PT67626B - Process for preparing anti-inflammatory imidazoles and their corresponding sulfoxides and sulfones - Google Patents
Process for preparing anti-inflammatory imidazoles and their corresponding sulfoxides and sulfonesInfo
- Publication number
- PT67626B PT67626B PT67626A PT6762678A PT67626B PT 67626 B PT67626 B PT 67626B PT 67626 A PT67626 A PT 67626A PT 6762678 A PT6762678 A PT 6762678A PT 67626 B PT67626 B PT 67626B
- Authority
- PT
- Portugal
- Prior art keywords
- sulfones
- imidazoles
- inflammatory
- preparing anti
- corresponding sulfoxides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76722077A | 1977-02-09 | 1977-02-09 | |
| US05/865,832 US4159338A (en) | 1977-02-09 | 1978-01-05 | Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT67626A PT67626A (en) | 1978-03-01 |
| PT67626B true PT67626B (en) | 1979-07-17 |
Family
ID=27117879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT67626A PT67626B (en) | 1977-02-09 | 1978-02-06 | Process for preparing anti-inflammatory imidazoles and their corresponding sulfoxides and sulfones |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS53130664A (no) |
| AR (1) | AR219310A1 (no) |
| AT (1) | AT361470B (no) |
| AU (1) | AU517028B2 (no) |
| CA (1) | CA1105024A (no) |
| CH (1) | CH644108A5 (no) |
| DE (1) | DE2805167A1 (no) |
| DK (1) | DK16778A (no) |
| ES (1) | ES466794A1 (no) |
| FI (1) | FI69462C (no) |
| FR (1) | FR2380275A1 (no) |
| GB (1) | GB1564184A (no) |
| GR (1) | GR64142B (no) |
| HU (1) | HU178211B (no) |
| IE (1) | IE46187B1 (no) |
| IL (1) | IL53995A (no) |
| IT (1) | IT1092588B (no) |
| LU (1) | LU79024A1 (no) |
| MX (1) | MX5933E (no) |
| NL (1) | NL7801453A (no) |
| NO (1) | NO148265C (no) |
| NZ (1) | NZ186410A (no) |
| PH (1) | PH13852A (no) |
| PT (1) | PT67626B (no) |
| SE (1) | SE7801467L (no) |
| YU (1) | YU28878A (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2963572D1 (en) * | 1978-04-11 | 1982-10-21 | Ciba Geigy Ag | Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions |
| US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
| DK337779A (da) * | 1978-10-02 | 1980-04-03 | Du Pont | Fremgangsmaade til fremstilling af antiinflammatoriske 2-substituerede 1h-phenantro (9,10)-imidazoler |
| AT374198B (de) * | 1979-04-10 | 1984-03-26 | Ciba Geigy Ag | Verfahren zur herstellung neuer 2-substituierter mercaptoimidazolderivate, ihrer n-oxyde und ihrer salze |
| FI850995L (fi) * | 1984-03-16 | 1985-09-17 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya 3-merkapto-1,2,4-triazacykloalkadienderivat. |
| CA2295021A1 (en) * | 1997-06-30 | 1999-01-28 | Ortho-Mcneil Pharmaceutical, Inc. | 2-substituted imidazoles useful in the treatment of inflammatory diseases |
| DE10107683A1 (de) | 2001-02-19 | 2002-08-29 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2981739A (en) * | 1958-01-27 | 1961-04-25 | Diamond Alkali Co | Certain alpha-haloaldehyde addition products of ethylenethioureas and process |
| US3714179A (en) * | 1970-09-08 | 1973-01-30 | Searle & Co | 1-alkyl-2-furfurylthioimidazoles and congeners |
| JPS5343958B2 (no) * | 1972-07-29 | 1978-11-24 | ||
| SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
-
1978
- 1978-01-13 DK DK16778A patent/DK16778A/da not_active Application Discontinuation
- 1978-02-06 PT PT67626A patent/PT67626B/pt unknown
- 1978-02-07 CA CA296,606A patent/CA1105024A/en not_active Expired
- 1978-02-07 IT IT7820078A patent/IT1092588B/it active
- 1978-02-08 GB GB5098/78A patent/GB1564184A/en not_active Expired
- 1978-02-08 ES ES466794A patent/ES466794A1/es not_active Expired
- 1978-02-08 DE DE19782805167 patent/DE2805167A1/de not_active Withdrawn
- 1978-02-08 LU LU79024A patent/LU79024A1/xx unknown
- 1978-02-08 IL IL53995A patent/IL53995A/xx unknown
- 1978-02-08 IE IE279/78A patent/IE46187B1/en unknown
- 1978-02-08 NO NO780433A patent/NO148265C/no unknown
- 1978-02-08 FR FR7803518A patent/FR2380275A1/fr active Granted
- 1978-02-08 SE SE7801467A patent/SE7801467L/xx unknown
- 1978-02-08 AU AU33096/78A patent/AU517028B2/en not_active Expired
- 1978-02-08 YU YU00288/78A patent/YU28878A/xx unknown
- 1978-02-08 MX MX786829U patent/MX5933E/es unknown
- 1978-02-08 AT AT86978A patent/AT361470B/de not_active IP Right Cessation
- 1978-02-08 NZ NZ186410A patent/NZ186410A/xx unknown
- 1978-02-08 NL NL7801453A patent/NL7801453A/xx not_active Application Discontinuation
- 1978-02-09 HU HU78DU279A patent/HU178211B/hu unknown
- 1978-02-09 PH PH20771A patent/PH13852A/en unknown
- 1978-02-09 CH CH147478A patent/CH644108A5/de not_active IP Right Cessation
- 1978-02-09 FI FI780428A patent/FI69462C/fi not_active IP Right Cessation
- 1978-02-09 JP JP1304678A patent/JPS53130664A/ja active Pending
- 1978-02-09 GR GR55396A patent/GR64142B/el unknown
- 1978-02-09 AR AR271048A patent/AR219310A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| IT1092588B (it) | 1985-07-12 |
| NZ186410A (en) | 1979-12-11 |
| HU178211B (en) | 1982-03-28 |
| CH644108A5 (en) | 1984-07-13 |
| NO148265C (no) | 1983-09-07 |
| NO148265B (no) | 1983-05-30 |
| IE780279L (en) | 1978-08-09 |
| NL7801453A (nl) | 1978-08-11 |
| AT361470B (de) | 1981-03-10 |
| IE46187B1 (en) | 1983-03-23 |
| FI69462B (fi) | 1985-10-31 |
| ES466794A1 (es) | 1979-08-01 |
| DE2805167A1 (de) | 1978-08-10 |
| FR2380275A1 (fr) | 1978-09-08 |
| FR2380275B1 (no) | 1982-01-08 |
| GR64142B (en) | 1980-01-28 |
| AR219310A1 (es) | 1980-08-15 |
| ATA86978A (de) | 1980-08-15 |
| JPS53130664A (en) | 1978-11-14 |
| NO780433L (no) | 1978-08-10 |
| IT7820078A0 (it) | 1978-02-07 |
| SE7801467L (sv) | 1978-08-10 |
| AU3309678A (en) | 1979-08-16 |
| LU79024A1 (fr) | 1979-05-25 |
| IL53995A0 (en) | 1978-04-30 |
| DK16778A (da) | 1978-08-10 |
| FI780428A (fi) | 1978-08-10 |
| FI69462C (fi) | 1986-02-10 |
| CA1105024A (en) | 1981-07-14 |
| PT67626A (en) | 1978-03-01 |
| YU28878A (en) | 1983-01-21 |
| PH13852A (en) | 1980-10-22 |
| MX5933E (es) | 1984-08-30 |
| AU517028B2 (en) | 1981-07-02 |
| IL53995A (en) | 1982-02-28 |
| GB1564184A (en) | 1980-04-02 |
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