PT3723815T - Ligandos psma para imagiologia e endorradioterapia - Google Patents

Ligandos psma para imagiologia e endorradioterapia

Info

Publication number
PT3723815T
PT3723815T PT188122154T PT18812215T PT3723815T PT 3723815 T PT3723815 T PT 3723815T PT 188122154 T PT188122154 T PT 188122154T PT 18812215 T PT18812215 T PT 18812215T PT 3723815 T PT3723815 T PT 3723815T
Authority
PT
Portugal
Prior art keywords
endoradiotherapy
imaging
psma ligands
psma
ligands
Prior art date
Application number
PT188122154T
Other languages
English (en)
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Publication of PT3723815T publication Critical patent/PT3723815T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nuclear Medicine (AREA)
  • Peptides Or Proteins (AREA)
PT188122154T 2017-12-11 2018-12-11 Ligandos psma para imagiologia e endorradioterapia PT3723815T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17206510 2017-12-11

Publications (1)

Publication Number Publication Date
PT3723815T true PT3723815T (pt) 2022-05-30

Family

ID=60654872

Family Applications (1)

Application Number Title Priority Date Filing Date
PT188122154T PT3723815T (pt) 2017-12-11 2018-12-11 Ligandos psma para imagiologia e endorradioterapia

Country Status (30)

Country Link
US (2) US11497819B2 (pt)
EP (2) EP4008359A1 (pt)
JP (2) JP7317375B2 (pt)
KR (1) KR20200097690A (pt)
CN (2) CN111182927B (pt)
AU (1) AU2018382479A1 (pt)
BR (1) BR112020011727A2 (pt)
CA (1) CA3078104A1 (pt)
CL (1) CL2020001542A1 (pt)
CR (1) CR20200241A (pt)
CU (1) CU24677B1 (pt)
DK (1) DK3723815T3 (pt)
EC (1) ECSP20029142A (pt)
ES (1) ES2914832T3 (pt)
HR (1) HRP20220764T1 (pt)
HU (1) HUE059083T2 (pt)
IL (1) IL274072A (pt)
JO (1) JOP20200135A1 (pt)
LT (1) LT3723815T (pt)
MX (2) MX2020005430A (pt)
PE (1) PE20210456A1 (pt)
PL (1) PL3723815T3 (pt)
PT (1) PT3723815T (pt)
RS (1) RS63279B1 (pt)
SG (1) SG11202002965WA (pt)
SI (1) SI3723815T1 (pt)
TN (1) TN2020000072A1 (pt)
UA (1) UA126413C2 (pt)
WO (1) WO2019115547A1 (pt)
ZA (1) ZA202003472B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7317375B2 (ja) 2017-12-11 2023-07-31 テクニシェ ユニバーシタット ミュンヘン 画像化および内部放射線療法のためのpsmaリガンド
KR20220024595A (ko) 2019-06-21 2022-03-03 프로빈셜 헬스 서비시즈 오쏘리티 전립선-특이적 막 항원을 표적으로 하는 방사성표지 화합물
CN112321673B (zh) * 2020-11-04 2022-09-20 北京市肿瘤防治研究所 一种前列腺特异性膜抗原靶向抑制剂及应用和探针
CN113354707A (zh) * 2021-06-07 2021-09-07 苏州思萃同位素技术研究所有限公司 一种针对前列腺癌的三功能诊疗一体化药物前体的合成方法及其产品
WO2023173074A2 (en) * 2022-03-10 2023-09-14 The Research Foundation For The State University Of New York Immunostimulant-cytotoxic conjugate composition and methods for cancer treatment
CN115010629B (zh) * 2022-06-07 2024-02-23 西南医科大学附属医院 前列腺特异性膜抗原抑制剂、其核素标记物及制法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006125048A2 (en) 2005-05-16 2006-11-23 Gilead Sciences, Inc. Hiv-integrase inhibitor compounds
EP4089074A1 (en) * 2008-08-01 2022-11-16 The Johns Hopkins University Psma-binding agents and uses thereof
WO2010135431A2 (en) * 2009-05-19 2010-11-25 The Regents Of The University Of California Compositions, devices, and methods related to prostate-specific membrane antigen
GEP20237496B (en) * 2013-10-18 2023-04-10 Deutsches Krebsforsch Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
JP6749249B2 (ja) * 2014-05-06 2020-09-02 ザ ジョンズ ホプキンズ ユニヴァーシティー Psmaを標的としたイメージング及び放射線治療のための金属/放射性金属標識psma阻害剤
US10688200B2 (en) 2015-12-31 2020-06-23 Five Eleven Pharma Inc. Urea-based prostate specific membrane antigen (PSMA) inhibitors for imaging and therapy
EP3925952B1 (en) * 2016-03-22 2023-11-29 The Johns Hopkins University Prostate-specific membrane antigen targeted high-affinity agents for endoradiotherapy of prostate cancer
HUE058247T2 (hu) 2017-12-11 2022-07-28 Helsinn Healthcare Sa (R)-3-(1-(2,3-Diklór-4-(pirazin-2-il)fenil)-2,2,2-trifluoretil)-1-metil-1-(1-metilpiperidin-4-il)karbamid fumarát sója, elõállítási eljárásai és alkalmazásai
JP7317375B2 (ja) 2017-12-11 2023-07-31 テクニシェ ユニバーシタット ミュンヘン 画像化および内部放射線療法のためのpsmaリガンド
TW201930265A (zh) 2017-12-11 2019-08-01 西班牙商阿爾米雷爾有限公司 作為acc抑制劑的吡咯衍生物

Also Published As

Publication number Publication date
US20230122957A1 (en) 2023-04-20
JOP20200135A1 (ar) 2020-06-02
CU24677B1 (es) 2023-09-07
CR20200241A (es) 2020-09-21
LT3723815T (lt) 2022-07-25
WO2019115547A1 (en) 2019-06-20
CN111182927B (zh) 2023-07-21
US11497819B2 (en) 2022-11-15
BR112020011727A2 (pt) 2020-11-17
JP2021505532A (ja) 2021-02-18
TN2020000072A1 (en) 2022-01-06
CU20200052A7 (es) 2021-03-11
AU2018382479A1 (en) 2020-04-16
US20200297876A1 (en) 2020-09-24
IL274072A (en) 2020-06-30
HRP20220764T1 (hr) 2022-09-16
EP3723815A1 (en) 2020-10-21
ES2914832T3 (es) 2022-06-16
UA126413C2 (uk) 2022-09-28
PL3723815T3 (pl) 2022-07-18
KR20200097690A (ko) 2020-08-19
MX2020005430A (es) 2020-08-27
RU2020116158A (ru) 2022-01-13
SG11202002965WA (en) 2020-04-29
ZA202003472B (en) 2022-06-29
MX2023005053A (es) 2023-05-17
CA3078104A1 (en) 2019-06-20
ECSP20029142A (es) 2020-09-30
EP4008359A1 (en) 2022-06-08
CN111182927A (zh) 2020-05-19
SI3723815T1 (sl) 2022-07-29
CL2020001542A1 (es) 2020-10-02
PE20210456A1 (es) 2021-03-08
EP3723815B1 (en) 2022-04-20
RS63279B1 (sr) 2022-06-30
CN116617421A (zh) 2023-08-22
HUE059083T2 (hu) 2022-10-28
DK3723815T3 (da) 2022-07-11
JP7317375B2 (ja) 2023-07-31
JP2023139063A (ja) 2023-10-03

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