PT3983387T - Derivados de sulfonilurea e seus usos - Google Patents
Derivados de sulfonilurea e seus usosInfo
- Publication number
- PT3983387T PT3983387T PT207337064T PT20733706T PT3983387T PT 3983387 T PT3983387 T PT 3983387T PT 207337064 T PT207337064 T PT 207337064T PT 20733706 T PT20733706 T PT 20733706T PT 3983387 T PT3983387 T PT 3983387T
- Authority
- PT
- Portugal
- Prior art keywords
- sulfonylurea derivatives
- sulfonylurea
- derivatives
- Prior art date
Links
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860663P | 2019-06-12 | 2019-06-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3983387T true PT3983387T (pt) | 2024-07-10 |
Family
ID=71108563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT207337064T PT3983387T (pt) | 2019-06-12 | 2020-06-11 | Derivados de sulfonilurea e seus usos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US12054461B2 (enExample) |
| EP (1) | EP3983387B1 (enExample) |
| JP (1) | JP7682813B2 (enExample) |
| CN (1) | CN114641466B (enExample) |
| DK (1) | DK3983387T3 (enExample) |
| ES (1) | ES2983661T3 (enExample) |
| FI (1) | FI3983387T3 (enExample) |
| HR (1) | HRP20240896T1 (enExample) |
| HU (1) | HUE067378T2 (enExample) |
| LT (1) | LT3983387T (enExample) |
| PL (1) | PL3983387T3 (enExample) |
| PT (1) | PT3983387T (enExample) |
| RS (1) | RS65711B1 (enExample) |
| SI (1) | SI3983387T1 (enExample) |
| SM (1) | SMT202400291T1 (enExample) |
| WO (1) | WO2020249667A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| CN114641466B (zh) | 2019-06-12 | 2025-09-30 | 诺瑟拉有限公司 | 磺酰脲衍生物及其用途 |
| KR102802013B1 (ko) * | 2021-02-03 | 2025-05-07 | 환인제약 주식회사 | 알츠하이머병 치료를 위한 nlrp3 인플라마좀 소분자 억제제 |
Family Cites Families (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2110689A (en) | 1981-12-03 | 1983-06-22 | Sandoz Ltd | Herbicidal heterocyclic aminosulfonyl ureas and isoureas |
| CH649081A5 (de) | 1982-01-12 | 1985-04-30 | Ciba Geigy Ag | Triaza-verbindungen. |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JPS60214785A (ja) * | 1984-03-27 | 1985-10-28 | Nissan Chem Ind Ltd | ピラゾ−ルスルホニルウレア誘導体、および植物生長調節剤または除草剤 |
| US5214206A (en) | 1990-11-07 | 1993-05-25 | Warner-Lambert Company | Aminosulfonyl urea acat inhibitors |
| WO1993004045A1 (en) | 1991-08-19 | 1993-03-04 | E.I. Du Pont De Nemours And Company | Angiotensin ii receptor blocking imidazolinone derivatives |
| AU2494792A (en) | 1991-08-19 | 1993-03-16 | E.I. Du Pont De Nemours And Company | Angiotensin ii receptor blocking imidazolinone derivatives |
| NZ247440A (en) | 1992-05-06 | 1995-04-27 | Squibb & Sons Inc | Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof |
| DE4217719A1 (de) * | 1992-05-29 | 1993-12-02 | Bayer Ag | Zweifach heterocyclisch substituierte Sulfonylamino(thio)carbonylverbindungen |
| DE4302702A1 (de) | 1993-02-01 | 1994-08-04 | Bayer Ag | Arylaminosulfonylharnstoffe |
| DE4302701A1 (de) | 1993-02-01 | 1994-08-04 | Bayer Ag | Arylaminosulfonylharnstoffe |
| JP3355237B2 (ja) * | 1993-10-15 | 2002-12-09 | 呉羽化学工業株式会社 | Ｎ−（置換アミノ）ピロール誘導体、その製造方法及び除草剤 |
| JPH0827147A (ja) * | 1994-07-20 | 1996-01-30 | Kureha Chem Ind Co Ltd | Ｎ−（置換アミノ）イミド誘導体、その製造方法及び除草剤 |
| JPH09132574A (ja) | 1995-11-09 | 1997-05-20 | Nissan Chem Ind Ltd | フルオロプロピルチアゾリン誘導体の製造法 |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| US6028201A (en) | 1996-01-30 | 2000-02-22 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| WO1998000408A1 (en) | 1996-07-02 | 1998-01-08 | Novartis Ag | N-phenylimino heterocyclic derivatives and their use as herbicides |
| JPH1029990A (ja) | 1996-07-12 | 1998-02-03 | Kureha Chem Ind Co Ltd | １−（置換アミノ）イミダゾール誘導体、その製造方法及び除草剤 |
| DE19651037A1 (de) | 1996-12-09 | 1998-06-10 | Bayer Ag | Substituierte Thienyl(amino)sulfonyl(thio)harnstoffe |
| AU723895B2 (en) | 1997-01-29 | 2000-09-07 | Pfizer Inc. | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| IT1290062B1 (it) | 1997-03-13 | 1998-10-19 | Isagro Ricerca Srl | Amminosolfoniluree ad attivita' erbicida |
| GB9909409D0 (en) | 1999-04-24 | 1999-06-23 | Zeneca Ltd | Chemical compounds |
| DE19937118A1 (de) | 1999-08-06 | 2001-02-08 | Bayer Ag | Substituierte Thienyl(amino)sulfonylharnstoffe |
| JP4112127B2 (ja) | 1999-08-31 | 2008-07-02 | 株式会社リコー | 感熱記録材料 |
| AU7447500A (en) | 1999-09-30 | 2001-04-30 | Mitsubishi Chemical Corporation | Acylsulfonamide derivatives |
| US6593356B2 (en) | 1999-10-20 | 2003-07-15 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
| EP1281399A3 (en) | 2001-08-01 | 2004-02-11 | Warner-Lambert Company | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production |
| WO2003029226A1 (en) | 2001-09-26 | 2003-04-10 | Basf Aktiengesellschaft | Heterocyclyl substituted phenoxyalkyl-, phenylthioalkyl-, phenylaminoalkyl- and phenylalkyl-sulfamoylcarboxamides |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| AU2005325676A1 (en) | 2004-12-23 | 2006-08-03 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| WO2009086303A2 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| CN104245696A (zh) | 2012-02-07 | 2014-12-24 | 凯诺斯医药公司 | 作为1型二酰基甘油o-酰基转移酶的抑制剂的化合物 |
| CN103288750A (zh) | 2013-03-04 | 2013-09-11 | 盐城工学院 | 新型氨基磺酰脲类化合物 |
| US9410217B2 (en) | 2014-02-18 | 2016-08-09 | Renmatix, Inc. | Method of reducing a fermentation and/or enzyme inhibitor in a saccharide-containing composition |
| KR102727059B1 (ko) | 2015-02-16 | 2024-11-05 | 더 유니버서티 어브 퀸슬랜드 | 설포닐우레아와 관련 화합물 및 그 용도 |
| CN109071454B (zh) * | 2016-02-16 | 2023-02-17 | 昆士兰大学 | 磺酰脲和相关化合物及其用途 |
| WO2017189663A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| US10080741B2 (en) | 2016-04-26 | 2018-09-25 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as FXR agonists and methods of use thereof |
| WO2017189651A1 (en) | 2016-04-26 | 2017-11-02 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| US10144729B2 (en) | 2016-05-18 | 2018-12-04 | Enanta Pharmaceuticals, Inc. | Isoxazole analogs as FXR agonists and methods of use thereof |
| WO2017201152A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | Isoxazole derivatives as fxr agonists and methods of use thereof |
| WO2017201155A1 (en) | 2016-05-18 | 2017-11-23 | Enanta Pharmaceuticals, Inc. | lSOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF |
| EP3272739A1 (en) | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| RS65492B1 (sr) | 2017-07-24 | 2024-05-31 | Novartis Ag | Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću nlrp |
| EP3668861A1 (en) * | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| US11518739B2 (en) | 2017-08-15 | 2022-12-06 | Inflazome Limited | Sulfonamide carboxamide compounds |
| MX2020001776A (es) | 2017-08-15 | 2020-03-24 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3. |
| JP2020531448A (ja) | 2017-08-15 | 2020-11-05 | インフレイゾーム リミテッド | 新規なスルホンアミドカルボキサミド化合物 |
| WO2019034693A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
| EP3668862A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| US11542255B2 (en) | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| GB201902327D0 (en) * | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
| US12187702B2 (en) * | 2018-08-15 | 2025-01-07 | Inflazome Limited | Sulfonamideurea compounds |
| CN114641466B (zh) | 2019-06-12 | 2025-09-30 | 诺瑟拉有限公司 | 磺酰脲衍生物及其用途 |
| CN114761383A (zh) | 2019-06-12 | 2022-07-15 | 诺瑟拉有限公司 | 磺酰胺衍生物及其用途 |
| CN114222739B (zh) | 2019-06-12 | 2025-02-11 | 诺瑟拉有限公司 | 磺酰脲衍生物及其用途 |
| CN116783184A (zh) | 2020-09-04 | 2023-09-19 | 诺瑟拉有限公司 | 含有烷基-氧杂环烷基部分的氨磺酰基脲衍生物及其用途 |
-
2020
- 2020-06-11 CN CN202080057162.2A patent/CN114641466B/zh active Active
- 2020-06-11 SM SM20240291T patent/SMT202400291T1/it unknown
- 2020-06-11 RS RS20240765A patent/RS65711B1/sr unknown
- 2020-06-11 PL PL20733706.4T patent/PL3983387T3/pl unknown
- 2020-06-11 HU HUE20733706A patent/HUE067378T2/hu unknown
- 2020-06-11 HR HRP20240896TT patent/HRP20240896T1/hr unknown
- 2020-06-11 SI SI202030459T patent/SI3983387T1/sl unknown
- 2020-06-11 EP EP20733706.4A patent/EP3983387B1/en active Active
- 2020-06-11 WO PCT/EP2020/066191 patent/WO2020249667A1/en not_active Ceased
- 2020-06-11 FI FIEP20733706.4T patent/FI3983387T3/fi active
- 2020-06-11 ES ES20733706T patent/ES2983661T3/es active Active
- 2020-06-11 US US17/618,184 patent/US12054461B2/en active Active
- 2020-06-11 PT PT207337064T patent/PT3983387T/pt unknown
- 2020-06-11 DK DK20733706.4T patent/DK3983387T3/da active
- 2020-06-11 LT LTEPPCT/EP2020/066191T patent/LT3983387T/lt unknown
- 2020-06-11 JP JP2021573382A patent/JP7682813B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7682813B2 (ja) | 2025-05-26 |
| CN114641466B (zh) | 2025-09-30 |
| US12054461B2 (en) | 2024-08-06 |
| FI3983387T3 (fi) | 2024-07-09 |
| SI3983387T1 (sl) | 2024-09-30 |
| HUE067378T2 (hu) | 2024-10-28 |
| WO2020249667A1 (en) | 2020-12-17 |
| EP3983387A1 (en) | 2022-04-20 |
| SMT202400291T1 (it) | 2024-09-16 |
| JP2022535956A (ja) | 2022-08-10 |
| ES2983661T3 (es) | 2024-10-24 |
| EP3983387B1 (en) | 2024-04-24 |
| DK3983387T3 (da) | 2024-07-15 |
| LT3983387T (lt) | 2024-07-25 |
| HRP20240896T1 (hr) | 2024-10-11 |
| CN114641466A (zh) | 2022-06-17 |
| RS65711B1 (sr) | 2024-08-30 |
| PL3983387T3 (pl) | 2024-08-19 |
| US20220227715A1 (en) | 2022-07-21 |
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