DK0741788T3 - Induktion af tolerans med tolerogene fusionsproteiner - Google Patents

Induktion af tolerans med tolerogene fusionsproteiner

Info

Publication number
DK0741788T3
DK0741788T3 DK95910220T DK95910220T DK0741788T3 DK 0741788 T3 DK0741788 T3 DK 0741788T3 DK 95910220 T DK95910220 T DK 95910220T DK 95910220 T DK95910220 T DK 95910220T DK 0741788 T3 DK0741788 T3 DK 0741788T3
Authority
DK
Denmark
Prior art keywords
epitopes
immunoglobulin
tolerogenic
tolerance
inducing
Prior art date
Application number
DK95910220T
Other languages
Danish (da)
English (en)
Inventor
David W Scott
Elias T Zambidis
Original Assignee
American Nat Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Nat Red Cross filed Critical American Nat Red Cross
Application granted granted Critical
Publication of DK0741788T3 publication Critical patent/DK0741788T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fuses (AREA)
  • Burglar Alarm Systems (AREA)
  • Control Of High-Frequency Heating Circuits (AREA)
  • Lining Or Joining Of Plastics Or The Like (AREA)
DK95910220T 1994-02-14 1995-02-10 Induktion af tolerans med tolerogene fusionsproteiner DK0741788T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/195,874 US5817308A (en) 1994-02-14 1994-02-14 Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance
PCT/US1995/001671 WO1995021926A1 (en) 1994-02-14 1995-02-10 Inducing tolerance with tolerogenic fusion proteins

Publications (1)

Publication Number Publication Date
DK0741788T3 true DK0741788T3 (da) 2005-05-30

Family

ID=22723177

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95910220T DK0741788T3 (da) 1994-02-14 1995-02-10 Induktion af tolerans med tolerogene fusionsproteiner

Country Status (10)

Country Link
US (2) US5817308A (pt)
EP (1) EP0741788B1 (pt)
JP (2) JPH09509316A (pt)
AT (1) ATE288494T1 (pt)
CA (1) CA2182977A1 (pt)
DE (1) DE69533979T8 (pt)
DK (1) DK0741788T3 (pt)
ES (1) ES2233940T3 (pt)
PT (1) PT741788E (pt)
WO (1) WO1995021926A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817308A (en) * 1994-02-14 1998-10-06 University Of Rochester Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance
US6485726B1 (en) * 1995-01-17 2002-11-26 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
US5843462A (en) * 1995-11-30 1998-12-01 Regents Of The University Of Minnesota Diphtheria toxin epitopes
CA2315537A1 (en) 1997-12-16 1999-06-24 Regents Of The University Of Minnesota Methods to treat undesirable immune responses
KR100518958B1 (ko) * 1998-05-20 2005-10-06 추가이 세이야쿠 가부시키가이샤 신규한 유전자 클로닝 방법
US6884785B2 (en) * 1999-06-17 2005-04-26 The Scripps Research Institute Compositions and methods for the treatment or prevention of autoimmune diabetes
WO2001080880A2 (de) * 2000-04-22 2001-11-01 Stefan Barth Apoptotika
IL154284A0 (en) * 2000-09-25 2003-09-17 Nestle Sa Lactic acid bacteria capable of reducing an individual's tendency to develop allergic reactions
US8703146B2 (en) * 2001-04-20 2014-04-22 Institute For Systems Biology Toll-like receptor 5 ligands and methods of use
WO2002085933A1 (en) * 2001-04-20 2002-10-31 The Institute For Systems Biology Toll-like receptor 5 ligands and methods of use
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
US20120148585A1 (en) * 2001-05-01 2012-06-14 Andrew Saxon Fusion molecules and methods for treatment of immune diseases
US7744876B2 (en) 2002-04-09 2010-06-29 The Curators Of The University Of Missouri Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes
US8603472B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide
US8609091B2 (en) 2002-04-09 2013-12-17 The Curators Of The University Of Missouri Method for endocytic presentation of an immunosuppressive for the treatment of type 1 diabetes
US8603471B2 (en) * 2002-04-09 2013-12-10 The Curators Of The University Of Missouri Methods and compositions for preventing the onset of type 1 diabetes
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
CN101300355A (zh) * 2005-10-13 2008-11-05 威瑞克斯医药公司 包含丙型肝炎病毒多肽和用于引起免疫应答的Fc片段的嵌合抗原
EP2423222B2 (en) * 2007-01-30 2020-07-29 Epivax, Inc. Regulatory t cell epitopes, compositions and uses thereof
CN102405057B (zh) 2009-03-23 2016-05-25 那尼尔科斯治疗公司 用免疫刺激性Hiv Tat衍生物多肽治疗癌症
KR20150010716A (ko) 2012-03-23 2015-01-28 더 유니버시티 오브 퀸스랜드 면역조절제 및 이의 용도
CA2926221A1 (en) 2013-10-04 2015-04-09 Pin Pharma, Inc. Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2047244C (en) * 1989-02-24 2002-09-17 Zanetti Maurizio Genetically engineered immunoglobulins
US6248332B1 (en) * 1990-10-05 2001-06-19 Medarex, Inc. Targeted immunostimulation with bispecific reagents
GB9021679D0 (en) * 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
US5167956A (en) * 1991-02-11 1992-12-01 The United States Of America As Represented By The Department Of Health And Human Services Immunotoxin with in-vivo t cell suppressant activity
US5817308A (en) * 1994-02-14 1998-10-06 University Of Rochester Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance

Also Published As

Publication number Publication date
EP0741788A1 (en) 1996-11-13
DE69533979T8 (de) 2006-11-09
PT741788E (pt) 2005-05-31
ATE288494T1 (de) 2005-02-15
JP2008001709A (ja) 2008-01-10
CA2182977A1 (en) 1995-08-17
ES2233940T3 (es) 2005-06-16
DE69533979T2 (de) 2006-04-27
US20020048562A1 (en) 2002-04-25
JPH09509316A (ja) 1997-09-22
EP0741788B1 (en) 2005-02-02
US6838281B2 (en) 2005-01-04
DE69533979D1 (de) 2005-03-10
US5817308A (en) 1998-10-06
JP4214173B2 (ja) 2009-01-28
WO1995021926A1 (en) 1995-08-17

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