PT69988A - Procede de preparation de derives de fluorenes et fluoranthenes - Google Patents
Procede de preparation de derives de fluorenes et fluoranthenesInfo
- Publication number
- PT69988A PT69988A PT69988A PT6998879A PT69988A PT 69988 A PT69988 A PT 69988A PT 69988 A PT69988 A PT 69988A PT 6998879 A PT6998879 A PT 6998879A PT 69988 A PT69988 A PT 69988A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- radical
- hydrogen atom
- acyl
- fluorene
- Prior art date
Links
- NIHNNTQXNPWCJQ-UHFFFAOYSA-N fluorene Chemical compound C1=CC=C2CC3=CC=CC=C3C2=C1 NIHNNTQXNPWCJQ-UHFFFAOYSA-N 0.000 title 2
- GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthene Chemical class C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000002252 acyl group Chemical group 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 206010002660 Anoxia Diseases 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000006307 alkoxy benzyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000006177 alkyl benzyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002219 fluoranthenes Chemical class 0.000 abstract 1
- 150000002220 fluorenes Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- -1 halogenobenzyl Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7822352A FR2432025A1 (fr) | 1978-07-28 | 1978-07-28 | Derives d'imidazo et de pyrimido-pyrido-indoles, leur preparation et leur application en therapeutique |
| FR7822353A FR2432026A1 (fr) | 1978-07-28 | 1978-07-28 | Derives de fluorenes et de fluoranthenes et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT69988A true PT69988A (fr) | 1979-08-01 |
Family
ID=26220699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT69988A PT69988A (fr) | 1978-07-28 | 1979-07-26 | Procede de preparation de derives de fluorenes et fluoranthenes |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4277476A (https=) |
| EP (1) | EP0008249B1 (https=) |
| AT (1) | ATE165T1 (https=) |
| AU (1) | AU524307B2 (https=) |
| CA (1) | CA1107729A (https=) |
| DE (1) | DE2960689D1 (https=) |
| DK (1) | DK316279A (https=) |
| ES (1) | ES482889A1 (https=) |
| FI (1) | FI65250C (https=) |
| GR (1) | GR75070B (https=) |
| NO (1) | NO792476L (https=) |
| NZ (1) | NZ191141A (https=) |
| PT (1) | PT69988A (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2455044A1 (fr) * | 1979-04-26 | 1980-11-21 | Synthelabo | Pyrido-indoles et leur application en therapeutique |
| US4367230A (en) * | 1980-01-04 | 1983-01-04 | Tanabe Seiyaku Co., Ltd. | Novel triazafluoranthene compound and processes for preparing the same |
| US4428880A (en) | 1981-05-04 | 1984-01-31 | S.A. Omnichem | Azepino[4,5-d]indole derivatives and preparation thereof |
| FR2594070B1 (fr) * | 1985-12-19 | 1991-06-14 | Braas & Co Gmbh | Materiau composite deformable pour le recouvrement dans l'industrie du batiment |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| UA92317C2 (ru) | 2004-03-15 | 2010-10-25 | Пи-Ти-Си ТЕРАПЬЮТИКС, ИНК. | Производные карболина, пригодные для ингибирования развития кровеносных сосудов |
| US8076352B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
| US7767689B2 (en) | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
| CA2789262C (en) | 2005-04-28 | 2016-10-04 | Proteus Digital Health, Inc. | Pharma-informatics system |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| TR201908314T4 (tr) | 2009-02-20 | 2019-06-21 | 2 Bbb Medicines B V | Glutatyon bazlı ilaç dağıtım sistemi. |
| KR101909711B1 (ko) | 2009-05-06 | 2018-12-19 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2556574A (en) * | 1949-06-24 | 1951-06-12 | Allen & Hanburys Ltd | Indolopteridines and process for preparing same |
| US3108108A (en) * | 1959-09-25 | 1963-10-22 | Bayer Ag | Aza analogues of polynuclear o-quinones |
| US3122544A (en) * | 1962-11-13 | 1964-02-25 | American Home Prod | 4-amino-2-aryl-6h-indeno(2, 3-g)-pteridin-6-ones |
| US3470181A (en) * | 1967-10-23 | 1969-09-30 | American Home Prod | Fused 2-pyrimidinepropionic acid compounds,related compounds,and the process for their preparation |
| US3631046A (en) * | 1969-05-28 | 1971-12-28 | Sandoz Ag | Tetracyclic quinazolin-ones |
| BE759337A (fr) * | 1969-11-24 | 1971-05-24 | Lilly Co Eli | Benzimidazol (2,1-b)-quinazolin (6h) ones qui sont des immuno-depresseurs, et nouvelles benzimidazo (2,1-b) quinazolin-12-(6h) ones |
| US3963720A (en) * | 1972-10-27 | 1976-06-15 | Sandoz, Inc. | Tetracyclic imidazo [2,1-b] quinazolinone derivatives |
| CH601299A5 (en) * | 1973-11-07 | 1978-07-14 | Vni Khim Farmatsevtichesky I I | Pyrazino(1,2,3-ab)beta carbolines and homologues |
-
1979
- 1979-07-05 EP EP79400459A patent/EP0008249B1/fr not_active Expired
- 1979-07-05 DE DE7979400459T patent/DE2960689D1/de not_active Expired
- 1979-07-05 AT AT79400459T patent/ATE165T1/de not_active IP Right Cessation
- 1979-07-26 CA CA332,589A patent/CA1107729A/en not_active Expired
- 1979-07-26 DK DK316279A patent/DK316279A/da not_active Application Discontinuation
- 1979-07-26 US US06/060,857 patent/US4277476A/en not_active Expired - Lifetime
- 1979-07-26 AU AU49278/79A patent/AU524307B2/en not_active Ceased
- 1979-07-26 PT PT69988A patent/PT69988A/pt unknown
- 1979-07-26 NO NO792476A patent/NO792476L/no unknown
- 1979-07-27 ES ES482889A patent/ES482889A1/es not_active Expired
- 1979-07-27 NZ NZ191141A patent/NZ191141A/xx unknown
- 1979-07-27 FI FI792366A patent/FI65250C/fi not_active IP Right Cessation
-
1981
- 1981-01-05 GR GR59709A patent/GR75070B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES482889A1 (es) | 1980-04-16 |
| FI792366A7 (fi) | 1980-01-29 |
| EP0008249A3 (en) | 1980-05-14 |
| ATE165T1 (de) | 1981-09-15 |
| AU4927879A (en) | 1980-01-31 |
| CA1107729A (en) | 1981-08-25 |
| DK316279A (da) | 1980-01-29 |
| GR75070B (https=) | 1984-07-13 |
| AU524307B2 (en) | 1982-09-09 |
| NO792476L (no) | 1980-01-29 |
| FI65250C (fi) | 1984-04-10 |
| DE2960689D1 (en) | 1981-11-19 |
| US4277476A (en) | 1981-07-07 |
| EP0008249A2 (fr) | 1980-02-20 |
| FI65250B (fi) | 1983-12-30 |
| NZ191141A (en) | 1983-02-15 |
| EP0008249B1 (fr) | 1981-08-26 |
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