PT3692040T - Compostos químicos - Google Patents
Compostos químicosInfo
- Publication number
- PT3692040T PT3692040T PT187958095T PT18795809T PT3692040T PT 3692040 T PT3692040 T PT 3692040T PT 187958095 T PT187958095 T PT 187958095T PT 18795809 T PT18795809 T PT 18795809T PT 3692040 T PT3692040 T PT 3692040T
- Authority
- PT
- Portugal
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762568633P | 2017-10-05 | 2017-10-05 | |
| US201762570509P | 2017-10-10 | 2017-10-10 | |
| US201862681146P | 2018-06-06 | 2018-06-06 | |
| US201862683859P | 2018-06-12 | 2018-06-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3692040T true PT3692040T (pt) | 2023-04-03 |
Family
ID=64049476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT187958095T PT3692040T (pt) | 2017-10-05 | 2018-10-05 | Compostos químicos |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US20200255428A1 (pt) |
| EP (2) | EP4180431A1 (pt) |
| JP (1) | JP7248665B2 (pt) |
| CN (2) | CN116942663A (pt) |
| AU (2) | AU2018344926A1 (pt) |
| BR (1) | BR112020006456A2 (pt) |
| CA (1) | CA3078312A1 (pt) |
| CL (1) | CL2020000912A1 (pt) |
| CO (1) | CO2020004202A2 (pt) |
| DK (1) | DK3692040T3 (pt) |
| ES (1) | ES2940263T3 (pt) |
| FI (1) | FI3692040T3 (pt) |
| HR (1) | HRP20230274T1 (pt) |
| HU (1) | HUE061380T2 (pt) |
| IL (1) | IL273769A (pt) |
| LT (1) | LT3692040T (pt) |
| MX (1) | MX2020003382A (pt) |
| PH (1) | PH12020550145A1 (pt) |
| PL (1) | PL3692040T3 (pt) |
| PT (1) | PT3692040T (pt) |
| RS (1) | RS64043B1 (pt) |
| SG (2) | SG11202002771XA (pt) |
| SI (1) | SI3692040T1 (pt) |
| WO (1) | WO2019069293A1 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10738035B2 (en) | 2015-05-13 | 2020-08-11 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| PL3426245T3 (pl) | 2016-03-07 | 2023-05-22 | Enanta Pharmaceuticals, Inc. | Środki przeciwwirusowe zapalenia wątroby typu b |
| SG11202001685TA (en) | 2017-08-28 | 2020-03-30 | Enanta Pharm Inc | Hepatitis b antiviral agents |
| WO2019143902A2 (en) | 2018-01-22 | 2019-07-25 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| US10729688B2 (en) | 2018-03-29 | 2020-08-04 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| WO2019246427A1 (en) * | 2018-06-22 | 2019-12-26 | Arbutus Biopharma Corporation | Crystalline forms of pyridinone-containing tricyclic compounds and methods of preparing and using same |
| CA3113235A1 (en) | 2018-09-21 | 2020-03-26 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| US11447498B2 (en) | 2018-09-30 | 2022-09-20 | Sunshine Lake Pharma Co., Ltd. | Fused tetracyclic compounds and uses thereof in medicine |
| WO2020106816A1 (en) | 2018-11-21 | 2020-05-28 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| CN111217811B (zh) * | 2018-11-26 | 2024-01-16 | 广东东阳光药业股份有限公司 | 稠合三环类化合物及其在药物中的应用 |
| TW202104214A (zh) | 2019-04-05 | 2021-02-01 | 英商葛蘭素史密斯克藍智慧財產發展有限公司 | 化合物 |
| WO2020247444A1 (en) | 2019-06-03 | 2020-12-10 | Enanta Pharmaceuticals, Inc, | Hepatitis b antiviral agents |
| US11760755B2 (en) | 2019-06-04 | 2023-09-19 | Enanta Pharmaceuticals, Inc. | Hepatitis B antiviral agents |
| US11472808B2 (en) | 2019-06-04 | 2022-10-18 | Enanta Pharmaceuticals, Inc. | Substituted pyrrolo[1,2-c]pyrimidines as hepatitis B antiviral agents |
| US11738019B2 (en) | 2019-07-11 | 2023-08-29 | Enanta Pharmaceuticals, Inc. | Substituted heterocycles as antiviral agents |
| US11236108B2 (en) | 2019-09-17 | 2022-02-01 | Enanta Pharmaceuticals, Inc. | Functionalized heterocycles as antiviral agents |
| US11802125B2 (en) | 2020-03-16 | 2023-10-31 | Enanta Pharmaceuticals, Inc. | Functionalized heterocyclic compounds as antiviral agents |
| CN113173911A (zh) * | 2021-04-20 | 2021-07-27 | 梯尔希（南京）药物研发有限公司 | 吡虫啉代谢物5-羟基吡虫啉的合成方法 |
| CN118660704A (zh) | 2022-01-28 | 2024-09-17 | 葛兰素史密斯克莱知识产权发展有限公司 | 用于治疗乙型肝炎病毒感染的组合疗法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3099685B1 (en) * | 2014-01-30 | 2018-04-18 | F.Hoffmann-La Roche Ag | Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection |
| JP6568106B2 (ja) | 2014-05-13 | 2019-08-28 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｂ型肝炎ウイルス感染症の治療及び予防のための新規ジヒドロキノリジノン類 |
| US9637485B2 (en) * | 2014-11-03 | 2017-05-02 | Hoffmann-La Roche Inc. | 6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection |
| WO2016128335A1 (en) * | 2015-02-11 | 2016-08-18 | F. Hoffmann-La Roche Ag | Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection |
| WO2017108630A1 (en) * | 2015-12-21 | 2017-06-29 | F. Hoffmann-La Roche Ag | Combination therapy of an hbsag inhibitor and an hbv capsid assembly inhibitor |
| TW201811788A (zh) * | 2016-09-09 | 2018-04-01 | 瑞士商諾華公司 | 作為抗病毒劑之多環吡啶酮化合物 |
| CN110114071B (zh) | 2016-11-07 | 2023-07-04 | 爱彼特生物制药公司 | 含有取代的吡啶酮的三环化合物以及使用其的方法 |
| CN109369640B (zh) * | 2017-01-13 | 2020-03-27 | 苏州爱科百发生物医药技术有限公司 | 一种二氢异喹啉类化合物的制备方法 |
| CN108727378A (zh) | 2017-04-19 | 2018-11-02 | 银杏树药业(苏州)有限公司 | 新型异喹啉类化合物及其医药用途 |
-
2018
- 2018-10-05 SG SG11202002771XA patent/SG11202002771XA/en unknown
- 2018-10-05 EP EP22214773.8A patent/EP4180431A1/en active Pending
- 2018-10-05 HR HRP20230274TT patent/HRP20230274T1/hr unknown
- 2018-10-05 PT PT187958095T patent/PT3692040T/pt unknown
- 2018-10-05 HU HUE18795809A patent/HUE061380T2/hu unknown
- 2018-10-05 BR BR112020006456-4A patent/BR112020006456A2/pt unknown
- 2018-10-05 US US16/753,645 patent/US20200255428A1/en not_active Abandoned
- 2018-10-05 WO PCT/IB2018/057767 patent/WO2019069293A1/en unknown
- 2018-10-05 JP JP2020519410A patent/JP7248665B2/ja active Active
- 2018-10-05 DK DK18795809.5T patent/DK3692040T3/da active
- 2018-10-05 RS RS20230207A patent/RS64043B1/sr unknown
- 2018-10-05 ES ES18795809T patent/ES2940263T3/es active Active
- 2018-10-05 PL PL18795809.5T patent/PL3692040T3/pl unknown
- 2018-10-05 CA CA3078312A patent/CA3078312A1/en active Pending
- 2018-10-05 FI FIEP18795809.5T patent/FI3692040T3/fi active
- 2018-10-05 CN CN202310780889.9A patent/CN116942663A/zh active Pending
- 2018-10-05 CN CN201880078910.8A patent/CN111433206B/zh active Active
- 2018-10-05 EP EP18795809.5A patent/EP3692040B1/en active Active
- 2018-10-05 LT LTEPPCT/IB2018/057767T patent/LT3692040T/lt unknown
- 2018-10-05 AU AU2018344926A patent/AU2018344926A1/en not_active Abandoned
- 2018-10-05 SG SG10202111648YA patent/SG10202111648YA/en unknown
- 2018-10-05 SI SI201830862T patent/SI3692040T1/sl unknown
- 2018-10-05 MX MX2020003382A patent/MX2020003382A/es unknown
-
2020
- 2020-03-25 PH PH12020550145A patent/PH12020550145A1/en unknown
- 2020-04-02 IL IL273769A patent/IL273769A/en unknown
- 2020-04-03 CO CONC2020/0004202A patent/CO2020004202A2/es unknown
- 2020-04-03 CL CL2020000912A patent/CL2020000912A1/es unknown
-
2021
- 2021-06-04 AU AU2021203650A patent/AU2021203650B9/en active Active
- 2021-10-25 US US17/509,769 patent/US20220144834A1/en active Pending
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