cell suppressant activity
US5817308A (en) * 1994-02-14 1998-10-06 University Of Rochester Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance

Also Published As

Publication number Publication date
EP0741788A1 (de) 1996-11-13
DK0741788T3 (da) 2005-05-30
DE69533979T8 (de) 2006-11-09
PT741788E (pt) 2005-05-31
JP2008001709A (ja) 2008-01-10
CA2182977A1 (en) 1995-08-17
ES2233940T3 (es) 2005-06-16
DE69533979T2 (de) 2006-04-27
US20020048562A1 (en) 2002-04-25
JPH09509316A (ja) 1997-09-22
EP0741788B1 (de) 2005-02-02
US6838281B2 (en) 2005-01-04
DE69533979D1 (de) 2005-03-10
US5817308A (en) 1998-10-06
JP4214173B2 (ja) 2009-01-28
WO1995021926A1 (en) 1995-08-17

Similar Documents

Publication Publication Date Title
DE69533979D1 (de) Toleranzinduktion mit tolerogenischen Fusionsproteinen
PT700445E (pt) Proteinas de stress e suas utilizacoes
Sell Studies on rabbit lymphocytes in vitro: VI. The induction of blast transformation with sheep antisera to rabbit IgA and IgM
ATE353362T1 (de) Neuartige ctla4/cd28 liganden und deren anwendungen
EP0460076A4 (en) Genetically engineered immunoglobulins
ZA924271B (en) Tri-and tetravalent mono specific antigen binding proteins
SE9201331D0 (sv) Protein l och hybridproteiner daerav
EP0699755A3 (de) Verfahren zur Herstellung modifizierter Immunoglobulinen mit reduzierter Immunogenität der variablen Domänen einer murinen Antikörpers, Zusammensetzungen die diese enthalten
EP0245078A3 (en) Enhancement of antigen immunogenicity
ATE280227T1 (de) Epitope von stress proteinen
US5043429B1 (en) Protein fragments containing factor VIII binding domain of von willebrand factor
ATE250133T1 (de) Verktorvermittelte genominsertion und expression von dna in bcg
DE69328726D1 (de) Verwendung synthetischer peptide zur induktion der toleranz gegen t- und b-zell epitope von autoantigenen
Cooper et al. Isolation of a murine leukemia Fc receptor by selective release induced by surface redistribution
EP0550020A3 (en) Anti-human ige monoclonal antibodies
Pedersen et al. Antigenic Analysis of Treponema pallidum: Cross‐reactions between Individual Antigens of T. pallidum and T. Reiter
SG95574A1 (en) Immunoreactive antigens of hepatitia e virus
DK0625157T3 (da) Blodplade-GPIIIaP1A1- og -P1A2-epitoper og fremstilling og anvendelse deraf
Itoh et al. Synthesis and secretion of alpha 1-microglobulin by human lymphocytes.
Ikeda et al. Evidence for polymorphism of MB3 antigens among three HLA-D clusters associated with HLA-DR4
WO1999042478A3 (en) LEPTOSPIRAL OUTER MEMBRANE PROTEIN, LipL32
ATE201046T1 (de) Polypeptide und dafür kodierende dns, die mit humanen malariaparasiten assoziiert sind
BRANDTZAEG Immunological Removal of Contaminants: a Useful Principle in Protein Purification Applied to Human Secretory Component and J Chain
Patel Purification and characterization of Bovine CD36 from heart microsomes

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0741788

Country of ref document: EP

REN Ceased due to non-payment of the annual fee