SG11202002965WA - Psma ligands for imaging and endoradiotherapy - Google Patents

Psma ligands for imaging and endoradiotherapy

Info

Publication number
SG11202002965WA
SG11202002965WA SG11202002965WA SG11202002965WA SG11202002965WA SG 11202002965W A SG11202002965W A SG 11202002965WA SG 11202002965W A SG11202002965W A SG 11202002965WA SG 11202002965W A SG11202002965W A SG 11202002965WA SG 11202002965W A SG11202002965W A SG 11202002965WA
Authority
SG
Singapore
Prior art keywords
endoradiotherapy
imaging
psma ligands
psma
ligands
Prior art date
Application number
SG11202002965WA
Inventor
Hans-Jürgen Wester
Alexander Schmidt
Mara Parzinger
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Publication of SG11202002965WA publication Critical patent/SG11202002965WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nuclear Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202002965WA 2017-12-11 2018-12-11 Psma ligands for imaging and endoradiotherapy SG11202002965WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17206510 2017-12-11
PCT/EP2018/084399 WO2019115547A1 (en) 2017-12-11 2018-12-11 Psma ligands for imaging and endoradiotherapy

Publications (1)

Publication Number Publication Date
SG11202002965WA true SG11202002965WA (en) 2020-04-29

Family

ID=60654872

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002965WA SG11202002965WA (en) 2017-12-11 2018-12-11 Psma ligands for imaging and endoradiotherapy

Country Status (30)

Country Link
US (2) US11497819B2 (en)
EP (2) EP3723815B1 (en)
JP (1) JP7317375B2 (en)
KR (1) KR20200097690A (en)
CN (2) CN111182927B (en)
AU (1) AU2018382479A1 (en)
BR (1) BR112020011727A2 (en)
CA (1) CA3078104A1 (en)
CL (1) CL2020001542A1 (en)
CR (1) CR20200241A (en)
CU (1) CU24677B1 (en)
DK (2) DK3723815T3 (en)
EC (1) ECSP20029142A (en)
ES (1) ES2914832T3 (en)
HR (1) HRP20220764T1 (en)
HU (1) HUE059083T2 (en)
IL (2) IL274072B1 (en)
JO (1) JOP20200135A1 (en)
LT (1) LT3723815T (en)
MX (2) MX2020005430A (en)
PE (1) PE20210456A1 (en)
PL (1) PL3723815T3 (en)
PT (1) PT3723815T (en)
RS (1) RS63279B1 (en)
SG (1) SG11202002965WA (en)
SI (1) SI3723815T1 (en)
TN (1) TN2020000072A1 (en)
UA (1) UA126413C2 (en)
WO (1) WO2019115547A1 (en)
ZA (1) ZA202003472B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA126413C2 (en) 2017-12-11 2022-09-28 Техніше Універзітет Мюнхен Psma ligands for imaging and endoradiotherapy
PL3917626T3 (en) * 2019-01-30 2023-11-27 Technische Universität München Psma binding dual mode radiotracer and therapeutic
IL303420A (en) * 2019-01-30 2023-08-01 Univ Muenchen Tech Cancer diagnostic imaging agents
WO2020252598A1 (en) 2019-06-21 2020-12-24 Provincial Health Services Authority Radiolabeled compounds targeting the prostate-specific membrane antigen
CN112321673B (en) * 2020-11-04 2022-09-20 北京市肿瘤防治研究所 Prostate specific membrane antigen targeted inhibitor, application and probe
CN113354707A (en) * 2021-06-07 2021-09-07 苏州思萃同位素技术研究所有限公司 Synthetic method of three-function diagnosis and treatment integrated prodrug for prostate cancer and product thereof
WO2023173074A2 (en) * 2022-03-10 2023-09-14 The Research Foundation For The State University Of New York Immunostimulant-cytotoxic conjugate composition and methods for cancer treatment
CN115010629B (en) * 2022-06-07 2024-02-23 西南医科大学附属医院 Prostate specific membrane antigen inhibitor, nuclide marker, preparation method and application

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR057023A1 (en) 2005-05-16 2007-11-14 Gilead Sciences Inc HETEROCICLICAL COMPOUNDS WITH HIV-INTEGRASA INHIBITING PROPERTIES
CN107382846B (en) * 2008-08-01 2021-07-06 约翰.霍普金斯大学 PSMA-binding agents and uses thereof
WO2010135431A2 (en) * 2009-05-19 2010-11-25 The Regents Of The University Of California Compositions, devices, and methods related to prostate-specific membrane antigen
DE202014011600U1 (en) * 2013-10-18 2023-05-31 Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts Labeled prostate-specific membrane antigen (PSMA) inhibitors, their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
US10683272B2 (en) * 2014-05-06 2020-06-16 The Johns Hopkins University Metal/radiometal-labeled PSMA inhibitors for PSMA-targeted imaging and radiotherapy
US10688200B2 (en) 2015-12-31 2020-06-23 Five Eleven Pharma Inc. Urea-based prostate specific membrane antigen (PSMA) inhibitors for imaging and therapy
CN114716387A (en) * 2016-03-22 2022-07-08 约翰霍普金斯大学 Prostate specific membrane antigen targeted high affinity agents for intracavitary radiotherapy of prostate cancer
TW201930265A (en) 2017-12-11 2019-08-01 西班牙商阿爾米雷爾有限公司 Pyrrole derivatives as ACC inhibitors
BR112020010803A2 (en) 2017-12-11 2020-11-10 Helsinn Healthcare Sa salt, (r) -3- (1- (2,3-dichloro-4- (pyrazin-2-yl) phenyl) -2,2,2-trifluoroethyl) -1-methyl-1- (1-methylpiperidin- 4-il) crystalline urea, medication product, composition, method for preparing salt and uses of salt
UA126413C2 (en) 2017-12-11 2022-09-28 Техніше Універзітет Мюнхен Psma ligands for imaging and endoradiotherapy

Also Published As

Publication number Publication date
IL274072B1 (en) 2024-07-01
IL313103A (en) 2024-07-01
EP4008359A1 (en) 2022-06-08
HRP20220764T1 (en) 2022-09-16
TN2020000072A1 (en) 2022-01-06
EP3723815A1 (en) 2020-10-21
US20230122957A1 (en) 2023-04-20
PE20210456A1 (en) 2021-03-08
CR20200241A (en) 2020-09-21
CA3078104A1 (en) 2019-06-20
CU24677B1 (en) 2023-09-07
CL2020001542A1 (en) 2020-10-02
US20200297876A1 (en) 2020-09-24
ZA202003472B (en) 2022-06-29
LT3723815T (en) 2022-07-25
SI3723815T1 (en) 2022-07-29
UA126413C2 (en) 2022-09-28
IL274072A (en) 2020-06-30
CU20200052A7 (en) 2021-03-11
CN111182927A (en) 2020-05-19
RU2020116158A (en) 2022-01-13
WO2019115547A1 (en) 2019-06-20
MX2020005430A (en) 2020-08-27
DK3723815T3 (en) 2022-07-11
CN116617421A (en) 2023-08-22
EP3723815B1 (en) 2022-04-20
US11497819B2 (en) 2022-11-15
MX2023005053A (en) 2023-05-17
DK4008359T3 (en) 2024-10-14
JOP20200135A1 (en) 2020-06-02
HUE059083T2 (en) 2022-10-28
JP2021505532A (en) 2021-02-18
CN111182927B (en) 2023-07-21
JP7317375B2 (en) 2023-07-31
ECSP20029142A (en) 2020-09-30
KR20200097690A (en) 2020-08-19
ES2914832T3 (en) 2022-06-16
PT3723815T (en) 2022-05-30
JP2023139063A (en) 2023-10-03
AU2018382479A1 (en) 2020-04-16
BR112020011727A2 (en) 2020-11-17
EP4008359B1 (en) 2024-09-11
RS63279B1 (en) 2022-06-30
PL3723815T3 (en) 2022-07-18

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